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The map label for this gene is kipR [H]

Identifier: 118478398

GI number: 118478398

Start: 2925053

End: 2925859

Strand: Reverse

Name: kipR [H]

Synonym: BALH_2763

Alternate gene names: 118478398

Gene position: 2925859-2925053 (Counterclockwise)

Preceding gene: 118478399

Following gene: 118478397

Centisome position: 55.66

GC content: 38.17

Gene sequence:

>807_bases
TTGTTTCGAAAAATGGAATCTAAGTTCCGAAATTCGGAACAAGAGGGAGATAGAATGAGTATAAATAAAACGGCAGTTAA
GACAATGGATATTTTAGAGTTGTTTTATGAGCATGAAGAACTCAGTTTAACAGAGATGGTTCAGCTTACAAGTATGCCGA
AAACATCTGTTTATCGTTTAATTGGCTCGTTAGAAGAAATGGAGTTTTTACAAAAAAACGAAAAGGGGAAATATCGTCTA
GGAGTCGTTTTTTTACGGTTTGGTCAACTTGTTTCGCAAAGATTATCAGTAAGAAATATTGCGATTCCATATATGAAAGA
GCTTAGAGATAATTTAGGGCAGGCAGTTAATTTAATTATTCAAGATGGTAACGACGCGATTTATGTGGAAAAAATGGAAG
GCGTTCAGCCTGTACGCGTGTATACGGCGGTTGGAAGAAGAGCACCACTTTATGCTGGTGCATGTCCGAGAATTTTACTA
TCGTATTTTACCGAGGAAGAGAAACAGAAGTACGTAGAGGAAACGGATTTCAAACAGTTTGCAGATGGAACAATCGTAGA
TAAGAAACAATTGCTAGAAGTGTTACAAATGGCGAAAAAGGAAGGACATACAATTAGCTACTCGGAGTTAGAAAATCATA
CAGCAGCTATAGCAGCGCCCATTTTTGCAAGCGACGGAACGGTTGTAGCAGGCATTAGTATTTCAGGATTAGCAATTGAG
TACAGCGAAAGTAACATTCCATATTTTATCGCTAAGGTGAAAGAGACAGCGAATCGCATTTCGAAAGAACTCGGCTTTTT
GGCATAG

Upstream 100 bases:

>100_bases
TAAGAGCGTTATAAAGAAAAAGTATGGGAGAATATATATTCTTCCATACTTTTTTTGTTGATAGAATTAAAAGAATATTT
TATAATTTTAAATTATATGT

Downstream 100 bases:

>100_bases
AAAGAGGGAGTAGGATGAAATTTTCTGCGTTAGGGGATCAAGCAATTATTGTTACATTTGGTGAGGAAATCGGGATGGAT
GTATATGAAAAAGTACAACG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFRKMESKFRNSEQEGDRMSINKTAVKTMDILELFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRL
GVVFLRFGQLVSQRLSVRNIAIPYMKELRDNLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILL
SYFTEEEKQKYVEETDFKQFADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIE
YSESNIPYFIAKVKETANRISKELGFLA

Sequences:

>Translated_268_residues
MFRKMESKFRNSEQEGDRMSINKTAVKTMDILELFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRL
GVVFLRFGQLVSQRLSVRNIAIPYMKELRDNLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILL
SYFTEEEKQKYVEETDFKQFADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIE
YSESNIPYFIAKVKETANRISKELGFLA
>Mature_268_residues
MFRKMESKFRNSEQEGDRMSINKTAVKTMDILELFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRL
GVVFLRFGQLVSQRLSVRNIAIPYMKELRDNLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILL
SYFTEEEKQKYVEETDFKQFADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIE
YSESNIPYFIAKVKETANRISKELGFLA

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=27.3809523809524, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788131, Length=244, Percent_Identity=28.2786885245902, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786715, Length=221, Percent_Identity=31.2217194570136, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788581, Length=241, Percent_Identity=24.4813278008299, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789999, Length=260, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=27.4336283185841, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=23.4817813765182, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30407; Mature: 30407

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKMESKFRNSEQEGDRMSINKTAVKTMDILELFYEHEELSLTEMVQLTSMPKTSVYRL
CCCHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
IGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSQRLSVRNIAIPYMKELRDNLGQAVNLII
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEE
QDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFTEEEKQKYVEETDFKQF
ECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIE
CCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHCCHHHHEEEEEECCCCEEEEEEEECEEEE
YSESNIPYFIAKVKETANRISKELGFLA
ECCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFRKMESKFRNSEQEGDRMSINKTAVKTMDILELFYEHEELSLTEMVQLTSMPKTSVYRL
CCCHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
IGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSQRLSVRNIAIPYMKELRDNLGQAVNLII
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEE
QDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFTEEEKQKYVEETDFKQF
ECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIE
CCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHCCHHHHEEEEEECCCCEEEEEEEECEEEE
YSESNIPYFIAKVKETANRISKELGFLA
ECCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]