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The map label for this gene is levR [H]

Identifier: 118480239

GI number: 118480239

Start: 4941137

End: 4943812

Strand: Direct

Name: levR [H]

Synonym: BALH_4697

Alternate gene names: 118480239

Gene position: 4941137-4943812 (Clockwise)

Preceding gene: 118480238

Following gene: 118480241

Centisome position: 93.99

GC content: 35.76

Gene sequence:

>2676_bases
ATGAAACGAATAGATCTCATTTTTAACGCAATACAAGAAGGCAAGTATACAGAAGGTGTAACCGCATCAGAACTCGCTAC
CCTGTTGCAACTAGATCGCGCCAATGTAAGTAGCGACTTAAACAAACTTGTAAAAGATAAACGTTTATTAAAAACAAATA
CGCGTCCTGTTCGTTTTTATATAGAAACGAACACTTTGTTGGAAACGCATTCAAAAGAGGTAACTTCATTAGATACATTT
GCAATTGAAAATACGAGCCTTAAAATCGCAATTGAAAAAGCGAAAGCTTCTATTCTCTATCCTCCAAACGGTATGCATAC
TTTACTGCTCGGAGAAACGGGCGTCGGAAAATCTATGTTTGCTTCTTTAATGCACGAATATGCAATTGAAGTGGAACAGC
TTCCTAAAAACGCACCATTTATCGTCTTTAACTGTGCTGATTATGCAAATAATCCACAGCTACTACTCGGGCAGTTATTT
GGGATTAAAAAAGGAGCTTATACAGGGGCAAGTGATCAAAAAGGGTTAATTGAAAAAGCACATGAAGGAATTCTTTTCTT
AGATGAAGTACATCGCCTTCCTCCAGAGGGACAAGAAATGCTTTTCACCTTTATTGACCGCGGAGTATATCGCCGCCTTG
GAGAAACAGAAAACGAGCGTAAAGCACAAGTATTAATCATTACTGCAACAACAGAAGAACCAAATTCATTTTTATTAAAA
ACATTTACAAGACGTATACCAATGACTGTCACATTGCCACCACTTCGTGAGCGTACACATAAAGAACGTTTTGCTTTACT
GCAACTATTTTTCACAAATGAAGCAATTCGCTTGCGAAAAGAAATTCACGTTAGTCCGAATGCAATGCGTGCTTTCGTCT
TTTACAATTGTCCTAATAACATCGGTCAATTAAAAACGGATGTACAAATTGCCTGTGCGAAAGCCTATTCTGACTTCGTG
ACAAAGAAACGTGATTCTGTCTATGTTTCAAGTACAGACTTACCTTGGTATATGAAAGAAGGACTATTCATTGAAAGAAA
GAGCCGTCACCTATACCAAATACCAAATGAAACATTTATATTTACAAGTGATGAAGGTTGGAGTAATCATAAAATAGAAA
ATGAAAAACAATCTTCTATTTACGATTATATTGATTATAAATATGAAGAACTTCAAGCGCGTGGTATTGAAGAAGAAGAA
TTAGAGTTGCTAATAGAAAATGATATTCAAAGCTTTTTCGTACAATATTTTAACCAAATGTCAAAAAAGACAAGTCATGA
AAATGTTTTTAAAATTGTGGATCGTAATATCGTTTCCGTTTGTGAAAGAATTGCAGAACTGGCTGAAAAACATTTATCTA
AGACGTTTGATGAAAAAGTATTTCTCGCTTTAAGTTTACATGTACAGACAACTCTACAACGTTTACAAGCTGGAAAACAA
ATTCATCACCCACAATTAAATCAAATTCGTACGAAATATAAAGAAGCTTTTTCCGTAGCAATGCAATGCATTCAACTACT
GGAGGATGAATTACAAATAACAATGCCTATCGATGAAGCAGGCTTTTTAACAATGTTCTTCGTTGTTGATCCAATTCCTG
CCTCACAAACAGAAGTAAAAGTATTAATATTAGCGCACGGCAACGGCATAGCAACAGAAATGGCAAACGTCGCAAACGAA
CTGCTCGGCATTGATGAAGTAACCGGGATCGATATGCCGTTACATGAATCGCCGAAAGATTTCTTAGAGCGTGTGAAAGT
GTATATGAAAACACTCCAAAATGTAAACGGGCTTCTCTTACTCGTTGATATGGGATCACTCGCTTACATTGGTGATATAT
TAGAAACTGAGTTCAAAATCCCGGTACGTGTTCTTTCCATGACAAGCACTCCACATGCACTAGAAGCTGCTCGAAAAGCT
CAGCTTGGCTACTCGTTAGATGCATTATATGAAACAGTGAAGAACTTAACACCGTTTTACTTAAACGTACAAGAAGAAAA
GAAAAAGCCGCTATCACCAATGAAATCTGTTATTTTGACAGCTTGTTTAACTGGGGAAGGTAGTGCTTTAGCTATTCAAA
AAATGTTGGAGAACTATTTGCGATTTGACAAAGACTTAATTGAAATTATTCCGATTAGTATCGTCCATGAAAAAGATTTA
ACAAAAATGATTGAGAACATAAAAAAAGAGCGAAATATCATTTGTATTGTTACGAATTTTGATGTACAAGTGCCATGCTT
AACTTATCACTTCCAAGACATTGTAAACTACACAGCAATTCAGCCAATTCAAGAATTAATTACGTATGAAGAAACATATG
CAAAAATGGCTGATATCCTTGAACAACAAATGCAGCGTAACGACGGAGCATTACTTATTAAAACGATCCGTTACGCATTA
AATACAATTCAAGAATTAATTTCCTTACAGCTAACTCCTGACAGTTTAATGGGTGTTATTCTGCATATGAGCTGTATGGT
TGACCGTCTTCAAAAAGGAGAAAGCCTCCTCCCTCATCCGGATAAAGAGAAACGAAGACAAGATGAATACTGGATGTATA
TGAAAGTAAAAAAAGCATTGCAGCCAATTGAAAATACATTTGAAATACAAATACCTGATGACGAAGTGTTTTATGTAATG
GACTTCTTCATTAAAAATCAGCCCGTAAAAAATTAG

