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The map label for this gene is clpX [H]

Identifier: 118479638

GI number: 118479638

Start: 4287448

End: 4288782

Strand: Reverse

Name: clpX [H]

Synonym: BALH_4065

Alternate gene names: 118479638

Gene position: 4288782-4287448 (Counterclockwise)

Preceding gene: 118479639

Following gene: 118479637

Centisome position: 81.58

GC content: 37.75

Gene sequence:

>1335_bases
ATGTATTTACATACGATACATTTATCGTGTACATACGAAGGCAAGAGGTTAGCACTTTGTAAGGGGTGTGAAAATATGTT
TAAATTTAATGATGAAAAAGGGCAATTAAAATGTTCTTTCTGTGGTAAAACACAAACGCAAGTCCGAAAGTTAGTTGCAG
GTCCAGGTGTTTACATTTGTGACGAGTGTATCGAACTTTGTACTGAAATTGTACAAGAGGAGCTTGCGAAAGACGAAGAA
GTAGAATTCAAAGATGTACCGAAACCGGTAGAAATTCGTGAAATTTTAGATGAGTATGTCATCGGACAAGATAACGCGAA
AAAAGCACTAGCGGTAGCGGTATATAACCATTACAAACGCATTAATTCTAACAGCAAAATTGATGATGTAGAATTAGCGA
AGAGTAATATCGCACTTATCGGGCCAACAGGTAGTGGTAAAACATTACTGGCACAAACGTTAGCGCGTATTTTAAATGTT
CCATTTGCAATCGCGGACGCAACATCTTTAACTGAAGCTGGATACGTTGGGGAAGATGTAGAAAACATCTTACTTAAATT
AATCCAAGCAGCGGATTATGATGTAGAAAAAGCGGAAAAAGGAATCATTTATATTGATGAGATTGATAAAGTGGCACGTA
AGTCCGAAAATCCATCAATTACACGTGATGTATCTGGTGAAGGTGTGCAGCAGGCACTTCTGAAAATTTTAGAAGGTACT
GTAGCAAGCGTTCCACCTCAAGGTGGTCGTAAGCATCCACACCAAGAGTTTATTCAAATTGATACAACGAATATCTTATT
CATCTGTGGTGGAGCGTTTGATGGCATCGAGCCAATTATTAAACGTCGTCTTGGTGAAAAAGTAATTGGATTTGGTTCTG
AGAAGAAAAATGCTGATGTAAATGAGAAGCATGTTTTATCTCACGTATTACCAGAGGACCTTTTAAGATTTGGTTTAATT
CCAGAGTTTATCGGTCGTCTTCCAGTTATTGCGAACCTAGAGCCACTTGATGAAGATGCTCTTGTTGATATTTTAACGAA
ACCGAAAAATGCACTTGTTAAGCAATTCCAAAAACTATTGGAGCTTGACGATGTTGAGTTAGAGTTTGAAGAAGGTGCAC
TAATTGAAATTGCGAAAAAAGCAATTGAACGTAAAACAGGTGCTCGTGGACTTCGTTCTATTATTGAAGGCTTAATGCTT
GAGGTAATGTTCGAGCTACCATCTCGCAAAGATATCGAGAAGTGTATTCTTACAAAAGAAACAGTAGCTGATAATGCAGC
ACCAAAATTGGTGTTACAAGACGGTACTGTACTTGATACAAAAACATCTGCATAA

Upstream 100 bases:

>100_bases
CTTAATAAGTCGAATATACATATTTCAAAAGTTTTAAAAACTTTTTATTTGTACATAACTAGTCATATTATTTGTATTTC
TCGCCACGTAGTGACATAAT

Downstream 100 bases:

>100_bases
TGCGAAGGAGAAACAGCAATTTTTATAATTGCTGTTTTTCTTTATGTTTAGCTATGTTCCTCCGCGGAAATACTAAGAGA
TAAAACATTGCGGGAGGAAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MYLHTIHLSCTYEGKRLALCKGCENMFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEE
VEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNV
PFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGT
VASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLI
PEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLML
EVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA

Sequences:

>Translated_444_residues
MYLHTIHLSCTYEGKRLALCKGCENMFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEE
VEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNV
PFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGT
VASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLI
PEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLML
EVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA
>Mature_444_residues
MYLHTIHLSCTYEGKRLALCKGCENMFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEE
VEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNV
PFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGT
VASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLI
PEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLML
EVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=51.0510510510511, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786642, Length=409, Percent_Identity=61.6136919315403, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=45.6310679611651, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.9807073954984, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=45.9807073954984, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=427, Percent_Identity=36.768149882904, Blast_Score=247, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=38.8461538461538, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=38.8349514563107, Blast_Score=259, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=49.2163009404389, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=49.2163009404389, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49066; Mature: 49066

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLHTIHLSCTYEGKRLALCKGCENMFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYIC
CEEEEEEEEEEECCCEEHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHH
DECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKR
HHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
INSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDV
CCCCCCCCHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCHHH
ENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGT
HHHHHHHHHHCCCCHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCH
VASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADV
HHCCCCCCCCCCCHHHHEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
NEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLL
CHHHHHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKE
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TVADNAAPKLVLQDGTVLDTKTSA
HHHCCCCCEEEEECCEEECCCCCC
>Mature Secondary Structure
MYLHTIHLSCTYEGKRLALCKGCENMFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYIC
CEEEEEEEEEEECCCEEHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHH
DECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKR
HHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
INSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDV
CCCCCCCCHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCHHH
ENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGT
HHHHHHHHHHCCCCHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCH
VASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADV
HHCCCCCCCCCCCHHHHEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
NEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLL
CHHHHHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKE
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TVADNAAPKLVLQDGTVLDTKTSA
HHHCCCCCEEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA