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The map label for this gene is glsA2 [H]

Identifier: 118478446

GI number: 118478446

Start: 2981542

End: 2982522

Strand: Reverse

Name: glsA2 [H]

Synonym: BALH_2817

Alternate gene names: 118478446

Gene position: 2982522-2981542 (Counterclockwise)

Preceding gene: 118478447

Following gene: 118478445

Centisome position: 56.73

GC content: 37.0

Gene sequence:

>981_bases
ATGATAGAGGATTCTAGCGTTCAAGTTGAGAGTCAAGAAAAAGTTTGCTTAGATCAATGGGTAGCTCATTATCGAATGTA
TGCAGCTAAGGGACGAAGCGCCAGTTATATTCCAGCTCTGGGGGAAATAAATGTATCGCAGTTAGGTATTTGTATAGTAA
AGCCAGATGGAACAATGATAAAGTCAGGAGATTGGGAGGTACCTTTCACATTACAAAGTATATCAAAAGTAATCGGTTTT
ATAGCCGCTTGTTTAAGTCGCGGTATTTCTTATGTATTAGAACGAGTTGACGTAGAGCCAACTGGAGATGCCTTCAATTC
GATTATTCGTTTAGAGATACATAAACCAGGAAAACCTTTTAATCCTATGATTAATGCTGGAGCGATTACGATATCTTCAC
TTTTGCCAGGGACATCGGTGCAAGAAAAATTAGAATCTATATACGTATTAATTGAGAAAATGATAGAGAAGCGTCCTGCT
ATTAATGAAATAGTATTTCAATCAGAATGGGAAACGGCTCATCGTAATAGAGCTTTAGCATACTATTTAAAGGAGAATGG
TTTTCTAGAATCAGATGTGGAGGAGACACTAGAGGTTTACCTAAAACAATGTTCGATTGAAATAAATACAGAAGATATTG
CCTTAATAGGACTTATACTAGCACATGATGGATATCATCCTATTCGCAAAGAACAAGTGCTCCCTAAAGAAGTAGCTAGG
TTAACAAAAGCTTTAATGCTTACTTGTGGAATGTACAATGCTTCTGGCAAATTTGCCGCTTTCATTGGGTTACCAGCTAA
AAGTGGGGTATCCGGCGGAATTATGACACTTGTTCCCTCAAAATCTAGGAAGGATTTATCGTTCCAAGATGGATGTGGTA
TTGGTATTTACGGACCAGCCATTGATGAATATGGGAATAGTTTACCAGGAAGTATGTTGTTAGAACATATTGCAAAAGAA
TGGGATTTAAGTATATTTTAA

Upstream 100 bases:

>100_bases
ATGTCTGAATATTTTTCTTGGTTCTAGTGCAAATAGTATCGATGATATTCAAGAAAAAATTATTTTATATCAAGTTAATA
GTACGGGGGAATATTGTTAA

Downstream 100 bases:

>100_bases
AAAGGAGCACAGATATTTTGATGTTAGAGCGAGTCCAAAAGTGTTCAGACCTTATATGGTGTCTGAACATTTTTGAGTTA
TAAAGTATCTTTCTAAAGTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIEDSSVQVESQEKVCLDQWVAHYRMYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITISSLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGSMLLEHIAKE
WDLSIF

Sequences:

>Translated_326_residues
MIEDSSVQVESQEKVCLDQWVAHYRMYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITISSLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGSMLLEHIAKE
WDLSIF
>Mature_326_residues
MIEDSSVQVESQEKVCLDQWVAHYRMYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITISSLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGSMLLEHIAKE
WDLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=284, Percent_Identity=38.7323943661972, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20336214, Length=297, Percent_Identity=35.016835016835, Blast_Score=171, Evalue=9e-43,
Organism=Escherichia coli, GI1786693, Length=296, Percent_Identity=35.8108108108108, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787804, Length=316, Percent_Identity=33.2278481012658, Blast_Score=180, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=33.2225913621262, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17532727, Length=299, Percent_Identity=32.7759197324415, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI193204073, Length=308, Percent_Identity=32.4675324675325, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=310, Percent_Identity=32.9032258064516, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281363241, Length=301, Percent_Identity=35.2159468438538, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116008307, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653158, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281363239, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653162, Length=301, Percent_Identity=35.2159468438538, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653164, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653156, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653166, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 35923; Mature: 35923

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDSSVQVESQEKVCLDQWVAHYRMYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KSGDWEVPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITISSLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
IDEYGNSLPGSMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIEDSSVQVESQEKVCLDQWVAHYRMYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KSGDWEVPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITISSLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
IDEYGNSLPGSMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]