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The map label for this gene is aqpZ [H]

Identifier: 118479659

GI number: 118479659

Start: 4308786

End: 4309451

Strand: Direct

Name: aqpZ [H]

Synonym: BALH_4090

Alternate gene names: 118479659

Gene position: 4308786-4309451 (Clockwise)

Preceding gene: 118479658

Following gene: 118479663

Centisome position: 81.96

GC content: 36.49

Gene sequence:

>666_bases
ATGTTAAAAAAAGCAATCGCTGAATTTATTGGTACATTTGTACTGGTATTATTCGGAACTGGAGTAGCTGTCATTGGCGG
CGGAATTGAAGGAATTGGGACATTAGGAATCGCTATGGCTTTCGGTCTATCTATTGTGGCTATGGCATATAGCATCGGAA
CAATTTCTGGATGTCACATTAACCCAGCAGTATCAGTAGCTATGTTCATCAACAAAAGAATGAACGCTATGGAACTTTGT
TATTATGTATTAGCTCAAATTTTAGGTGGTTTATTAGGAACTGCAACATTGGTAACAATTTTACAATCCGCTAAAACACC
TTTAGATAATTTAGGACAAAATGGTTTTGGAACTCTTGGTTTATCTGGAGCATTTCTAGTTGAATTTATTTTAACTTTCG
TATTCATTTTAGTAATCGTCGCTGTAACAGGTAAAAAAGGAAGTTCTTCTCTAGCAGGATTAGTAATTGGTTTCACATTA
GTTTTAGTCCACTTATTAGGTATTCCGTTAACTGGAACTTCTGTTAACCCAGCTCGTAGTATCGCACCAGCTTTATTCGC
TGGCGGAGAAGCACTTTCTCAACTATGGGTATTCATCGTTGCACCAATTCTTGGTGGTATCGTAGCAGCTATCGTAGGTA
AATTCATTTTAAATACTGAAAAATAA

Upstream 100 bases:

>100_bases
TTGTCCCCCTATTTCGCCTTATCAGAATAGTATTTCATTGGCTGTTTATACTAAAACCTATGTTATAATACGTTTCATGC
GCAATAATAGGAGGTAAATT

Downstream 100 bases:

>100_bases
AATTTTCAATATTTCTGAATAAAAAAAGGCGAGCCCTCATTATGAGGATGCTCGCTTTTTTACTCTTTCATTTTAGACTT
TAAATTTGTAACTAGTTGAT

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MLKKAIAEFIGTFVLVLFGTGVAVIGGGIEGIGTLGIAMAFGLSIVAMAYSIGTISGCHINPAVSVAMFINKRMNAMELC
YYVLAQILGGLLGTATLVTILQSAKTPLDNLGQNGFGTLGLSGAFLVEFILTFVFILVIVAVTGKKGSSSLAGLVIGFTL
VLVHLLGIPLTGTSVNPARSIAPALFAGGEALSQLWVFIVAPILGGIVAAIVGKFILNTEK

Sequences:

>Translated_221_residues
MLKKAIAEFIGTFVLVLFGTGVAVIGGGIEGIGTLGIAMAFGLSIVAMAYSIGTISGCHINPAVSVAMFINKRMNAMELC
YYVLAQILGGLLGTATLVTILQSAKTPLDNLGQNGFGTLGLSGAFLVEFILTFVFILVIVAVTGKKGSSSLAGLVIGFTL
VLVHLLGIPLTGTSVNPARSIAPALFAGGEALSQLWVFIVAPILGGIVAAIVGKFILNTEK
>Mature_221_residues
MLKKAIAEFIGTFVLVLFGTGVAVIGGGIEGIGTLGIAMAFGLSIVAMAYSIGTISGCHINPAVSVAMFINKRMNAMELC
YYVLAQILGGLLGTATLVTILQSAKTPLDNLGQNGFGTLGLSGAFLVEFILTFVFILVIVAVTGKKGSSSLAGLVIGFTL
VLVHLLGIPLTGTSVNPARSIAPALFAGGEALSQLWVFIVAPILGGIVAAIVGKFILNTEK

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4502179, Length=222, Percent_Identity=37.8378378378378, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI6912506, Length=218, Percent_Identity=35.3211009174312, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4502183, Length=223, Percent_Identity=36.7713004484305, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI4502181, Length=218, Percent_Identity=35.7798165137615, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI4755125, Length=217, Percent_Identity=35.9447004608295, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI37694062, Length=224, Percent_Identity=33.0357142857143, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI86792455, Length=219, Percent_Identity=33.7899543378995, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI157266307, Length=240, Percent_Identity=32.0833333333333, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4826645, Length=247, Percent_Identity=33.1983805668016, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4502187, Length=244, Percent_Identity=30.7377049180328, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI45446752, Length=191, Percent_Identity=32.4607329842932, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22538420, Length=235, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787101, Length=209, Percent_Identity=44.0191387559809, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790362, Length=246, Percent_Identity=27.6422764227642, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71993722, Length=230, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17531429, Length=239, Percent_Identity=30.9623430962343, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531431, Length=239, Percent_Identity=30.9623430962343, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558372, Length=235, Percent_Identity=28.936170212766, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI212646268, Length=272, Percent_Identity=23.5294117647059, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994009, Length=239, Percent_Identity=28.0334728033473, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321054, Length=211, Percent_Identity=28.9099526066351, Blast_Score=68, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24652747, Length=222, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45551084, Length=222, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19922038, Length=223, Percent_Identity=34.0807174887892, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652751, Length=223, Percent_Identity=34.0807174887892, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24762344, Length=233, Percent_Identity=28.3261802575107, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24762346, Length=233, Percent_Identity=28.3261802575107, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24762348, Length=233, Percent_Identity=28.3261802575107, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20130305, Length=233, Percent_Identity=28.3261802575107, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550503, Length=227, Percent_Identity=27.7533039647577, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17136672, Length=186, Percent_Identity=27.9569892473118, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24762342, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922828, Length=223, Percent_Identity=27.3542600896861, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 22585; Mature: 22585

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKAIAEFIGTFVLVLFGTGVAVIGGGIEGIGTLGIAMAFGLSIVAMAYSIGTISGCHI
CCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NPAVSVAMFINKRMNAMELCYYVLAQILGGLLGTATLVTILQSAKTPLDNLGQNGFGTLG
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
LSGAFLVEFILTFVFILVIVAVTGKKGSSSLAGLVIGFTLVLVHLLGIPLTGTSVNPARS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IAPALFAGGEALSQLWVFIVAPILGGIVAAIVGKFILNTEK
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKKAIAEFIGTFVLVLFGTGVAVIGGGIEGIGTLGIAMAFGLSIVAMAYSIGTISGCHI
CCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NPAVSVAMFINKRMNAMELCYYVLAQILGGLLGTATLVTILQSAKTPLDNLGQNGFGTLG
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
LSGAFLVEFILTFVFILVIVAVTGKKGSSSLAGLVIGFTLVLVHLLGIPLTGTSVNPARS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IAPALFAGGEALSQLWVFIVAPILGGIVAAIVGKFILNTEK
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]