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The map label for this gene is iunH [H]

Identifier: 118480171

GI number: 118480171

Start: 4870578

End: 4871528

Strand: Direct

Name: iunH [H]

Synonym: BALH_4626

Alternate gene names: 118480171

Gene position: 4870578-4871528 (Clockwise)

Preceding gene: 118480160

Following gene: 118480180

Centisome position: 92.65

GC content: 37.96

Gene sequence:

>951_bases
ATGCCCAAAAAAGTTCTTATTTTTTGTGATCCTGGCATTGATGATACGATGGCTCTCCTCTTAGCATTCTTTATCGATGA
AATAGAAATCATCGGCATTGTTGCTGATTACGGCAATGTTCCAAAGAAGATGGCCGTACAAAATGCTCATTTCCTTAAGA
ATGAAACAAGGAATAGAAATATTAAGATATTCGGTGGTTCAGAACGCCCTCTTACTGGTGCCCCGCCTGCTTTTTTTACA
GAAGTACACGGGAAACAAGGGCTTGGGCCAATTATTCCAAATGGGAATGTGACTAACGGAGAAATGGAGAATTTCTTTGA
AGTCATTCCTCTTATTGAACACTATAAAGATGAATTAATTATTGTAAGTTTAGGAAGACTTACCTCTCTAGCAATTTTGT
TTATTATGTGCAAACAGTTAATGAAACAAATTAAATCTTACTACGTAATGGGCGGTGCCTTTTTACACCCTGGTAATGTT
ACCCCTATTTCCGAAGCAAATTTTTATGGCGATCCTACTGCCGCTAACATTGTTCTTCAATCTGCAGCGAACATGTACAT
ATACCCGTTAAACGTTACCCAATACTCCGTCATTACACCAGAAATGGCCGAGTACATTGAAGCAAAAGGAAAAGCCCCAC
TCGTCAAACCGTTATTCGATCATTATTACTATGGATATTATAAAAATGCCCTGCCAGATTTAAAAGGTAGCCCCTTCCAT
GACACAATGCCGATACTGGCTTTACTTGATAACTCTATGTTTACGTATCACAAATCACCTATCGTTGTCATGACAGAATC
TTATGCACAAGGAGCAAGCATTGGAGAATTTCGTTCCTTAGGAAACTCTAAACCATTTATGGATTGGCCGAGTCATCAAA
TCGCAATTGATTTTGATTATAACCGTTTCTTTAAGCATTTCATGTCACTTATGACTGATGAAGAATTTTAG

Upstream 100 bases:

>100_bases
AGAAGTTTTTATTTTCTGAATTTTAAAGGTTGTTATTTCAATAAAATAATCTTTTTATTCTTAAGCTTACATATATATAA
AGAAGATAGGTGGTGAACAT

Downstream 100 bases:

>100_bases
CATAAAAAAACAGACCGTGATTTCTCACGGTCTGTCGTTATTTTCTACAATTATCGTTTGATGTTATAGAAAGATTTGAT
ACCATCGTAAACAGCGATTT

Product: inosine-uridine preferring nucleoside hydrolase

Products: D-ribose; purine

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPKKVLIFCDPGIDDTMALLLAFFIDEIEIIGIVADYGNVPKKMAVQNAHFLKNETRNRNIKIFGGSERPLTGAPPAFFT
EVHGKQGLGPIIPNGNVTNGEMENFFEVIPLIEHYKDELIIVSLGRLTSLAILFIMCKQLMKQIKSYYVMGGAFLHPGNV
TPISEANFYGDPTAANIVLQSAANMYIYPLNVTQYSVITPEMAEYIEAKGKAPLVKPLFDHYYYGYYKNALPDLKGSPFH
DTMPILALLDNSMFTYHKSPIVVMTESYAQGASIGEFRSLGNSKPFMDWPSHQIAIDFDYNRFFKHFMSLMTDEEF

Sequences:

>Translated_316_residues
MPKKVLIFCDPGIDDTMALLLAFFIDEIEIIGIVADYGNVPKKMAVQNAHFLKNETRNRNIKIFGGSERPLTGAPPAFFT
EVHGKQGLGPIIPNGNVTNGEMENFFEVIPLIEHYKDELIIVSLGRLTSLAILFIMCKQLMKQIKSYYVMGGAFLHPGNV
TPISEANFYGDPTAANIVLQSAANMYIYPLNVTQYSVITPEMAEYIEAKGKAPLVKPLFDHYYYGYYKNALPDLKGSPFH
DTMPILALLDNSMFTYHKSPIVVMTESYAQGASIGEFRSLGNSKPFMDWPSHQIAIDFDYNRFFKHFMSLMTDEEF
>Mature_315_residues
PKKVLIFCDPGIDDTMALLLAFFIDEIEIIGIVADYGNVPKKMAVQNAHFLKNETRNRNIKIFGGSERPLTGAPPAFFTE
VHGKQGLGPIIPNGNVTNGEMENFFEVIPLIEHYKDELIIVSLGRLTSLAILFIMCKQLMKQIKSYYVMGGAFLHPGNVT
PISEANFYGDPTAANIVLQSAANMYIYPLNVTQYSVITPEMAEYIEAKGKAPLVKPLFDHYYYGYYKNALPDLKGSPFHD
TMPILALLDNSMFTYHKSPIVVMTESYAQGASIGEFRSLGNSKPFMDWPSHQIAIDFDYNRFFKHFMSLMTDEEF

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=307, Percent_Identity=29.3159609120521, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788486, Length=251, Percent_Identity=25.0996015936255, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786213, Length=305, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32565474, Length=188, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320608, Length=258, Percent_Identity=28.2945736434109, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 35588; Mature: 35456

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKVLIFCDPGIDDTMALLLAFFIDEIEIIGIVADYGNVPKKMAVQNAHFLKNETRNRN
CCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCE
IKIFGGSERPLTGAPPAFFTEVHGKQGLGPIIPNGNVTNGEMENFFEVIPLIEHYKDELI
EEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
IVSLGRLTSLAILFIMCKQLMKQIKSYYVMGGAFLHPGNVTPISEANFYGDPTAANIVLQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCCCCCCCCCHHHHHHHC
SAANMYIYPLNVTQYSVITPEMAEYIEAKGKAPLVKPLFDHYYYGYYKNALPDLKGSPFH
CCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DTMPILALLDNSMFTYHKSPIVVMTESYAQGASIGEFRSLGNSKPFMDWPSHQIAIDFDY
HHHHHHHHHCCCEEEEECCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECH
NRFFKHFMSLMTDEEF
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKKVLIFCDPGIDDTMALLLAFFIDEIEIIGIVADYGNVPKKMAVQNAHFLKNETRNRN
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCE
IKIFGGSERPLTGAPPAFFTEVHGKQGLGPIIPNGNVTNGEMENFFEVIPLIEHYKDELI
EEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
IVSLGRLTSLAILFIMCKQLMKQIKSYYVMGGAFLHPGNVTPISEANFYGDPTAANIVLQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCCCCCCCCCHHHHHHHC
SAANMYIYPLNVTQYSVITPEMAEYIEAKGKAPLVKPLFDHYYYGYYKNALPDLKGSPFH
CCCCEEEEEECCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DTMPILALLDNSMFTYHKSPIVVMTESYAQGASIGEFRSLGNSKPFMDWPSHQIAIDFDY
HHHHHHHHHCCCEEEEECCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECH
NRFFKHFMSLMTDEEF
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA