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The map label for this gene is glcR [H]

Identifier: 118479901

GI number: 118479901

Start: 4565056

End: 4565829

Strand: Reverse

Name: glcR [H]

Synonym: BALH_4345

Alternate gene names: 118479901

Gene position: 4565829-4565056 (Counterclockwise)

Preceding gene: 118479903

Following gene: 118479900

Centisome position: 86.85

GC content: 32.56

Gene sequence:

>774_bases
ATGGGTGAGAGTATGAATCAAGAGGAACGTTTAATAAAAATAATAGAGTATTTGAATCAACATAGGACGATGAGCTTGAA
GATAATGTGTGAGCTATTTCAAGTCTCCAGAGATACAGCAAGAAGAGATATTGTAAAGTTAACAAATGAAACAACAATAG
TACGAACCCATGGTGGTGTAGCTTTATCATCTTTCCACCATAAAATATCGGATTATGTAAATCGTGAGGAAAAAGAAATT
GAATATAAGGTATCTATTGGAAAGCGAGCTGCTTCTTTTGTAGGAGATAATGAAGTGATTTATCTTGATGTTTCAACAAC
TGTTAACTGTATGGCTTCATTTTTGACAGCAAGTAACATAACGGTTGTTACAAATTCAATTGATACAGTAAATCATTTAA
TGGATATGGAGAATGTAAAGATTCATATTTTAGGTGGAGAATTAAATAAACACTCACGTTATATGACGGGTTTTTCTGCA
ATGGAGAAACTAAAAGATTATCATTTTGATAAAGTTTTTATTGGATCACCCGGTCTTACAGAAGATGGTGTCTATTATGC
GTATGAGGAAGATATTCATTTTAAGCGTCAAATTGTTAAACAAACAAATGAAGTGTTTTTACTTGCCGATGAGACAAAAA
TGAATCAACGTCAAAACTTTAAGGCGCTGTCATTAGAATCGATAGATACAATTATTACGAATGATGTTATTCCTGGCGAT
TTAGAAAGAGTAGTGAAAGAATATGGAATTGAGCTAATCGTTGGAGTGAAGTAA

Upstream 100 bases:

>100_bases
GCATTTTCTCACTCCTGTCTTAAGTTATTTTAAGGTTTATTTAAGTGTTTTTGTTGTGTTATACTTAAAATAACTTAAAA
TAACTTAAAAGTAAATAAAA

Downstream 100 bases:

>100_bases
AGGGGGACGTAAAAATGAAGGGGATTATATTTGATATTGATGGAACGATGTTAGATACGGAAAAAGCAGTTTTATATTCA
TTACAGAGAGCGTTGCGAGA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MGESMNQEERLIKIIEYLNQHRTMSLKIMCELFQVSRDTARRDIVKLTNETTIVRTHGGVALSSFHHKISDYVNREEKEI
EYKVSIGKRAASFVGDNEVIYLDVSTTVNCMASFLTASNITVVTNSIDTVNHLMDMENVKIHILGGELNKHSRYMTGFSA
MEKLKDYHFDKVFIGSPGLTEDGVYYAYEEDIHFKRQIVKQTNEVFLLADETKMNQRQNFKALSLESIDTIITNDVIPGD
LERVVKEYGIELIVGVK

Sequences:

>Translated_257_residues
MGESMNQEERLIKIIEYLNQHRTMSLKIMCELFQVSRDTARRDIVKLTNETTIVRTHGGVALSSFHHKISDYVNREEKEI
EYKVSIGKRAASFVGDNEVIYLDVSTTVNCMASFLTASNITVVTNSIDTVNHLMDMENVKIHILGGELNKHSRYMTGFSA
MEKLKDYHFDKVFIGSPGLTEDGVYYAYEEDIHFKRQIVKQTNEVFLLADETKMNQRQNFKALSLESIDTIITNDVIPGD
LERVVKEYGIELIVGVK
>Mature_256_residues
GESMNQEERLIKIIEYLNQHRTMSLKIMCELFQVSRDTARRDIVKLTNETTIVRTHGGVALSSFHHKISDYVNREEKEIE
YKVSIGKRAASFVGDNEVIYLDVSTTVNCMASFLTASNITVVTNSIDTVNHLMDMENVKIHILGGELNKHSRYMTGFSAM
EKLKDYHFDKVFIGSPGLTEDGVYYAYEEDIHFKRQIVKQTNEVFLLADETKMNQRQNFKALSLESIDTIITNDVIPGDL
ERVVKEYGIELIVGVK

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=258, Percent_Identity=31.0077519379845, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=27.6, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=26.4, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788069, Length=259, Percent_Identity=26.2548262548263, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790753, Length=258, Percent_Identity=26.3565891472868, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082344, Length=238, Percent_Identity=24.3697478991597, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=25.3275109170306, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=232, Percent_Identity=22.8448275862069, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29397; Mature: 29266

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESMNQEERLIKIIEYLNQHRTMSLKIMCELFQVSRDTARRDIVKLTNETTIVRTHGGV
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
ALSSFHHKISDYVNREEKEIEYKVSIGKRAASFVGDNEVIYLDVSTTVNCMASFLTASNI
EHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCE
TVVTNSIDTVNHLMDMENVKIHILGGELNKHSRYMTGFSAMEKLKDYHFDKVFIGSPGLT
EEEECCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCC
EDGVYYAYEEDIHFKRQIVKQTNEVFLLADETKMNQRQNFKALSLESIDTIITNDVIPGD
CCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEECHHHHHHHHHCCCCCCH
LERVVKEYGIELIVGVK
HHHHHHHCCCEEEEECC
>Mature Secondary Structure 
GESMNQEERLIKIIEYLNQHRTMSLKIMCELFQVSRDTARRDIVKLTNETTIVRTHGGV
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
ALSSFHHKISDYVNREEKEIEYKVSIGKRAASFVGDNEVIYLDVSTTVNCMASFLTASNI
EHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCE
TVVTNSIDTVNHLMDMENVKIHILGGELNKHSRYMTGFSAMEKLKDYHFDKVFIGSPGLT
EEEECCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCC
EDGVYYAYEEDIHFKRQIVKQTNEVFLLADETKMNQRQNFKALSLESIDTIITNDVIPGD
CCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEECHHHHHHHHHCCCCCCH
LERVVKEYGIELIVGVK
HHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]