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The map label for this gene is kinE [H]

Identifier: 118479904

GI number: 118479904

Start: 4568073

End: 4569329

Strand: Reverse

Name: kinE [H]

Synonym: BALH_4348

Alternate gene names: 118479904

Gene position: 4569329-4568073 (Counterclockwise)

Preceding gene: 118479906

Following gene: 118479903

Centisome position: 86.92

GC content: 32.3

Gene sequence:

>1257_bases
GTGAAAGACAGTTTTCTATCATATAAAGAAGAAGAAAGGAATGCAAAAATCCTTTTGTGGGTGCTATATGTCATTGTTGT
TTCATACCAAATTTTCTATGCAATTGTATTAGAGAATAAATCACTAACAGATAAGGGATATAGCATACTATGGCAAGTTA
TTTGCGGAACTGCAATACTCGGTGTGAATGTATATTTAATAAAAAAAGAGAAAGCGAATTTCGTTAAATATGCATGTGTA
TTTGCATACTTAGGAATAGAAATTGCTAATATACTTTCGTATATGCTTTATAATGAGGCAGCATTTGATGGGGGAAATAT
AATAGAAATTATTCTCATCTTCTTTGTACCTATATTTTTAAATAAAAAATATTTTGTGTTTGTACTGTCAACTATTGTAG
TGAAATATGTGATTTATTTATTTGTATTAAAAGAAGTAAAAGGATTTATGTTCCTCATTATGTATACACTCGTATTAATA
GCGGCATACATCATTTTAAGTCGATTTATACAATACCTTTCAGCGGTAAAGGAAAGTATTAAGGTTGCTAGTGAATCACA
AAAATTAGCAGTAATCGGAAAAATGGCAGCGACAGTGGGACACGAAATTAAAAATCCACTTGCTTCATTAAAAGGGTTTA
CGCAATTACAACGAGAGAAGCATGGGGAGGACCCTATTTACAAACAGATGATTTTTGAAATAGAAAATATGAATAATATG
ATAAGTGAATTGATGGAAGTTGCTACATGTAAACCTTCTATTTATAAGAAACATAATATAGGTGAAATTGTATTACAAGC
AGTAGCAATTCTTCGCGAAAAAATGAATGAATGTAGTGTCCAGCTTATTTCTAATGTTGAAGAAAACATAATAGAAGCTG
AATGTGATGAGCGGAAAATGCGAGGAGTTTTTCTATATGTCATAAAAAATGCTCTGGAGGCAATGGAGCAAGGTGGCACA
TTAGAGTTACGGTTAGAAAATAAAGGACAAGATTATGTAATGTTAAGTGTAATTGATAATGGTTACGGTATTAAGAAAGA
AAATTTGGCTCGTGTTACAGAAGCCTTTTATACAACGAAACAAGATAAGATTGGTTTGGGACTTACGGTGGCGAATCGGC
TTGTTACGGAGCAGCATCTTGGTGAATTACATATTTCAAGTGAAAGAGATATTGGAACTAGAATAGATATCATTCTCCCG
AAACAACGTGGAAATAATGAAATCCAAGTGGGAGAAAAGCTAGGAGTTACCATATGA

Upstream 100 bases:

>100_bases
GATTTACCTCAAATGTTCGATTTCTCTTTGTTTGTCTAAGAAAATCATTTATTATAATAAATGGTATTACTTCGAGATGT
TTTTTTGAAGGGGTGTTGAA

Downstream 100 bases:

>100_bases
ATAAAGACGGTATATTTAAAAATGAAGAAATAAAGGCGCTGAAAATATTTTTAAGTTTATTTTTCATTATATTTTTTGTA
TACGATCTTGCCTACGAATT

Product: sensor histidine kinase

Products: NA

Alternate protein names: Sensor histidine kinase E [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKDSFLSYKEEERNAKILLWVLYVIVVSYQIFYAIVLENKSLTDKGYSILWQVICGTAILGVNVYLIKKEKANFVKYACV
FAYLGIEIANILSYMLYNEAAFDGGNIIEIILIFFVPIFLNKKYFVFVLSTIVVKYVIYLFVLKEVKGFMFLIMYTLVLI
AAYIILSRFIQYLSAVKESIKVASESQKLAVIGKMAATVGHEIKNPLASLKGFTQLQREKHGEDPIYKQMIFEIENMNNM
ISELMEVATCKPSIYKKHNIGEIVLQAVAILREKMNECSVQLISNVEENIIEAECDERKMRGVFLYVIKNALEAMEQGGT
LELRLENKGQDYVMLSVIDNGYGIKKENLARVTEAFYTTKQDKIGLGLTVANRLVTEQHLGELHISSERDIGTRIDIILP
KQRGNNEIQVGEKLGVTI

