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The map label for this gene is menC [H]

Identifier: 118479971

GI number: 118479971

Start: 4638640

End: 4639746

Strand: Reverse

Name: menC [H]

Synonym: BALH_4417

Alternate gene names: 118479971

Gene position: 4639746-4638640 (Counterclockwise)

Preceding gene: 118479972

Following gene: 118479970

Centisome position: 88.26

GC content: 43.0

Gene sequence:

>1107_bases
GTGGAAATAAAAAAAGCGACACTTCATATAACGGAAATGCCACTCGTCATCCCGTTTGCTGCAAGCTACGGAACTTACGA
AAAGCGTGAGAGCATCGTTATTGAATTAGAAGATACGGATGGACATATTGGATTTGGTGAAGTCGTTGCCTTCTCTGAAC
CGTGGTATACGGAAGAAACAGTGAAGACAGCGCTGCATGTACTTCAGGATTTTTTATTACCTGATTTATTGAAAGCTGAA
ATTTCCCACCCGAATGAAGTACCTGGTTTGTTCCAGCATATAAAAAGAAACCGAATGGCAAAGGCTGGAATTGAAGGAGC
TGTTTGGGATTTATATGCGAAGTGTCAAAAGAAATCGTTAGCGACATTGCTTGGCGGAACGAAGTCTGAAATTGAAGTCG
GTGTTGTGGTCGGGATCAATACGATTCCGGTTATGTTAAAACAAATTGAGAAGTATGCGGAAGAAGGATACGAGCGTTTT
AAGGTGAAAATAAAACCGGGGCATGATTATGAGTTATTGAAAGAAATTCGTAAAGAGTTCCCGCACATCCCATTAATGGC
TGATGCAAATTCAGCGTACACGTTAGCGGATATGGGGAAATTGAAACGATTAGATGAATTTCAATTGATGATGATTGAAC
AACCACTAGCGGATTACGACTTTCTTGATCATGCACAGTTGCAAAAGAAAATCGAAACGCCAATTTGCTTAGACGAAAGC
ATCCATAGTTTAGAAGATGCGCGCGTTGCGATTACGCTTGGCAGTTGCCGCATCGTTAATATTAAACCAGGGCGAGTGGG
CGGATTAACAGAATCGATTCAAATTCATAACTATTGTATGGAGCGTAACATCCCTGTTTGGTGCGGCGGTATGGTAGAGA
TGGGGATTTCAAGGGCGCAAAATGTTGCGCTTGCTTCACTGCCGAACTTTACGATTCCTGGCGATATATCCGCTTCTAGT
AGACATTGGGAGAAGGATATTATTTCGCCAGAAGTGACGCTTGAGGGCGGGAAAGTGATGGTGCCGCAAAGTGTTGATAC
TGAGTATGAAGTAGACCACGGAAGGTTGGCTGAAATTACGAAGCAGCGAATTGTTTTGGAGCGGTAG

Upstream 100 bases:

>100_bases
TAAAGTGCCGAAAAAAGCGTGCTTCTTAGAAGAATTACCACGAAATGCTTCGAAAAAATTGTTAAGACGAGAGTTAAGAC
AATTAGTGGAGGAGATGTAA

Downstream 100 bases:

>100_bases
GTTGAGTCTTTCAAATAGCGGGCGAATTTCGTCGTTAATTGTCGGTAAGTCGATATATTTCAATAATCGCTGATATAATT
CGAGTTACGGTCGATATATT

Product: o-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MEIKKATLHITEMPLVIPFAASYGTYEKRESIVIELEDTDGHIGFGEVVAFSEPWYTEETVKTALHVLQDFLLPDLLKAE
ISHPNEVPGLFQHIKRNRMAKAGIEGAVWDLYAKCQKKSLATLLGGTKSEIEVGVVVGINTIPVMLKQIEKYAEEGYERF
KVKIKPGHDYELLKEIRKEFPHIPLMADANSAYTLADMGKLKRLDEFQLMMIEQPLADYDFLDHAQLQKKIETPICLDES
IHSLEDARVAITLGSCRIVNIKPGRVGGLTESIQIHNYCMERNIPVWCGGMVEMGISRAQNVALASLPNFTIPGDISASS
RHWEKDIISPEVTLEGGKVMVPQSVDTEYEVDHGRLAEITKQRIVLER

