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The map label for this gene is argD [H]

Identifier: 118478345

GI number: 118478345

Start: 2874764

End: 2875981

Strand: Reverse

Name: argD [H]

Synonym: BALH_2709

Alternate gene names: 118478345

Gene position: 2875981-2874764 (Counterclockwise)

Preceding gene: 118478347

Following gene: 118478344

Centisome position: 54.71

GC content: 33.33

Gene sequence:

>1218_bases
ATGTCGGATTGGTTTCAATTAGATAAAGAATATATGATGTCTACATATTGTCGTACAGAGGTTGCAATGGAAAGAGGGGA
AGGGTGCAAGCTTTATGATGTGGATGGTAAAGAGTATTTAGATTTATTTTCTGGCGTAGGAGTAAATGTATTAGGATATA
ATCATCCTAAAATTGTACAAACCACAATGGATCAAGTTACGAAATCGTTGCATCTACCGTTTCATTTTTTAAATCCAGTT
GCGATTGAGTATGCAAAGAAATTAGTTGATTGCTCATTAAAAAACGGAAAAGTCTTTTTTACAAACTCAGGTACGGAAGC
GACAGAAACGACATTAAAATTAATTGATAAATATAGAGCTATTACAAATGAAGAACGTGAAGGAATTGTAGTGCTGAAGA
ATAGTTTCCACGGGCGTACGCTAGGAGCACTTCATTTTACGAGACAAGAAAGTGTATATCAAAATTTCCCTACGACATCT
ATTCCTGTATATGAAGTTGAGCGTGAGAATATAGAGCAATTAGAAGAAACAATTATAAATGAAAATCCCATAGCGATTCT
GTTAGAACCTGTATTAGGAAGTGGAGGTATTTATCCTTTATCGCGTGAATATTTACATGGTGTTCAAAACTTATGTGATA
AATATAATGTCATTCTTATCGTTGATGAAGTGCAAAGTGGTATGGGGAGAACAGGAAAACTTTTTGCTTATCAAAATTTC
AATATTACACCACATATTATTCAAATTGGTAAAGGAGCAGGAGGTGGGATACCGCTAGGTGGAATTATTGTAGGTGAAAA
GTTATGTGATGTATTTGCGCCAGGAGATCACGGGACAACATTTGCTCATTCATCAATGGGAACAGCTTTAGGTTTAACTG
TATTAAATACATTACTTGATGATGGGTTAATGCAAGAAGCGTATGAAATGTCACTTTATTTAAATGATAAATTGCAAGAA
ATTCAGAAAGAAAATTCTTATTATATTGAGGAAGTACGTCATGCTGGCATGATGTTTGGAATTAGTTTGAATGATACAAA
TGAAAATGTGAAGAAATTACAGGTAGAGCTAATGGAGAAAGGAATTTTAGTTGACGTAACACAAGGGAATATCATCCGTT
TACTTCCTCCATATATAATTACAAAAGAAGAAATTGATACATTTATTACTCAATTTATTTTTTGTATAGATAAAGTTGCT
GCTGTAGTAAGTGCTTAA

Upstream 100 bases:

>100_bases
AACATTACTATTAAAATTTCAATCTTAAAAATGAATTTATACATGACTTTATAGAGAATGAACATAAATAAACAGGGAAA
ATAACTAGGAGGAATGTAAC

Downstream 100 bases:

>100_bases
AAGTTAAAAGTTATATTTTATATAAAGTGCACTCTAATTGTTAGAAATAGTTTTACAATTAGGGTGCATTTTTTATAGTA
GAATTTTGTGAAATACAGTC

Product: aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSDWFQLDKEYMMSTYCRTEVAMERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPV
AIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAITNEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPTTS
IPVYEVERENIEQLEETIINENPIAILLEPVLGSGGIYPLSREYLHGVQNLCDKYNVILIVDEVQSGMGRTGKLFAYQNF
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYEMSLYLNDKLQE
IQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCIDKVA
AVVSA

Sequences:

>Translated_405_residues
MSDWFQLDKEYMMSTYCRTEVAMERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPV
AIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAITNEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPTTS
IPVYEVERENIEQLEETIINENPIAILLEPVLGSGGIYPLSREYLHGVQNLCDKYNVILIVDEVQSGMGRTGKLFAYQNF
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYEMSLYLNDKLQE
IQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCIDKVA
AVVSA
>Mature_404_residues
SDWFQLDKEYMMSTYCRTEVAMERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPVA
IEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAITNEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPTTSI
PVYEVERENIEQLEETIINENPIAILLEPVLGSGGIYPLSREYLHGVQNLCDKYNVILIVDEVQSGMGRTGKLFAYQNFN
ITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYEMSLYLNDKLQEI
QKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEKGILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCIDKVAA
VVSA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=29.5629820051414, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=28.9655172413793, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=24.8306997742664, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=24.9394673123487, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=24.8062015503876, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226442705, Length=413, Percent_Identity=24.455205811138, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=22.4824355971897, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=22.4824355971897, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=22.4824355971897, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1788044, Length=385, Percent_Identity=32.7272727272727, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=27.5510204081633, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI145693181, Length=376, Percent_Identity=32.9787234042553, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=30.8252427184466, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=30.126582278481, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786991, Length=383, Percent_Identity=26.6318537859008, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786349, Length=364, Percent_Identity=27.7472527472527, Blast_Score=121, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=31.0880829015544, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=265, Percent_Identity=31.3207547169811, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=25.8503401360544, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=401, Percent_Identity=23.6907730673317, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=22.4256292906178, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=182, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=32.5980392156863, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=28.9537712895377, Blast_Score=185, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=465, Percent_Identity=24.5161290322581, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=440, Percent_Identity=23.4090909090909, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=31.7135549872123, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28574759, Length=428, Percent_Identity=25.7009345794392, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI161085790, Length=410, Percent_Identity=25.609756097561, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=23.8663484486874, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281366494, Length=379, Percent_Identity=25.5936675461741, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667139, Length=379, Percent_Identity=25.5936675461741, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667143, Length=379, Percent_Identity=25.5936675461741, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45325; Mature: 45193

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWFQLDKEYMMSTYCRTEVAMERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
TTMDQVTKSLHLPFHFLNPVAIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ITNEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPTTSIPVYEVERENIEQLEETIIN
HCCCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCC
ENPIAILLEPVLGSGGIYPLSREYLHGVQNLCDKYNVILIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEEEEEECC
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCEEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHH
DGLMQEAYEMSLYLNDKLQEIQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHC
GILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCIDKVAAVVSA
CCEEEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDWFQLDKEYMMSTYCRTEVAMERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
TTMDQVTKSLHLPFHFLNPVAIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ITNEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPTTSIPVYEVERENIEQLEETIIN
HCCCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCC
ENPIAILLEPVLGSGGIYPLSREYLHGVQNLCDKYNVILIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEEEEEECC
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCEEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHH
DGLMQEAYEMSLYLNDKLQEIQKENSYYIEEVRHAGMMFGISLNDTNENVKKLQVELMEK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHC
GILVDVTQGNIIRLLPPYIITKEEIDTFITQFIFCIDKVAAVVSA
CCEEEECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]