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The map label for this gene is ndhF [H]

Identifier: 118478464

GI number: 118478464

Start: 3003101

End: 3004639

Strand: Reverse

Name: ndhF [H]

Synonym: BALH_2836

Alternate gene names: 118478464

Gene position: 3004639-3003101 (Counterclockwise)

Preceding gene: 118478465

Following gene: 118478463

Centisome position: 57.15

GC content: 36.45

Gene sequence:

>1539_bases
TTGTACATGTTAATTTCGCTGAGTTCATCAACATTGTTAACATTATTTTTTATGGCGCTTAGTGCTTCTTGGCTAAGTGG
ATTGTTGTTTTTACATGCAAGGATGCCTTTACGTTTTGTTCATATCTATATTGGTATCGCTGCTTTGCCTTCATTGGTTT
CTTTACTCGCACTTGTTAATCACAATGGAGATAGAGTTGTAGGGCCTTGGCATTTAGATACTTTAGCTTGGTTCATGGCT
TTCTTTGTTCTTACAATTGGTTTAATCATTCAACGTTTTTCGATACGTTACTTACTGGGAGATCGCTCATATCGAAAATA
CTTTGCACTTTTTACATGTACTACAGGTGTATCTTCAGTCGCATGGTTAAGTAATGATCTTCGTTTCATGATTATTTGTT
GGGGAGCAACTCTTATAGGGTTAGTTTTACTCATAGGGCTAAATAAAGGGTGGAAAGTAGTTAGTGAAGCAACAAAAACT
TCTAGTTATTTATTTACAATAAGCTGGATTGCCTTGCTAGCAGCTATCCTTTGGCTTTTTCAAGTTACTGGACAGTGGCA
GTTAACATCAGTTTTAACGAATGAAAATGTAGCTCAATTTGGAACATTGGAGAAAACAGGAATTAACTTATTGATTATAG
TAGCTGTGATGATTCCAGCAGCACAATGGCCTTTTCAAAGGTGGTTAATTGAGTCTGCTGTCGCTCCAACTCCTGTTTCT
GCTATTATGCATGCGGGTTTAGTAAATGCTGGCGGTATCATGTTAACTAGATTTTCGCCACTTTTTCATGATGATATTGC
ACAAATCATTTTACTTATTTTTTCTAGTATTTCGGTCTTAATCGGAACAGGAATTAGTTTAGTTCAAGTAGATTATAAGC
GTCAGCTAGTAGGCTCCACTATTGCACAAATGGGATTTATGCTTATTCAATGTGCATTAGGCGCTTATTTAGCAGCTGTT
ATTCATTTAATTTTACACGGTTTATTTAAAGCCACACTGTTTTTACAAGCTGGTTCTTCCGTACAACGTGTTGGGGCAGT
GAAGCTGTCTAATGAAAAGATATCTAATTTATGGATTATGATCGGACGTGTTTTCGGATTATTTATAGCGATTGCTTTTT
GGTTTACGACTTCTGGAGAAGGGTATCAATTCGTTAGTGCGTTCATCTTAGGGTGGTCATTATACGTTTCATGGAAACAG
CTTGTTGTTTTTGGAGAGGGAAGAATGGGAAGAATTGTTGGCGTATTTATTTTAGCTGGATTTTCTCTCATTTACTTTAC
TGTTCATAATTCTCTTTATAAATGGTTGCATACTGACATGTATCAAAATGTTCAACCTTCACCTTCAGCCGTTATTTTTG
TTATATGTCTCTTATTATTTGGTAGTGCTATTCGTACTCTCGTTACTCGTAATCAATCCTCGACACTATTTGCTGTAATG
TATCTTTGGTTCGTTCGAGTAGGTGAGGCGAGACAAAAGTCAGTAGAAAGTCATCCAAGCTATCTGAAACATTATGTATC
AAAGGGAGGTAATCAGTGA

Upstream 100 bases:

>100_bases
GAAGTTGTCGGTTTTTTTTATGGGAAAAAACGATGTACTAAAAAGAGTGAAAGAAAATTAAAAGGAATTTTTACAGTTTA
TTTTCGTTTAGAAGGGAGTA

Downstream 100 bases:

