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The map label for this gene is bla [H]

Identifier: 118578628

GI number: 118578628

Start: 184864

End: 185730

Strand: Direct

Name: bla [H]

Synonym: Ppro_0184

Alternate gene names: 118578628

Gene position: 184864-185730 (Clockwise)

Preceding gene: 118578627

Following gene: 118578629

Centisome position: 4.61

GC content: 56.06

Gene sequence:

>867_bases
ATGGTCGCGACAATCCGTATCCATATCGGGGCGATGTTGTCAATTCTCGTGATGTGGGCCGGCATGGCCCATGCCGGCGA
TATTGACCAAAAGTCACTGACGAAGCTCTTCACCGGTTATGACGGCTGCTTCATGCTCTACAACCAGAGCACGGAAAAGC
TGGTCCTGGAATACAACCCTGACAACCGCTGCAGTCAGCGTATCCCCGTCAATTCGACCTTCAAGATCCCGCTGGCCGTC
ATGGCTTTCGATCAGGGGCTCATCACCGAAAGCACCGTGTTCACCTGGGACGGCAAGGTTAATCAGGACTTTCCGGACTG
GAACAGGGATCAGACCCCGGCGTCATGGCAGAAATATTCCGTCGTGTGGGTATCGCAGCAGCTCACACCGAGAATCGGCA
GGGAGATGATCAGCCGATACCTTGCTGTGTTTTCGTACGGCAACCAGGACTTTTCCGGAGACCCCGGCAAGAACAACGGC
CTGACCCACGCCTGGCTCAGCAGCAGTCTGAAAATTTCCGCTGTGGAACAGCTTGAGTTCCTGAAGAAGATAATCAGCTA
CCAGCTGCCCGTGAAGCCAGCGGCAGTCGATTTCACCAAACGGCACCTCTATCAGGGCAAGCTGGAAAATGGTGCTGGCT
ACTACGCCAAGACCGGCAGCGGCTGGCAGGGACGCAGTGACGCCGGCAACAACGCGGGCAAGTTACGCGACGGCTGGTAT
GTCGGGTTCATCGACCATGGCCCGGAGCAGTATGTCTTCGTGTCGAATATCAGCGACAAACGGCCTGATCCGGCATCAAA
GGCTTTCGGCGGGCAGATCTCGAAAGGTATCGCCCTGAGCATCCTAAATGGTTATTTCGGGAAGTGA

Upstream 100 bases:

>100_bases
ACCATCAAGGCCGGCGACCTCGTGGCGTTCCCCGCCGGGATGTCCTGCCGCTGGAATGTCCTCAAGGCCGTTCACAAGCA
CTACCAGTTCGACTGACGTC

Downstream 100 bases:

>100_bases
CCAAGCGGCATCGCATGGCAGTGCCGGTCCCGGACCGGGCTCCCTCCTCGCCGTAGACCTTGGGCTGAAAACCGGCCTTG
CCCTGTTCACTCGGGACGGC

Product: beta-lactamase

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MVATIRIHIGAMLSILVMWAGMAHAGDIDQKSLTKLFTGYDGCFMLYNQSTEKLVLEYNPDNRCSQRIPVNSTFKIPLAV
MAFDQGLITESTVFTWDGKVNQDFPDWNRDQTPASWQKYSVVWVSQQLTPRIGREMISRYLAVFSYGNQDFSGDPGKNNG
LTHAWLSSSLKISAVEQLEFLKKIISYQLPVKPAAVDFTKRHLYQGKLENGAGYYAKTGSGWQGRSDAGNNAGKLRDGWY
VGFIDHGPEQYVFVSNISDKRPDPASKAFGGQISKGIALSILNGYFGK

Sequences:

>Translated_288_residues
MVATIRIHIGAMLSILVMWAGMAHAGDIDQKSLTKLFTGYDGCFMLYNQSTEKLVLEYNPDNRCSQRIPVNSTFKIPLAV
MAFDQGLITESTVFTWDGKVNQDFPDWNRDQTPASWQKYSVVWVSQQLTPRIGREMISRYLAVFSYGNQDFSGDPGKNNG
LTHAWLSSSLKISAVEQLEFLKKIISYQLPVKPAAVDFTKRHLYQGKLENGAGYYAKTGSGWQGRSDAGNNAGKLRDGWY
VGFIDHGPEQYVFVSNISDKRPDPASKAFGGQISKGIALSILNGYFGK
>Mature_288_residues
MVATIRIHIGAMLSILVMWAGMAHAGDIDQKSLTKLFTGYDGCFMLYNQSTEKLVLEYNPDNRCSQRIPVNSTFKIPLAV
MAFDQGLITESTVFTWDGKVNQDFPDWNRDQTPASWQKYSVVWVSQQLTPRIGREMISRYLAVFSYGNQDFSGDPGKNNG
LTHAWLSSSLKISAVEQLEFLKKIISYQLPVKPAAVDFTKRHLYQGKLENGAGYYAKTGSGWQGRSDAGNNAGKLRDGWY
VGFIDHGPEQYVFVSNISDKRPDPASKAFGGQISKGIALSILNGYFGK

Specific function: This is an oxacillin-hydrolyzing beta-lactamase [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32091; Mature: 32091

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATIRIHIGAMLSILVMWAGMAHAGDIDQKSLTKLFTGYDGCFMLYNQSTEKLVLEYNP
CEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
DNRCSQRIPVNSTFKIPLAVMAFDQGLITESTVFTWDGKVNQDFPDWNRDQTPASWQKYS
CCCHHCCCCCCCCEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VVWVSQQLTPRIGREMISRYLAVFSYGNQDFSGDPGKNNGLTHAWLSSSLKISAVEQLEF
EEEECCHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHH
LKKIISYQLPVKPAAVDFTKRHLYQGKLENGAGYYAKTGSGWQGRSDAGNNAGKLRDGWY
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
VGFIDHGPEQYVFVSNISDKRPDPASKAFGGQISKGIALSILNGYFGK
EEEEECCCCCEEEEECCCCCCCCCHHHHCCCHHCCCCCEEEHHHCCCC
>Mature Secondary Structure
MVATIRIHIGAMLSILVMWAGMAHAGDIDQKSLTKLFTGYDGCFMLYNQSTEKLVLEYNP
CEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
DNRCSQRIPVNSTFKIPLAVMAFDQGLITESTVFTWDGKVNQDFPDWNRDQTPASWQKYS
CCCHHCCCCCCCCEECCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
VVWVSQQLTPRIGREMISRYLAVFSYGNQDFSGDPGKNNGLTHAWLSSSLKISAVEQLEF
EEEECCHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHH
LKKIISYQLPVKPAAVDFTKRHLYQGKLENGAGYYAKTGSGWQGRSDAGNNAGKLRDGWY
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
VGFIDHGPEQYVFVSNISDKRPDPASKAFGGQISKGIALSILNGYFGK
EEEEECCCCCEEEEECCCCCCCCCHHHHCCCHHCCCCCEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2823258 [H]