Sequences:

>Translated_368_residues
MEIKKATLHITEMPLVIPFAASYGTYEKRESIVIELEDTDGHIGFGEVVAFSEPWYTEETVKTALHVLQDFLLPDLLKAE
ISHPNEVPGLFQHIKRNRMAKAGIEGAVWDLYAKCQKKSLATLLGGTKSEIEVGVVVGINTIPVMLKQIEKYAEEGYERF
KVKIKPGHDYELLKEIRKEFPHIPLMADANSAYTLADMGKLKRLDEFQLMMIEQPLADYDFLDHAQLQKKIETPICLDES
IHSLEDARVAITLGSCRIVNIKPGRVGGLTESIQIHNYCMERNIPVWCGGMVEMGISRAQNVALASLPNFTIPGDISASS
RHWEKDIISPEVTLEGGKVMVPQSVDTEYEVDHGRLAEITKQRIVLER
>Mature_368_residues
MEIKKATLHITEMPLVIPFAASYGTYEKRESIVIELEDTDGHIGFGEVVAFSEPWYTEETVKTALHVLQDFLLPDLLKAE
ISHPNEVPGLFQHIKRNRMAKAGIEGAVWDLYAKCQKKSLATLLGGTKSEIEVGVVVGINTIPVMLKQIEKYAEEGYERF
KVKIKPGHDYELLKEIRKEFPHIPLMADANSAYTLADMGKLKRLDEFQLMMIEQPLADYDFLDHAQLQKKIETPICLDES
IHSLEDARVAITLGSCRIVNIKPGRVGGLTESIQIHNYCMERNIPVWCGGMVEMGISRAQNVALASLPNFTIPGDISASS
RHWEKDIISPEVTLEGGKVMVPQSVDTEYEVDHGRLAEITKQRIVLER

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=302, Percent_Identity=28.476821192053, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41352; Mature: 41352

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKKATLHITEMPLVIPFAASYGTYEKRESIVIELEDTDGHIGFGEVVAFSEPWYTEET
CCCCEEEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCHHH
VKTALHVLQDFLLPDLLKAEISHPNEVPGLFQHIKRNRMAKAGIEGAVWDLYAKCQKKSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ATLLGGTKSEIEVGVVVGINTIPVMLKQIEKYAEEGYERFKVKIKPGHDYELLKEIRKEF
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHC
PHIPLMADANSAYTLADMGKLKRLDEFQLMMIEQPLADYDFLDHAQLQKKIETPICLDES
CCCCEEECCCCCEEHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
IHSLEDARVAITLGSCRIVNIKPGRVGGLTESIQIHNYCMERNIPVWCGGMVEMGISRAQ
HHHHCCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHC
NVALASLPNFTIPGDISASSRHWEKDIISPEVTLEGGKVMVPQSVDTEYEVDHGRLAEIT
CEEEECCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCEEECCCCCCCCEECCCCHHHHHH
KQRIVLER
HHHHCCCC
>Mature Secondary Structure
MEIKKATLHITEMPLVIPFAASYGTYEKRESIVIELEDTDGHIGFGEVVAFSEPWYTEET
CCCCEEEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCHHH
VKTALHVLQDFLLPDLLKAEISHPNEVPGLFQHIKRNRMAKAGIEGAVWDLYAKCQKKSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ATLLGGTKSEIEVGVVVGINTIPVMLKQIEKYAEEGYERFKVKIKPGHDYELLKEIRKEF
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHC
PHIPLMADANSAYTLADMGKLKRLDEFQLMMIEQPLADYDFLDHAQLQKKIETPICLDES
CCCCEEECCCCCEEHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
IHSLEDARVAITLGSCRIVNIKPGRVGGLTESIQIHNYCMERNIPVWCGGMVEMGISRAQ
HHHHCCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHC
NVALASLPNFTIPGDISASSRHWEKDIISPEVTLEGGKVMVPQSVDTEYEVDHGRLAEIT
CEEEECCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCEEECCCCCCCCEECCCCHHHHHH
KQRIVLER
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]