>100_bases
TGAGCATACAGTCAATCATAACGAAAGAAACTTTAAAAAAGAAAGATACAAACATTGAAATACAAGAAAAGAATATGAAT
GATTTAGTTGAATCTGCTAG

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MYMLISLSSSTLLTLFFMALSASWLSGLLFLHARMPLRFVHIYIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMA
FFVLTIGLIIQRFSIRYLLGDRSYRKYFALFTCTTGVSSVAWLSNDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKT
SSYLFTISWIALLAAILWLFQVTGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVS
AIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAV
IHLILHGLFKATLFLQAGSSVQRVGAVKLSNEKISNLWIMIGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYVSWKQ
LVVFGEGRMGRIVGVFILAGFSLIYFTVHNSLYKWLHTDMYQNVQPSPSAVIFVICLLLFGSAIRTLVTRNQSSTLFAVM
YLWFVRVGEARQKSVESHPSYLKHYVSKGGNQ

Sequences:

>Translated_512_residues
MYMLISLSSSTLLTLFFMALSASWLSGLLFLHARMPLRFVHIYIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMA
FFVLTIGLIIQRFSIRYLLGDRSYRKYFALFTCTTGVSSVAWLSNDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKT
SSYLFTISWIALLAAILWLFQVTGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVS
AIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAV
IHLILHGLFKATLFLQAGSSVQRVGAVKLSNEKISNLWIMIGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYVSWKQ
LVVFGEGRMGRIVGVFILAGFSLIYFTVHNSLYKWLHTDMYQNVQPSPSAVIFVICLLLFGSAIRTLVTRNQSSTLFAVM
YLWFVRVGEARQKSVESHPSYLKHYVSKGGNQ
>Mature_512_residues
MYMLISLSSSTLLTLFFMALSASWLSGLLFLHARMPLRFVHIYIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMA
FFVLTIGLIIQRFSIRYLLGDRSYRKYFALFTCTTGVSSVAWLSNDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKT
SSYLFTISWIALLAAILWLFQVTGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVS
AIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAV
IHLILHGLFKATLFLQAGSSVQRVGAVKLSNEKISNLWIMIGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYVSWKQ
LVVFGEGRMGRIVGVFILAGFSLIYFTVHNSLYKWLHTDMYQNVQPSPSAVIFVICLLLFGSAIRTLVTRNQSSTLFAVM
YLWFVRVGEARQKSVESHPSYLKHYVSKGGNQ

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=136, Percent_Identity=33.0882352941176, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI1788614, Length=279, Percent_Identity=28.3154121863799, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788831, Length=136, Percent_Identity=32.3529411764706, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788613, Length=240, Percent_Identity=28.75, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56977; Mature: 56977

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMLISLSSSTLLTLFFMALSASWLSGLLFLHARMPLRFVHIYIGIAALPSLVSLLALVN
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
HNGDRVVGPWHLDTLAWFMAFFVLTIGLIIQRFSIRYLLGDRSYRKYFALFTCTTGVSSV
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEEECCCHHHH
AWLSNDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKTSSYLFTISWIALLAAILWLF
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVS
HHCCCEEEEEECCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHH
AIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGST
HHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
IAQMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRVGAVKLSNEKISNLWIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEECCCHHHHHHHH
IGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYVSWKQLVVFGEGRMGRIVGVFILAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
FSLIYFTVHNSLYKWLHTDMYQNVQPSPSAVIFVICLLLFGSAIRTLVTRNQSSTLFAVM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YLWFVRVGEARQKSVESHPSYLKHYVSKGGNQ
HHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MYMLISLSSSTLLTLFFMALSASWLSGLLFLHARMPLRFVHIYIGIAALPSLVSLLALVN
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
HNGDRVVGPWHLDTLAWFMAFFVLTIGLIIQRFSIRYLLGDRSYRKYFALFTCTTGVSSV
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEEECCCHHHH
AWLSNDLRFMIICWGATLIGLVLLIGLNKGWKVVSEATKTSSYLFTISWIALLAAILWLF
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVTGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVS
HHCCCEEEEEECCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHH
AIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGST
HHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
IAQMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRVGAVKLSNEKISNLWIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEECCCHHHHHHHH
IGRVFGLFIAIAFWFTTSGEGYQFVSAFILGWSLYVSWKQLVVFGEGRMGRIVGVFILAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
FSLIYFTVHNSLYKWLHTDMYQNVQPSPSAVIFVICLLLFGSAIRTLVTRNQSSTLFAVM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YLWFVRVGEARQKSVESHPSYLKHYVSKGGNQ
HHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]