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The map label for this gene is lytH [H]

Identifier: 118480057

GI number: 118480057

Start: 4743853

End: 4744932

Strand: Direct

Name: lytH [H]

Synonym: BALH_4505

Alternate gene names: 118480057

Gene position: 4743853-4744932 (Clockwise)

Preceding gene: 118480055

Following gene: 118480061

Centisome position: 90.24

GC content: 40.46

Gene sequence:

>1080_bases
ATGAAGATTCTAAGATTTTTTCCAATCGTTCCCTATAATGAAATACTCCGTATATCCCACACTAAAAAGAGTGATGTTGT
GAAAGGAGTCTATTTCATGCTTCGAAAAATTTCTCTTTTGCTTTCGATTTGCTTTCTTCTCCACCAAAACATCGCTTACG
GTGAAGATAATCAGCAAAGCATATACGAAAAGCGCATGGCACTATATAAAGAAACCGAGCAATCTTCAGGCATTCCGTGG
TATTACTTAGCTGCAATGGATCAATATGAAAGAAATATACGGAGCGTAAGAAAAGATATTCCGAAAAAACCAGATGCCAT
CATTTCCCTTTATTTCAAACCAGAAATATGGGCTGGACCTGTTAATGGTAATGATACTCTCCCCCATACAATTGCTCTAT
TTGGCGGGTTAGGTTTAGATGGTGACAAAGATGGATTTGCAAATGCAAATAACGACCGTGACCTTCTGCATACAGCAGCA
ACAATTTTAAAGAAACAAGGAACGTCAGAAGAACGTATCAAAATCATGCTCTGGGAATATTATAGACGTGCAAAAACAGT
TGATTTAATTACCGAATACGCCCAAATTTATAAACATTATGGACGTATTAATTTAGAAGGAAATGCTTTTCCCCTTCCTA
TTCGCAGTGACCATAGCTACCGTAGTACTTTCGGCGCTGGAAGAAGTTTTGGTGGAAGAAGGGTTCATGAAGGAACCGAT
ATATTCGCAGGCTATGGCGTACCAGTAAGATCCACTTGCTATGGCATTATTGAAACAAAGGGCTGGAATCGCCTTGGCGG
ATGGCGCATCGGTATTCGCGACCTTCATAATAATTATCATTATTACGCTCACTTAGGCGGGTTCTCAAAAGAAATACAGC
TTGGACAAATTGTCGAGCCCGGAAAAGTAATCGGATTTGTTGGTAGCACCGGTTACGGTCCTCCCGGCACAGCTGGAAAA
TTCCCGCCTCACTTACATTTCGGCATGTATAAAGACAACGGTTATACAGAATGGGCTTTCGATCCATACATGCATTTAAG
TCTTTGGGAGCGAAAAGAACGCGCAAATACAAAACGATAA

Upstream 100 bases:

>100_bases
TTGTCATGGTTATCAACTCCGCACAATATGAAATAGTTTACCGTGTTCGCTTCTTTCAATGTAACATATCTATTCTAACG
TATGAAAGCGATTTGCTCAA

Downstream 100 bases:

>100_bases
CCGTAGCACATTGCTACGGTTATTTTTCAACTAACTATCCGTTTTCTTTTTATTAGGTACAACAACACTTCCGCTTCCAT
AATAAGTAGGCACTTCTCCT

Product: M24/M37 family peptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKILRFFPIVPYNEILRISHTKKSDVVKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPW
YYLAAMDQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAA
TILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTD
IFAGYGVPVRSTCYGIIETKGWNRLGGWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGK
FPPHLHFGMYKDNGYTEWAFDPYMHLSLWERKERANTKR

Sequences:

>Translated_359_residues
MKILRFFPIVPYNEILRISHTKKSDVVKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPW
YYLAAMDQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAA
TILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTD
IFAGYGVPVRSTCYGIIETKGWNRLGGWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGK
FPPHLHFGMYKDNGYTEWAFDPYMHLSLWERKERANTKR
>Mature_359_residues
MKILRFFPIVPYNEILRISHTKKSDVVKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPW
YYLAAMDQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAA
TILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTD
IFAGYGVPVRSTCYGIIETKGWNRLGGWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGK
FPPHLHFGMYKDNGYTEWAFDPYMHLSLWERKERANTKR

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 41149; Mature: 41149

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILRFFPIVPYNEILRISHTKKSDVVKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQS
CCCEEEECCCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
IYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGP
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC
VNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEY
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YRRAKTVDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTD
HHHHHHHHHHHHHHHHHHHHCEEEECCCEEECCCCCCCCHHHHHCCCCCCCCCEECCCCC
IFAGYGVPVRSTCYGIIETKGWNRLGGWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEP
EEEECCCCHHHHEEEEEECCCCCCCCCEEEEHHHHCCCEEEEEEECCCCCCCCCCCCCCC
GKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHLSLWERKERANTKR
CCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKILRFFPIVPYNEILRISHTKKSDVVKGVYFMLRKISLLLSICFLLHQNIAYGEDNQQS
CCCEEEECCCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
IYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDAIISLYFKPEIWAGP
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC
VNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEY
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YRRAKTVDLITEYAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTD
HHHHHHHHHHHHHHHHHHHHCEEEECCCEEECCCCCCCCHHHHHCCCCCCCCCEECCCCC
IFAGYGVPVRSTCYGIIETKGWNRLGGWRIGIRDLHNNYHYYAHLGGFSKEIQLGQIVEP
EEEECCCCHHHHEEEEEECCCCCCCCCEEEEHHHHCCCEEEEEEECCCCCCCCCCCCCCC
GKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHLSLWERKERANTKR
CCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]