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The map label for this gene is ydhC [C]

Identifier: 118478726

GI number: 118478726

Start: 3298086

End: 3299285

Strand: Reverse

Name: ydhC [C]

Synonym: BALH_3115

Alternate gene names: 118478726

Gene position: 3299285-3298086 (Counterclockwise)

Preceding gene: 118478728

Following gene: 118478725

Centisome position: 62.76

GC content: 35.58

Gene sequence:

>1200_bases
ATGAAAAAAGTCTCAGTACCATCACTTTTGTTAATGATTATTCTTGTCGCATTTCCGCAAATTAGTGAAACGATTTACAC
ACCGTCTTTACCTGACATTTCAAAGGCGCTACATGTAAGTAATAATGAGGTACAGTTAACACTTAGTGTGTATTTTGCCG
GATTTGCTTTAGGCGTATTTTTTATTGGATGGTTATCGGATATAATTGGTCGTCGACGGGCAATGTTACTTGGAATTGTT
GTATATGGCGTAGGGAGTTTCTTATGCTTTATTGCAAATTCCATTGAAGTTTTATTGGTAAGTCGTTTTATTCAAGCGTT
TGGAGCAAGTGCTGGATCTGTTGTGACACAAACGATTCTACGTGAAAGTGTAGAAGGGCATAAGAGGCATGTTATGTTTG
CTCAAATCTCGGCAGTCATTGCTTTTACACCAGCGATAGGACCGTTAATTGGTGGTTTTCTTGATCAAATGTTTGGATTT
AAAATCGTATTTTTAAGTTTAGTAGTTATGAGTGTCGGAATTTTGCTGTATACTTTTGTTTCCCTTCCGGAAACAAAGAC
GGACTCAATAACGAATAAAATAAATGTGTTTTCAGTCTTGAAGAGGTTAATTACAAATCCAAAAGTAGTAACATACGGGT
TATTAATTGGAGGAGCGAATGGTGTTTTATTTAGCTATTATGCAGAAGCGCCATTTATCTTTATTGAATACTTTCAGTTA
TCGCCTAGTATGTATGGATTTTTAGGAATCGTTGTTGCTTCTGCTTCTATTATTGGAGCGAAAGTTTCCAAACGATTGCT
TGCCACGTATAAACCAGAGAAAATTATATATATCGGTTGTCTTGTAATGACAGGGGGAGCTATTCTTTTGTCTGTTATTA
CTTCACTGGGATCAAATCCAAACATTATATATATGATTGTATTTTTAGTAGCGATGTTTATTTTGCTATTAGGAATTGGA
GTAGCGTTGCCTAACTGTTTAAGTTTAGCATTAGTAGATTTTCAAGATGTTATTGGTACAGCCGGAGCATTGTTTAGCTT
AGGCTACTATGTAATAGTAACGATGACAATTTGGGGAATGAGCCAGCTGCATACGGGCTCGTTACTAGTGATGCCACTTT
ATTTCCTAGCTATAGTAGTTATCATGATGGTGTTTACTAAAGTGTTTATTTTAGGGAAACAAACTTCAAAGATGATTTAA

Upstream 100 bases:

>100_bases
TTGTTTTATGATCGAATTTCTATAATGGCCCCTCCCGTTCCGTAGCTAAGGAAAGTCTTTTTATTTCTGAGATTTTCAAA
GTTATAGGAGGGTATGAAAA

Downstream 100 bases:

>100_bases
ATATGAAATGGTAAAAGGGTCTCATTAAAAATGAGACCCTTTTATATTTTATCCCGCTATTTTGAGGTAGTAAGGTTCCT
GCCTCAAAATTGGGCTGGAC

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGILLYTFVSLPETKTDSITNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITSLGSNPNIIYMIVFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKMI

Sequences:

>Translated_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGILLYTFVSLPETKTDSITNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITSLGSNPNIIYMIVFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKMI
>Mature_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGILLYTFVSLPETKTDSITNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITSLGSNPNIIYMIVFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKMI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=324, Percent_Identity=25.3086419753086, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788509, Length=374, Percent_Identity=25.9358288770053, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082312, Length=326, Percent_Identity=25.7668711656442, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790146, Length=338, Percent_Identity=23.3727810650888, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787065, Length=262, Percent_Identity=25.1908396946565, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790794, Length=394, Percent_Identity=24.1116751269036, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324264, Length=164, Percent_Identity=29.8780487804878, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43280; Mature: 43280

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVF
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHH
FIGWLSDIIGRRRAMLLGIVVYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGFKIVFLSLVVMSVGILLYTFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPETKTDSITNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEHHCCCCEEEEEHHHH
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITSLGSNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
NIIYMIVFLVAMFILLLGIGVALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKMI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVF
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHH
FIGWLSDIIGRRRAMLLGIVVYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGFKIVFLSLVVMSVGILLYTFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPETKTDSITNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEHHCCCCEEEEEHHHH
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITSLGSNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
NIIYMIVFLVAMFILLLGIGVALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKMI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA