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The map label for this gene is rpiA [H]

Identifier: 118478151

GI number: 118478151

Start: 2669800

End: 2670510

Strand: Direct

Name: rpiA [H]

Synonym: BALH_2508

Alternate gene names: 118478151

Gene position: 2669800-2670510 (Clockwise)

Preceding gene: 118478150

Following gene: 118478152

Centisome position: 50.78

GC content: 37.27

Gene sequence:

>711_bases
TTGAAAATTCAGGCCTTGATGCTGGACCACGTCCGGCGGAGTAAAGCGATGGATTTAAAACAGATAGCTGGTGAATATGC
TGCAACCTTCGTAAAAGATGGTATGAAGATTGGTCTTGGCACAGGATCAACTGCATACTGGACGATACAAAAATTAGGTC
AGCGTGTAAAAGAGGGATTATCAATTCAAGCTGTCCCGACATCAAAGGAAACGGAAGCATTGGCACAGCAGCTAAATATT
CCGTTGATTTCGTTAAACGACGTACAAAGTCTTGATCTTACAATTGATGGAGCTGATGAAATTGATTCTAATTTACAGCT
TATTAAAGGAGGCGGTGGTGCATTACTTCGCGAGAAAATTGTAGCCTCCTCCTCGAAAGAACTTATCATTATCGTTGATG
AATCAAAAGTTGTGACACGTTTAGGGACTTTTCCGTTACCTATTGAAATCATACCTTTTGCATGGAAACAAACCGAAAGT
AAAATTCAATCTTTAGGATGTCAAACAACGTTACGCTTAAAAAATAATGAAACGTTTATCACCGATAATAATAACATGAT
TATCGATTGTATATTCCCTAATCATATACCTACTCCTTCCGATTTACACAAACGATTAAAAATGATTACTGGTGTAGTTG
AAACCGGATTGTTTGTTAATATGACTAGTAAGGCGATTATTGGAACAAAAAACGGGATACAGGAATTATAA

Upstream 100 bases:

>100_bases
GAAAAAAATGCGATGACAGAAAAAGGAATTGAAGATCATTTACGATTATCTTGTCAAATGCGTGTACATAAGGATATAGT
CGTTCGTCCGGTACTTACAG

Downstream 100 bases:

>100_bases
TGAATGCTGACTCTTACAGTCAGCTTTTTTATATTTTCTCGTTATTACGTAACATTATGATATACTATGAAAACAAAAGT
ACATCACACTAGAAAGGATT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKIQALMLDHVRRSKAMDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNI
PLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTES
KIQSLGCQTTLRLKNNETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL

Sequences:

>Translated_236_residues
MKIQALMLDHVRRSKAMDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNI
PLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTES
KIQSLGCQTTLRLKNNETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
>Mature_236_residues
MKIQALMLDHVRRSKAMDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNI
PLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTES
KIQSLGCQTTLRLKNNETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=38.7665198237885, Blast_Score=144, Evalue=7e-35,
Organism=Escherichia coli, GI1789280, Length=220, Percent_Identity=39.5454545454545, Blast_Score=141, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17551758, Length=222, Percent_Identity=32.8828828828829, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6324669, Length=215, Percent_Identity=34.8837209302326, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=38.3495145631068, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25859; Mature: 25859

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQALMLDHVRRSKAMDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCC
SIQAVPTSKETEALAQQLNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKI
EEEEECCCHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHH
VASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNNETFI
HHCCCCCEEEEECCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEEECCEEEE
TDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
ECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MKIQALMLDHVRRSKAMDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCC
SIQAVPTSKETEALAQQLNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKI
EEEEECCCHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHH
VASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNNETFI
HHCCCCCEEEEECCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEEECCEEEE
TDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
ECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]