Upstream 100 bases:

>100_bases
TTTAGTACCTATATACTAAAGCTGTTTTATTTTTCTCTTCCCACCCTTCCCATTTTTGTGTAAAATTTTAAATAGTGATG
AAGTTTCGAGGTGAATAGAA

Downstream 100 bases:

>100_bases
TCACGGCAGTTTTTTAGTATATTGATCTTAACTCAGATTTTATCAGCGATTTTCAGGATATATCAGCGCAACTCGGGTTT
TATCAGCGATTTTCAAAATA

Product: transcriptional antiterminator

Products: NA

Alternate protein names: Putative phosphotransferase EIIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 891; Mature: 891

Protein sequence:

>891_residues
MKRIDLIFNAIQEGKYTEGVTASELATLLQLDRANVSSDLNKLVKDKRLLKTNTRPVRFYIETNTLLETHSKEVTSLDTF
AIENTSLKIAIEKAKASILYPPNGMHTLLLGETGVGKSMFASLMHEYAIEVEQLPKNAPFIVFNCADYANNPQLLLGQLF
GIKKGAYTGASDQKGLIEKAHEGILFLDEVHRLPPEGQEMLFTFIDRGVYRRLGETENERKAQVLIITATTEEPNSFLLK
TFTRRIPMTVTLPPLRERTHKERFALLQLFFTNEAIRLRKEIHVSPNAMRAFVFYNCPNNIGQLKTDVQIACAKAYSDFV
TKKRDSVYVSSTDLPWYMKEGLFIERKSRHLYQIPNETFIFTSDEGWSNHKIENEKQSSIYDYIDYKYEELQARGIEEEE
LELLIENDIQSFFVQYFNQMSKKTSHENVFKIVDRNIVSVCERIAELAEKHLSKTFDEKVFLALSLHVQTTLQRLQAGKQ
IHHPQLNQIRTKYKEAFSVAMQCIQLLEDELQITMPIDEAGFLTMFFVVDPIPASQTEVKVLILAHGNGIATEMANVANE
LLGIDEVTGIDMPLHESPKDFLERVKVYMKTLQNVNGLLLLVDMGSLAYIGDILETEFKIPVRVLSMTSTPHALEAARKA
QLGYSLDALYETVKNLTPFYLNVQEEKKKPLSPMKSVILTACLTGEGSALAIQKMLENYLRFDKDLIEIIPISIVHEKDL
TKMIENIKKERNIICIVTNFDVQVPCLTYHFQDIVNYTAIQPIQELITYEETYAKMADILEQQMQRNDGALLIKTIRYAL
NTIQELISLQLTPDSLMGVILHMSCMVDRLQKGESLLPHPDKEKRRQDEYWMYMKVKKALQPIENTFEIQIPDDEVFYVM
DFFIKNQPVKN

Sequences:

>Translated_891_residues
MKRIDLIFNAIQEGKYTEGVTASELATLLQLDRANVSSDLNKLVKDKRLLKTNTRPVRFYIETNTLLETHSKEVTSLDTF
AIENTSLKIAIEKAKASILYPPNGMHTLLLGETGVGKSMFASLMHEYAIEVEQLPKNAPFIVFNCADYANNPQLLLGQLF
GIKKGAYTGASDQKGLIEKAHEGILFLDEVHRLPPEGQEMLFTFIDRGVYRRLGETENERKAQVLIITATTEEPNSFLLK
TFTRRIPMTVTLPPLRERTHKERFALLQLFFTNEAIRLRKEIHVSPNAMRAFVFYNCPNNIGQLKTDVQIACAKAYSDFV
TKKRDSVYVSSTDLPWYMKEGLFIERKSRHLYQIPNETFIFTSDEGWSNHKIENEKQSSIYDYIDYKYEELQARGIEEEE
LELLIENDIQSFFVQYFNQMSKKTSHENVFKIVDRNIVSVCERIAELAEKHLSKTFDEKVFLALSLHVQTTLQRLQAGKQ
IHHPQLNQIRTKYKEAFSVAMQCIQLLEDELQITMPIDEAGFLTMFFVVDPIPASQTEVKVLILAHGNGIATEMANVANE
LLGIDEVTGIDMPLHESPKDFLERVKVYMKTLQNVNGLLLLVDMGSLAYIGDILETEFKIPVRVLSMTSTPHALEAARKA
QLGYSLDALYETVKNLTPFYLNVQEEKKKPLSPMKSVILTACLTGEGSALAIQKMLENYLRFDKDLIEIIPISIVHEKDL
TKMIENIKKERNIICIVTNFDVQVPCLTYHFQDIVNYTAIQPIQELITYEETYAKMADILEQQMQRNDGALLIKTIRYAL
NTIQELISLQLTPDSLMGVILHMSCMVDRLQKGESLLPHPDKEKRRQDEYWMYMKVKKALQPIENTFEIQIPDDEVFYVM
DFFIKNQPVKN
>Mature_891_residues
MKRIDLIFNAIQEGKYTEGVTASELATLLQLDRANVSSDLNKLVKDKRLLKTNTRPVRFYIETNTLLETHSKEVTSLDTF
AIENTSLKIAIEKAKASILYPPNGMHTLLLGETGVGKSMFASLMHEYAIEVEQLPKNAPFIVFNCADYANNPQLLLGQLF
GIKKGAYTGASDQKGLIEKAHEGILFLDEVHRLPPEGQEMLFTFIDRGVYRRLGETENERKAQVLIITATTEEPNSFLLK
TFTRRIPMTVTLPPLRERTHKERFALLQLFFTNEAIRLRKEIHVSPNAMRAFVFYNCPNNIGQLKTDVQIACAKAYSDFV
TKKRDSVYVSSTDLPWYMKEGLFIERKSRHLYQIPNETFIFTSDEGWSNHKIENEKQSSIYDYIDYKYEELQARGIEEEE
LELLIENDIQSFFVQYFNQMSKKTSHENVFKIVDRNIVSVCERIAELAEKHLSKTFDEKVFLALSLHVQTTLQRLQAGKQ
IHHPQLNQIRTKYKEAFSVAMQCIQLLEDELQITMPIDEAGFLTMFFVVDPIPASQTEVKVLILAHGNGIATEMANVANE
LLGIDEVTGIDMPLHESPKDFLERVKVYMKTLQNVNGLLLLVDMGSLAYIGDILETEFKIPVRVLSMTSTPHALEAARKA
QLGYSLDALYETVKNLTPFYLNVQEEKKKPLSPMKSVILTACLTGEGSALAIQKMLENYLRFDKDLIEIIPISIVHEKDL
TKMIENIKKERNIICIVTNFDVQVPCLTYHFQDIVNYTAIQPIQELITYEETYAKMADILEQQMQRNDGALLIKTIRYAL
NTIQELISLQLTPDSLMGVILHMSCMVDRLQKGESLLPHPDKEKRRQDEYWMYMKVKKALQPIENTFEIQIPDDEVFYVM
DFFIKNQPVKN

Specific function: Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system, and sacA for levanase [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=8e-19,
Organism=Escherichia coli, GI1789233, Length=213, Percent_Identity=31.924882629108, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=214, Percent_Identity=31.7757009345794, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87082117, Length=213, Percent_Identity=32.8638497652582, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081872, Length=254, Percent_Identity=31.496062992126, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786524, Length=229, Percent_Identity=31.0043668122271, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788905, Length=228, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082152, Length=258, Percent_Identity=30.6201550387597, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=215, Percent_Identity=32.093023255814, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787583, Length=249, Percent_Identity=26.9076305220884, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1789087, Length=213, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011608
- InterPro:   IPR004701
- InterPro:   IPR002078
- InterPro:   IPR001550 [H]

Pfam domain/function: PF03610 EIIA-man; PF00874 PRD; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 102303; Mature: 102303

