Click here to switch to the map view.

The map label for this gene is acuC [H]

Identifier: 118479808

GI number: 118479808

Start: 4468595

End: 4469788

Strand: Direct

Name: acuC [H]

Synonym: BALH_4245

Alternate gene names: 118479808

Gene position: 4468595-4469788 (Clockwise)

Preceding gene: 118479807

Following gene: 118479809

Centisome position: 85.0

GC content: 42.88

Gene sequence:

>1194_bases
ATGGCCGAACATTATGGGGATGCAAGCATGAGTAGCGCGTTTATTTATTCGGATGACTTTCGGGGCTATTCGTTTAGCCC
TGATCATCCTTTTAACCAACTGCGCGTCACACTTACGTATGATTTATTACAAAAGGGCGGTTTTATCTCTCCTTCTCAAA
TCATCTCACCACGGATGGCTACAGATGAAGAGATTGCCTACATTCATACAGAGGAGTACATAAATGCGGTAAAACGTGCT
GGAGAAGGAAAGTTAGAAAAATCAATTGCGATGACATATGGACTCGGAACAGAAGATACACCGATGTTTCCGAATATGCA
CGAAGCAAGCGCATTACTCGTTGGTGGTACGTTAACAGCTGTCGATGCTGTTCTTTCTGGGAAAGTAAAACACGCACTTA
ACTTAGGAGGCGGCTTACATCATGGCTTCCGTGGCAAAGCATCTGGCTTTTGCATTTATAACGATAGTTCCATCGCAATG
AAATATATTCAAAAGAAGTACGGTTTACGCGTTTTATATATTGATACAGATGCTCATCACGGTGATGGTGTACAGTGGTC
CTTTTATGACGATCCTAACGTATGCACCATTTCACTACATGAAACTGGTCGATATTTATTCCCTGGAACTGGTGCTGTAA
ATGAACGCGGACAAGGTAATGGCTATAGTTACTCTTTTAACGTTCCACTCGATGCTTTTACAGAAGACGAATCTTTCTTA
GATTCCTATCGAACTGTCGTAAAAGAAGTGGCCGCATACTTTAAACCGGATATTATTTTAACGCAAAATGGCGCTGACGC
ACATTATTACGACCCACTTACACACCTTTGCGCAACGATGAATATTTACCGTGAAATACCGAAGCTTGCTCGCGAAATCG
CTAACGAATATTGCGAAGGTCGCTGGATTGCTGTCGGCGGCGGTGGCTATGACCACTGGCGCGTCGTCCCAAGAGCTTGG
GCACTCATTTGGCTCGAAATGAACAACATCCAAAACATCTCAGGTTATCTCCCTCCAGAATGGATTGACGCTTGGAAAGG
ACAAGCTGAAACAGAACTTCCCCTCACATGGGAAGATCCAGACAACATGTATAAACCTATCCCCCGCAAACCAGAAATTG
AAGAAAAGAACGCATTAACTGTAGCGAAATCCCTTGAAATTATTCGGAATAATATGAAAAAATCTTTGTACTAA

Upstream 100 bases:

>100_bases
CAGCAAAAGATGAGAATGATAAAGTACTCGTTTTCCGCATTCAAACGATGAATCCTCTAAAAGTGATTGATGCACTTGAA
GCAGAAGGCTACCGCGTATT

Downstream 100 bases:

>100_bases
ACGAAAAGGAGGCTCGTTTTTGAATAGCCTCCTTTTATTTAAAGCCTGCTATTATTGTCGATTTCTGTCGGTAAGTCGAT
ATATTTTAATAATCGCTGAT

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAEHYGDASMSSAFIYSDDFRGYSFSPDHPFNQLRVTLTYDLLQKGGFISPSQIISPRMATDEEIAYIHTEEYINAVKRA
GEGKLEKSIAMTYGLGTEDTPMFPNMHEASALLVGGTLTAVDAVLSGKVKHALNLGGGLHHGFRGKASGFCIYNDSSIAM
KYIQKKYGLRVLYIDTDAHHGDGVQWSFYDDPNVCTISLHETGRYLFPGTGAVNERGQGNGYSYSFNVPLDAFTEDESFL
DSYRTVVKEVAAYFKPDIILTQNGADAHYYDPLTHLCATMNIYREIPKLAREIANEYCEGRWIAVGGGGYDHWRVVPRAW
ALIWLEMNNIQNISGYLPPEWIDAWKGQAETELPLTWEDPDNMYKPIPRKPEIEEKNALTVAKSLEIIRNNMKKSLY

Sequences:

>Translated_397_residues
MAEHYGDASMSSAFIYSDDFRGYSFSPDHPFNQLRVTLTYDLLQKGGFISPSQIISPRMATDEEIAYIHTEEYINAVKRA
GEGKLEKSIAMTYGLGTEDTPMFPNMHEASALLVGGTLTAVDAVLSGKVKHALNLGGGLHHGFRGKASGFCIYNDSSIAM
KYIQKKYGLRVLYIDTDAHHGDGVQWSFYDDPNVCTISLHETGRYLFPGTGAVNERGQGNGYSYSFNVPLDAFTEDESFL
DSYRTVVKEVAAYFKPDIILTQNGADAHYYDPLTHLCATMNIYREIPKLAREIANEYCEGRWIAVGGGGYDHWRVVPRAW
ALIWLEMNNIQNISGYLPPEWIDAWKGQAETELPLTWEDPDNMYKPIPRKPEIEEKNALTVAKSLEIIRNNMKKSLY
>Mature_396_residues
AEHYGDASMSSAFIYSDDFRGYSFSPDHPFNQLRVTLTYDLLQKGGFISPSQIISPRMATDEEIAYIHTEEYINAVKRAG
EGKLEKSIAMTYGLGTEDTPMFPNMHEASALLVGGTLTAVDAVLSGKVKHALNLGGGLHHGFRGKASGFCIYNDSSIAMK
YIQKKYGLRVLYIDTDAHHGDGVQWSFYDDPNVCTISLHETGRYLFPGTGAVNERGQGNGYSYSFNVPLDAFTEDESFLD
SYRTVVKEVAAYFKPDIILTQNGADAHYYDPLTHLCATMNIYREIPKLAREIANEYCEGRWIAVGGGGYDHWRVVPRAWA
LIWLEMNNIQNISGYLPPEWIDAWKGQAETELPLTWEDPDNMYKPIPRKPEIEEKNALTVAKSLEIIRNNMKKSLY

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=314, Percent_Identity=32.1656050955414, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI13128860, Length=310, Percent_Identity=32.5806451612903, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI8923769, Length=294, Percent_Identity=32.9931972789116, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI293336691, Length=268, Percent_Identity=34.3283582089552, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI20070354, Length=312, Percent_Identity=30.7692307692308, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI262073092, Length=206, Percent_Identity=35.4368932038835, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI30795202, Length=332, Percent_Identity=29.5180722891566, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI30795204, Length=315, Percent_Identity=31.1111111111111, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI17158039, Length=333, Percent_Identity=30.03003003003, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI153085395, Length=268, Percent_Identity=32.8358208955224, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI226529806, Length=233, Percent_Identity=33.4763948497854, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI148539870, Length=263, Percent_Identity=31.5589353612167, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI169234807, Length=263, Percent_Identity=31.5589353612167, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI62750349, Length=309, Percent_Identity=31.3915857605178, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI62750347, Length=309, Percent_Identity=31.3915857605178, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI13128864, Length=290, Percent_Identity=30, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI262073088, Length=197, Percent_Identity=35.5329949238579, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI217272877, Length=259, Percent_Identity=26.6409266409266, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI209862883, Length=253, Percent_Identity=26.4822134387352, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=309, Percent_Identity=33.9805825242718, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17561978, Length=314, Percent_Identity=33.1210191082803, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17534739, Length=313, Percent_Identity=30.6709265175719, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI193209491, Length=305, Percent_Identity=28.8524590163934, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540334, Length=310, Percent_Identity=27.4193548387097, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI193206283, Length=310, Percent_Identity=27.4193548387097, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17540332, Length=310, Percent_Identity=27.4193548387097, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25154020, Length=329, Percent_Identity=24.3161094224924, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25154022, Length=329, Percent_Identity=24.6200607902736, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193207430, Length=286, Percent_Identity=23.7762237762238, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537347, Length=225, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323999, Length=321, Percent_Identity=32.0872274143302, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321244, Length=325, Percent_Identity=32.3076923076923, Blast_Score=169, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324307, Length=306, Percent_Identity=30.3921568627451, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325325, Length=235, Percent_Identity=25.9574468085106, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644244, Length=314, Percent_Identity=32.1656050955414, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24657891, Length=310, Percent_Identity=31.9354838709677, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24642142, Length=289, Percent_Identity=30.1038062283737, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24642144, Length=289, Percent_Identity=30.1038062283737, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24642146, Length=289, Percent_Identity=30.1038062283737, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281360899, Length=289, Percent_Identity=30.1038062283737, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24641720, Length=311, Percent_Identity=27.9742765273312, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360801, Length=311, Percent_Identity=27.9742765273312, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360799, Length=310, Percent_Identity=28.0645161290323, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24649807, Length=255, Percent_Identity=24.7058823529412, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44636; Mature: 44505

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHYGDASMSSAFIYSDDFRGYSFSPDHPFNQLRVTLTYDLLQKGGFISPSQIISPRMA
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCHHHHCCCCCC
TDEEIAYIHTEEYINAVKRAGEGKLEKSIAMTYGLGTEDTPMFPNMHEASALLVGGTLTA
CCCCEEEEEHHHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCEEEECCHHHH
VDAVLSGKVKHALNLGGGLHHGFRGKASGFCIYNDSSIAMKYIQKKYGLRVLYIDTDAHH
HHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCC
GDGVQWSFYDDPNVCTISLHETGRYLFPGTGAVNERGQGNGYSYSFNVPLDAFTEDESFL
CCCEEEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
DSYRTVVKEVAAYFKPDIILTQNGADAHYYDPLTHLCATMNIYREIPKLAREIANEYCEG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RWIAVGGGGYDHWRVVPRAWALIWLEMNNIQNISGYLPPEWIDAWKGQAETELPLTWEDP
EEEEECCCCCCHHEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCEEECCC
DNMYKPIPRKPEIEEKNALTVAKSLEIIRNNMKKSLY
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEHYGDASMSSAFIYSDDFRGYSFSPDHPFNQLRVTLTYDLLQKGGFISPSQIISPRMA
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCCHHHHCCCCCC
TDEEIAYIHTEEYINAVKRAGEGKLEKSIAMTYGLGTEDTPMFPNMHEASALLVGGTLTA
CCCCEEEEEHHHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCEEEECCHHHH
VDAVLSGKVKHALNLGGGLHHGFRGKASGFCIYNDSSIAMKYIQKKYGLRVLYIDTDAHH
HHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCC
GDGVQWSFYDDPNVCTISLHETGRYLFPGTGAVNERGQGNGYSYSFNVPLDAFTEDESFL
CCCEEEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
DSYRTVVKEVAAYFKPDIILTQNGADAHYYDPLTHLCATMNIYREIPKLAREIANEYCEG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RWIAVGGGGYDHWRVVPRAWALIWLEMNNIQNISGYLPPEWIDAWKGQAETELPLTWEDP
EEEEECCCCCCHHEECCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCEEECCC
DNMYKPIPRKPEIEEKNALTVAKSLEIIRNNMKKSLY
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]