Sequences:

>Translated_418_residues
MKDSFLSYKEEERNAKILLWVLYVIVVSYQIFYAIVLENKSLTDKGYSILWQVICGTAILGVNVYLIKKEKANFVKYACV
FAYLGIEIANILSYMLYNEAAFDGGNIIEIILIFFVPIFLNKKYFVFVLSTIVVKYVIYLFVLKEVKGFMFLIMYTLVLI
AAYIILSRFIQYLSAVKESIKVASESQKLAVIGKMAATVGHEIKNPLASLKGFTQLQREKHGEDPIYKQMIFEIENMNNM
ISELMEVATCKPSIYKKHNIGEIVLQAVAILREKMNECSVQLISNVEENIIEAECDERKMRGVFLYVIKNALEAMEQGGT
LELRLENKGQDYVMLSVIDNGYGIKKENLARVTEAFYTTKQDKIGLGLTVANRLVTEQHLGELHISSERDIGTRIDIILP
KQRGNNEIQVGEKLGVTI
>Mature_418_residues
MKDSFLSYKEEERNAKILLWVLYVIVVSYQIFYAIVLENKSLTDKGYSILWQVICGTAILGVNVYLIKKEKANFVKYACV
FAYLGIEIANILSYMLYNEAAFDGGNIIEIILIFFVPIFLNKKYFVFVLSTIVVKYVIYLFVLKEVKGFMFLIMYTLVLI
AAYIILSRFIQYLSAVKESIKVASESQKLAVIGKMAATVGHEIKNPLASLKGFTQLQREKHGEDPIYKQMIFEIENMNNM
ISELMEVATCKPSIYKKHNIGEIVLQAVAILREKMNECSVQLISNVEENIIEAECDERKMRGVFLYVIKNALEAMEQGGT
LELRLENKGQDYVMLSVIDNGYGIKKENLARVTEAFYTTKQDKIGLGLTVANRLVTEQHLGELHISSERDIGTRIDIILP
KQRGNNEIQVGEKLGVTI

Specific function: Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=25.8823529411765, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=26.2548262548263, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790300, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47582; Mature: 47582

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50109 HIS_KIN ; PS00838 INTERLEUKIN_4_13

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSFLSYKEEERNAKILLWVLYVIVVSYQIFYAIVLENKSLTDKGYSILWQVICGTAIL
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHH
GVNVYLIKKEKANFVKYACVFAYLGIEIANILSYMLYNEAAFDGGNIIEIILIFFVPIFL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NKKYFVFVLSTIVVKYVIYLFVLKEVKGFMFLIMYTLVLIAAYIILSRFIQYLSAVKESI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVASESQKLAVIGKMAATVGHEIKNPLASLKGFTQLQREKHGEDPIYKQMIFEIENMNNM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ISELMEVATCKPSIYKKHNIGEIVLQAVAILREKMNECSVQLISNVEENIIEAECDERKM
HHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVFLYVIKNALEAMEQGGTLELRLENKGQDYVMLSVIDNGYGIKKENLARVTEAFYTTK
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC
QDKIGLGLTVANRLVTEQHLGELHISSERDIGTRIDIILPKQRGNNEIQVGEKLGVTI
CCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKDSFLSYKEEERNAKILLWVLYVIVVSYQIFYAIVLENKSLTDKGYSILWQVICGTAIL
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHH
GVNVYLIKKEKANFVKYACVFAYLGIEIANILSYMLYNEAAFDGGNIIEIILIFFVPIFL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NKKYFVFVLSTIVVKYVIYLFVLKEVKGFMFLIMYTLVLIAAYIILSRFIQYLSAVKESI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVASESQKLAVIGKMAATVGHEIKNPLASLKGFTQLQREKHGEDPIYKQMIFEIENMNNM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ISELMEVATCKPSIYKKHNIGEIVLQAVAILREKMNECSVQLISNVEENIIEAECDERKM
HHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVFLYVIKNALEAMEQGGTLELRLENKGQDYVMLSVIDNGYGIKKENLARVTEAFYTTK
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC
QDKIGLGLTVANRLVTEQHLGELHISSERDIGTRIDIILPKQRGNNEIQVGEKLGVTI
CCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]