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00690 DEAH_ATP_HELICASE ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4 ; PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIDLIFNAIQEGKYTEGVTASELATLLQLDRANVSSDLNKLVKDKRLLKTNTRPVRFY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEE
IETNTLLETHSKEVTSLDTFAIENTSLKIAIEKAKASILYPPNGMHTLLLGETGVGKSMF
EECCCHHHHCCCHHHHHHHEEEECCEEEEEEEECCCEEEECCCCCEEEEEECCCCCHHHH
ASLMHEYAIEVEQLPKNAPFIVFNCADYANNPQLLLGQLFGIKKGAYTGASDQKGLIEKA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
HEGILFLDEVHRLPPEGQEMLFTFIDRGVYRRLGETENERKAQVLIITATTEEPNSFLLK
HCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHH
TFTRRIPMTVTLPPLRERTHKERFALLQLFFTNEAIRLRKEIHVSPNAMRAFVFYNCPNN
HHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEEECCCC
IGQLKTDVQIACAKAYSDFVTKKRDSVYVSSTDLPWYMKEGLFIERKSRHLYQIPNETFI
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCEEEEECCCCEEECCCCEEE
FTSDEGWSNHKIENEKQSSIYDYIDYKYEELQARGIEEEELELLIENDIQSFFVQYFNQM
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKKTSHENVFKIVDRNIVSVCERIAELAEKHLSKTFDEKVFLALSLHVQTTLQRLQAGKQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCC
IHHPQLNQIRTKYKEAFSVAMQCIQLLEDELQITMPIDEAGFLTMFFVVDPIPASQTEVK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCEE
VLILAHGNGIATEMANVANELLGIDEVTGIDMPLHESPKDFLERVKVYMKTLQNVNGLLL
EEEEECCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
LVDMGSLAYIGDILETEFKIPVRVLSMTSTPHALEAARKAQLGYSLDALYETVKNLTPFY
EEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEE
LNVQEEKKKPLSPMKSVILTACLTGEGSALAIQKMLENYLRFDKDLIEIIPISIVHEKDL
EEECHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCHHEECHHHH
TKMIENIKKERNIICIVTNFDVQVPCLTYHFQDIVNYTAIQPIQELITYEETYAKMADIL
HHHHHHHHHCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQMQRNDGALLIKTIRYALNTIQELISLQLTPDSLMGVILHMSCMVDRLQKGESLLPHP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DKEKRRQDEYWMYMKVKKALQPIENTFEIQIPDDEVFYVMDFFIKNQPVKN
CHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRIDLIFNAIQEGKYTEGVTASELATLLQLDRANVSSDLNKLVKDKRLLKTNTRPVRFY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEE
IETNTLLETHSKEVTSLDTFAIENTSLKIAIEKAKASILYPPNGMHTLLLGETGVGKSMF
EECCCHHHHCCCHHHHHHHEEEECCEEEEEEEECCCEEEECCCCCEEEEEECCCCCHHHH
ASLMHEYAIEVEQLPKNAPFIVFNCADYANNPQLLLGQLFGIKKGAYTGASDQKGLIEKA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
HEGILFLDEVHRLPPEGQEMLFTFIDRGVYRRLGETENERKAQVLIITATTEEPNSFLLK
HCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHH
TFTRRIPMTVTLPPLRERTHKERFALLQLFFTNEAIRLRKEIHVSPNAMRAFVFYNCPNN
HHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEEECCCC
IGQLKTDVQIACAKAYSDFVTKKRDSVYVSSTDLPWYMKEGLFIERKSRHLYQIPNETFI
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCEEEEECCCCEEECCCCEEE
FTSDEGWSNHKIENEKQSSIYDYIDYKYEELQARGIEEEELELLIENDIQSFFVQYFNQM
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKKTSHENVFKIVDRNIVSVCERIAELAEKHLSKTFDEKVFLALSLHVQTTLQRLQAGKQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCC
IHHPQLNQIRTKYKEAFSVAMQCIQLLEDELQITMPIDEAGFLTMFFVVDPIPASQTEVK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCCEE
VLILAHGNGIATEMANVANELLGIDEVTGIDMPLHESPKDFLERVKVYMKTLQNVNGLLL
EEEEECCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
LVDMGSLAYIGDILETEFKIPVRVLSMTSTPHALEAARKAQLGYSLDALYETVKNLTPFY
EEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEE
LNVQEEKKKPLSPMKSVILTACLTGEGSALAIQKMLENYLRFDKDLIEIIPISIVHEKDL
EEECHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCHHEECHHHH
TKMIENIKKERNIICIVTNFDVQVPCLTYHFQDIVNYTAIQPIQELITYEETYAKMADIL
HHHHHHHHHCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQMQRNDGALLIKTIRYALNTIQELISLQLTPDSLMGVILHMSCMVDRLQKGESLLPHP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DKEKRRQDEYWMYMKVKKALQPIENTFEIQIPDDEVFYVMDFFIKNQPVKN
CHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1900939; 9141695; 9384377 [H]