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The map label for this gene is bla

Identifier: 118478708

GI number: 118478708

Start: 3283233

End: 3284024

Strand: Reverse

Name: bla

Synonym: BALH_3094

Alternate gene names: NA

Gene position: 3284024-3283233 (Counterclockwise)

Preceding gene: 118478709

Following gene: 118478706

Centisome position: 62.47

GC content: 35.1

Gene sequence:

>792_bases
TTGAAAGAAAGGGTGGAGAAAATGAAAAATACATTATTAAAATTAGGGGTATGTGTTAGTTTACTAGGAATAACTCCAAT
TGTTAGTACAATTTCTTCTGTACAAGCAGAACGAACGGTAGAGCATAAAGTAATAAAAAATGAGACAGGAACTATTTCAA
TTTCTCAGTTAAACAAAAATGTTTGGGTTCATACGGAGTTAGGTTATTTTAACGGAGAAGCAGTTCCTTCGAACGGTTTA
ATCCTTAATACTTCTAAAGGATTAGTACTTGTCGATTCTTCTTGGGATGATAAGTTAACGAAGGAATTAATAGAGATGGC
AGAAAAGAAATTTAAGAAGCGTGTAACGGATGTTATTATTACACATGCACACGCTGATCGGATTGGCGGAATAAAAACGT
TGAAAGAAAAGGGCATTAAAGCTCATAGTACGGCATTGACTGCAGAACTAGCAAAGAAAAATGGATATGAAGAACCAATT
GGAGACTTACAAGCAATTACGAAATTGAAGTTTGGAAATATGAAAATAGAAACGTTTTATCCAGGGAAAGGACATACAGA
AGATAATATTGTCGTATGGTTATCACAATACAACATTTTAGCTGGAGGCTGTTTAGTGAAATCTGCGTCCGCGAAAGATT
TAGGAAACGTTGCTGATGCTTATGTAAATGAATGGTCTACATCGATTGAGAATGTGCTGACGCGATATAGAAATATAAAT
GCAGTAGTGCCTGGTCATGGGGAAGTAGGGGATAGAGGATTACTTTTACATACATTGGAATTGTTGAAATAA

Upstream 100 bases:

>100_bases
ATTTTGTACACTTTTTTTGTTAAATACATAAAAAATATGCAAGTAAAGATGGAACAAACACTGAAGATGAATTGTCTAAT
ATAGGTAATAAATATTTCGT

Downstream 100 bases:

>100_bases
AAAAGCGAGGAGAAACAAATTTCTCCTCGCTTTCTTCTAACTATATTTAAATGCGAAGCCTGCATACGTTACTGAGATTT
TAATTCCAAGTATACAAATA

Product: beta-lactamase II

Products: NA

Alternate protein names: Beta-lactamase II; Cephalosporinase; Penicillinase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKERVEKMKNTLLKLGVCVSLLGITPIVSTISSVQAERTVEHKVIKNETGTISISQLNKNVWVHTELGYFNGEAVPSNGL
ILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKRVTDVIITHAHADRIGGIKTLKEKGIKAHSTALTAELAKKNGYEEPI
GDLQAITKLKFGNMKIETFYPGKGHTEDNIVVWLSQYNILAGGCLVKSASAKDLGNVADAYVNEWSTSIENVLTRYRNIN
AVVPGHGEVGDRGLLLHTLELLK

Sequences:

>Translated_263_residues
MKERVEKMKNTLLKLGVCVSLLGITPIVSTISSVQAERTVEHKVIKNETGTISISQLNKNVWVHTELGYFNGEAVPSNGL
ILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKRVTDVIITHAHADRIGGIKTLKEKGIKAHSTALTAELAKKNGYEEPI
GDLQAITKLKFGNMKIETFYPGKGHTEDNIVVWLSQYNILAGGCLVKSASAKDLGNVADAYVNEWSTSIENVLTRYRNIN
AVVPGHGEVGDRGLLLHTLELLK
>Mature_263_residues
MKERVEKMKNTLLKLGVCVSLLGITPIVSTISSVQAERTVEHKVIKNETGTISISQLNKNVWVHTELGYFNGEAVPSNGL
ILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKRVTDVIITHAHADRIGGIKTLKEKGIKAHSTALTAELAKKNGYEEPI
GDLQAITKLKFGNMKIETFYPGKGHTEDNIVVWLSQYNILAGGCLVKSASAKDLGNVADAYVNEWSTSIENVLTRYRNIN
AVVPGHGEVGDRGLLLHTLELLK

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28903; Mature: 28903

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00743 BETA_LACTAMASE_B_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERVEKMKNTLLKLGVCVSLLGITPIVSTISSVQAERTVEHKVIKNETGTISISQLNKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
VWVHTELGYFNGEAVPSNGLILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKRVTDVII
EEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
THAHADRIGGIKTLKEKGIKAHSTALTAELAKKNGYEEPIGDLQAITKLKFGNMKIETFY
HHCHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEE
PGKGHTEDNIVVWLSQYNILAGGCLVKSASAKDLGNVADAYVNEWSTSIENVLTRYRNIN
CCCCCCCCCEEEEEECCCEEECHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AVVPGHGEVGDRGLLLHTLELLK
EEECCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MKERVEKMKNTLLKLGVCVSLLGITPIVSTISSVQAERTVEHKVIKNETGTISISQLNKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
VWVHTELGYFNGEAVPSNGLILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKRVTDVII
EEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
THAHADRIGGIKTLKEKGIKAHSTALTAELAKKNGYEEPIGDLQAITKLKFGNMKIETFY
HHCHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEE
PGKGHTEDNIVVWLSQYNILAGGCLVKSASAKDLGNVADAYVNEWSTSIENVLTRYRNIN
CCCCCCCCCEEEEEECCCEEECHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AVVPGHGEVGDRGLLLHTLELLK
EEECCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3131315; 2501295; 1904717 [H]