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The map label for this gene is drrB [H]

Identifier: 118478704

GI number: 118478704

Start: 3277376

End: 3278125

Strand: Reverse

Name: drrB [H]

Synonym: BALH_3090

Alternate gene names: 118478704

Gene position: 3278125-3277376 (Counterclockwise)

Preceding gene: 118478705

Following gene: 118478703

Centisome position: 62.36

GC content: 42.0

Gene sequence:

>750_bases
ATGAAAAGCAAAACAGGGGTATTACTTGGGCGCTTAATACGCAATATTATGCGTAGTCCAGATACAATTATTACGGTAGC
GATTACACCGATTATGATGATGCTATTGTTTGTATACGTATTTGGTGGGGCTATACAGACAGGAACAGATAACTACGTCA
ATTATTTATTGCCGGGAATTTTGCTAATGGCTATCGCATCCGGTGTCGCTTACACTTCTGTGCGATTATTTACGGATGTA
AAGAGTGGGCTAATGGCACGTTTTATTACGATGCCAATTAAGCGCTCATCGATATTGTGGGCTCACGTTTTAACCTCTCT
TGTTGCGAATGTTCTTACTATCGTAGTGGTTATTCTTGTTGCGCTCTTAATGGGTTTCCGTTCCAGTGCGAATATTCTAG
ATTGGCTTGGAGTAGCTGGGATACTAGGGATGTTTACGTTAGCACTAACATGGCTAGCTATCATTCCAGGGTTGAAAGCG
AAGTCAATGGAGGGAGCGACAGCGTACTCGTACCCACTAATTTTTCTACCATTTATTAGTTCAGCCTTTGTACCTACCGA
AACGATGCCGAAAATTGTTCGTGTATTTGCTGAAAACCAGCCTGTAACTTCAATCGTGAATGCGATTCGTGCCCTCTTAT
ATGAAGGGACTGTTGGCAACGATATTTGGATTGCACTTGCTTGGTGCGTAGGGATCATGATCATCTCTTACTTTTTCGCT
AGTAAAGCATTTAAACGCCAGATAGGGTAA

Upstream 100 bases:

>100_bases
GAAAGAGATGTTCCCGCCAGCAAAAGTGGAGTATATCGAGAAGCAGCCGACATTGGAAGAAATATTCCTTGCGATCATTG
GCAAAAAGGAGGAGATGTAA

Downstream 100 bases:

>100_bases
GTGAATTAAGTTATCTGAAGTAATATATATGTTTGAAAAAGCACGGAAGATTTTCTGTGCTTTTCTTATTTATTTTCTTC
TTAATGTAACAATTTTCGGT

Product: ABC transporter efflux permease, daunorubicin resistance transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKSKTGVLLGRLIRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIQTGTDNYVNYLLPGILLMAIASGVAYTSVRLFTDV
KSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILVALLMGFRSSANILDWLGVAGILGMFTLALTWLAIIPGLKA
KSMEGATAYSYPLIFLPFISSAFVPTETMPKIVRVFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMIISYFFA
SKAFKRQIG

Sequences:

>Translated_249_residues
MKSKTGVLLGRLIRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIQTGTDNYVNYLLPGILLMAIASGVAYTSVRLFTDV
KSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILVALLMGFRSSANILDWLGVAGILGMFTLALTWLAIIPGLKA
KSMEGATAYSYPLIFLPFISSAFVPTETMPKIVRVFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMIISYFFA
SKAFKRQIG
>Mature_249_residues
MKSKTGVLLGRLIRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIQTGTDNYVNYLLPGILLMAIASGVAYTSVRLFTDV
KSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILVALLMGFRSSANILDWLGVAGILGMFTLALTWLAIIPGLKA
KSMEGATAYSYPLIFLPFISSAFVPTETMPKIVRVFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMIISYFFA
SKAFKRQIG

Specific function: Part of the ABC transporter complex drrAB involved in daunorubicin and doxorubicin resistance. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 27179; Mature: 27179

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKTGVLLGRLIRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIQTGTDNYVNYLLPGI
CCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LLMAIASGVAYTSVRLFTDVKSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLMGFRSSANILDWLGVAGILGMFTLALTWLAIIPGLKAKSMEGATAYSYPLIFLPFIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
SAFVPTETMPKIVRVFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMIISYFFA
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SKAFKRQIG
HHHHHHCCC
>Mature Secondary Structure
MKSKTGVLLGRLIRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIQTGTDNYVNYLLPGI
CCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LLMAIASGVAYTSVRLFTDVKSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLMGFRSSANILDWLGVAGILGMFTLALTWLAIIPGLKAKSMEGATAYSYPLIFLPFIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
SAFVPTETMPKIVRVFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMIISYFFA
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SKAFKRQIG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1924314 [H]