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The map label for this gene is spoU [H]

Identifier: 118479709

GI number: 118479709

Start: 4365802

End: 4366599

Strand: Reverse

Name: spoU [H]

Synonym: BALH_4143

Alternate gene names: 118479709

Gene position: 4366599-4365802 (Counterclockwise)

Preceding gene: 118479716

Following gene: 162382771

Centisome position: 83.06

GC content: 38.6

Gene sequence:

>798_bases
ATGATAAGACAAGAAGAGAGGGAAATACATATTATGAAAAACATTGATTCAGTACAAAATCCGCGTGTGAAGCAGTGGAA
AAAGCTGCAAACGAAAAAAGAGCGCGATAAAAAAGGTTTATTTTTTGTAGAAGGATTCCATTTAGTAGAGGAAGCTTTAA
AAGCAGGAGTTGTAACAGAACTTATCGTTTCAGATCAGACAGACCTTCCGAAAGATTGGACAGTTAATGATGTAGAAATG
TATATCGTACCGGAAGCAATCGTAAAAGTACTTCGTGAAACAGAAACGACACAAGGTGTATTTGCTGTTTGTGAAAAGCA
TGAGAAGGAAGTGGCTCTTGCTGATGGGAAGTTTCTTTTATTAGATGGCCTGCAAGATCCAGGTAACTTAGGGACAATTA
TTCGTACAGCTGATGCAGCTGGTATTCATGCCGTTGTGCTTGGAGAAGGTTGTGTTGATGTTTATAATAGTAAAGTACTC
CGTTCTACACAAGGTTCTATTTTCCACTTACCAATTGTAAAAGGGAACTTAGAAGAATGGGTAGACAAGCTAAAAGAAAA
TAACGTTCCTGTATATGGAACAGCTCTTGAAAATGGAGTTCCGTATGGGGAAGTAACACCAGCTGGTAGTTTTGCATTAA
TTGTAGGAAATGAAGGAAATGGCGTACGCCAAGAAATTCTTGCAAAAACGGATCAAAACTTGTATATTCCGATTTACGGC
GGGGCAGAATCATTAAATGTTGCAGTTGCAGCAGGGATTTTAACGTATTATTTGCAAAGCCCGGTTGCGAACCAATAA

Upstream 100 bases:

>100_bases
GCGTAAATTAAAACTCATTGTTTTCACCTCTTCTTCAGAATTGAAACTGACGTTAGTTTTTGTTCTTTTTTATGTAAATA
TGTATGAAAAATAGGCTATA

Downstream 100 bases:

>100_bases
AAAACTTCTTATAATAAGTTGAAGTGCATTATATTAAAAGTTAAATAACGAAAAACGTTGATAGAGAAGAGTAGCTTACA
AAATCGCCATATAGGGAGAG

Product: 23S rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIRQEEREIHIMKNIDSVQNPRVKQWKKLQTKKERDKKGLFFVEGFHLVEEALKAGVVTELIVSDQTDLPKDWTVNDVEM
YIVPEAIVKVLRETETTQGVFAVCEKHEKEVALADGKFLLLDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDVYNSKVL
RSTQGSIFHLPIVKGNLEEWVDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLYIPIYG
GAESLNVAVAAGILTYYLQSPVANQ

Sequences:

>Translated_265_residues
MIRQEEREIHIMKNIDSVQNPRVKQWKKLQTKKERDKKGLFFVEGFHLVEEALKAGVVTELIVSDQTDLPKDWTVNDVEM
YIVPEAIVKVLRETETTQGVFAVCEKHEKEVALADGKFLLLDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDVYNSKVL
RSTQGSIFHLPIVKGNLEEWVDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLYIPIYG
GAESLNVAVAAGILTYYLQSPVANQ
>Mature_265_residues
MIRQEEREIHIMKNIDSVQNPRVKQWKKLQTKKERDKKGLFFVEGFHLVEEALKAGVVTELIVSDQTDLPKDWTVNDVEM
YIVPEAIVKVLRETETTQGVFAVCEKHEKEVALADGKFLLLDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDVYNSKVL
RSTQGSIFHLPIVKGNLEEWVDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLYIPIYG
GAESLNVAVAAGILTYYLQSPVANQ

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI8922534, Length=291, Percent_Identity=27.8350515463918, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1790623, Length=148, Percent_Identity=36.4864864864865, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790083, Length=152, Percent_Identity=29.6052631578947, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666840, Length=284, Percent_Identity=27.8169014084507, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29185; Mature: 29185

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQEEREIHIMKNIDSVQNPRVKQWKKLQTKKERDKKGLFFVEGFHLVEEALKAGVVTE
CCCCCCHHHHEECCCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCHHHH
LIVSDQTDLPKDWTVNDVEMYIVPEAIVKVLRETETTQGVFAVCEKHEKEVALADGKFLL
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCEEE
LDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDVYNSKVLRSTQGSIFHLPIVKGNLEEW
EECCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHCCHHHHCCCCCEEEEEEEECCHHHH
VDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLYIPIYG
HHHHHHCCCCEEEEHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEC
GAESLNVAVAAGILTYYLQSPVANQ
CCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRQEEREIHIMKNIDSVQNPRVKQWKKLQTKKERDKKGLFFVEGFHLVEEALKAGVVTE
CCCCCCHHHHEECCCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCHHHH
LIVSDQTDLPKDWTVNDVEMYIVPEAIVKVLRETETTQGVFAVCEKHEKEVALADGKFLL
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCEEE
LDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDVYNSKVLRSTQGSIFHLPIVKGNLEEW
EECCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHCCHHHHCCCCCEEEEEEEECCHHHH
VDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLYIPIYG
HHHHHHCCCCEEEEHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEC
GAESLNVAVAAGILTYYLQSPVANQ
CCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]