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The map label for this gene is gntR [H]

Identifier: 118478054

GI number: 118478054

Start: 2579630

End: 2581084

Strand: Reverse

Name: gntR [H]

Synonym: BALH_2406

Alternate gene names: 118478054

Gene position: 2581084-2579630 (Counterclockwise)

Preceding gene: 118478065

Following gene: 118478052

Centisome position: 49.1

GC content: 34.3

Gene sequence:

>1455_bases
GTGAACGAAGGAGTTTTTTTGATGACAACTAGTAAAAAAACGCCTAAGTATCGGCAAATAGTAGACTATATGAAAGAAAA
AATTGAAAATGGAGAATGGCCAATTGGAAGTAAGACCCCTAGTCAAAGGCAGTTAGCGAAATTATTTCAAGTAAATCGTA
GCACTGTAATAACTGCACTAGATGAACTTATGGCTGATGGATTGATTCAAGGGAAAATTGGAGCAGGAACAATTGTAACG
AATAATACATGGTCATTATTAGCGACGAATCCCCCGCCCGATTGGAGTGAATATGTAAAAGCCGGTATTCATAAACCAAG
CAAGTTAATGGTACGAGAAATAAATAAAGCAGAATCAAATAACAAACTTATCCATCTTAGTAAAGGCGAACTTGCTCCTA
ATCTTTTTCCATTAGAAACGATGCAGTCCATTATGAAAAAAGTAAGTGAGGAATTAGATTATTTTGGATATGAGGAACAA
AAAGGGTTTTATCCGTTACGTGAAGCAATAAGTAAATACGTAAAATCATTTGGAATACATGCATCACCGAGTTCCATATT
AATCGTCTCGGGTGCATTACAAGCATTGCAATTAATATCAATTGGTCTTTTACATAGAGAGTCTACCGTTTTACTTGAAC
AACCTTCTTACTTATATTCACTTCATGTATTTCAATCAGCAAATATTAATCTATCTGGTATATCTATGGATCCTCACGGT
ATATTACCTAACGAGTTATTAAAACGAATTAAATACAGTCAGAAGAAAAACATTTTATATTCAATTCCTTGTTTTCAAAA
TCCAACAGGCATATTAATGTCTAAAGAGCGGAAAAAAGAAATATTAAAAATATGTGAAAAGGAACAGTTACCTATTATTG
AAGATGATATTTACCGCGAGTTATGGATTGATGCACCGCCCCCAGCTCCTTTAAAATCAAGAGATAAACATGGACATATA
TTATATATCGGTAGTCTCTCTAAGACGCTTACCCCAGGACTTAGAATTGGATGGGTTATCGGTCCAGAACCAGTTATTGA
TAGATTATCAGATATAAAAATGCAAACAGATTATGGATCAAGCTCCTTATCCCAAAGAGTTGCTGCTGAATGGATAAATA
AAGGATTTTATGAGGAACATGTAGCGAACGTAAGAATTAAACTAAAAGAACGAAGACAAATAATGATACGAGCTTTACAT
AAGTATTGTGCAGATATTGCCACCTGGGATATACCTAGTGGTGGATTTTTTATATGGCTAAAGGTAATACCTAGCATTCC
GATGAAGAAATTATTTTCAGAGGCACTATCAAAAGGAGTTCTTTTAAATCCAGGACGTATATATGAAGAAGAATCAGACC
GGTATATTCGTTTATCATATGGATATGCTTCTTCAGAGCAAATGACTAACGGGATTAAATTGTTGAGTGAATTAATTCGT
AAGCTAACGGCATAA

Upstream 100 bases:

>100_bases
TTTATAATTACCAATTATTTCTTTTCATCATATTTAATAGTTGATACAATGTCTTCAACCAGTTTTTTATCGTAAAAACC
AACCACTTGGCATTTTTTGA

Downstream 100 bases:

>100_bases
CAAAAACTCCTCTTTTTCTATAGAGGAGTTTTTATGTATCTTATTTACCACAATCTCATTTCCTGACCTAATAAAATAAG
TGCTTCATAAGGATCCCCGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNEGVFLMTTSKKTPKYRQIVDYMKEKIENGEWPIGSKTPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVT
NNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINKAESNNKLIHLSKGELAPNLFPLETMQSIMKKVSEELDYFGYEEQ
KGFYPLREAISKYVKSFGIHASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHG
ILPNELLKRIKYSQKKNILYSIPCFQNPTGILMSKERKKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHI
LYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALH
KYCADIATWDIPSGGFFIWLKVIPSIPMKKLFSEALSKGVLLNPGRIYEEESDRYIRLSYGYASSEQMTNGIKLLSELIR
KLTA

Sequences:

>Translated_484_residues
MNEGVFLMTTSKKTPKYRQIVDYMKEKIENGEWPIGSKTPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVT
NNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINKAESNNKLIHLSKGELAPNLFPLETMQSIMKKVSEELDYFGYEEQ
KGFYPLREAISKYVKSFGIHASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHG
ILPNELLKRIKYSQKKNILYSIPCFQNPTGILMSKERKKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHI
LYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALH
KYCADIATWDIPSGGFFIWLKVIPSIPMKKLFSEALSKGVLLNPGRIYEEESDRYIRLSYGYASSEQMTNGIKLLSELIR
KLTA
>Mature_484_residues
MNEGVFLMTTSKKTPKYRQIVDYMKEKIENGEWPIGSKTPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVT
NNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINKAESNNKLIHLSKGELAPNLFPLETMQSIMKKVSEELDYFGYEEQ
KGFYPLREAISKYVKSFGIHASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHG
ILPNELLKRIKYSQKKNILYSIPCFQNPTGILMSKERKKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHI
LYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALH
KYCADIATWDIPSGGFFIWLKVIPSIPMKKLFSEALSKGVLLNPGRIYEEESDRYIRLSYGYASSEQMTNGIKLLSELIR
KLTA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=394, Percent_Identity=29.6954314720812, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI33469970, Length=394, Percent_Identity=29.6954314720812, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4507369, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787710, Length=471, Percent_Identity=24.416135881104, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790797, Length=481, Percent_Identity=26.4033264033264, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1788722, Length=329, Percent_Identity=24.3161094224924, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321236, Length=361, Percent_Identity=24.3767313019391, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6321000, Length=271, Percent_Identity=26.5682656826568, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356535, Length=355, Percent_Identity=23.6619718309859, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18859735, Length=209, Percent_Identity=25.8373205741627, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54851; Mature: 54851

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEGVFLMTTSKKTPKYRQIVDYMKEKIENGEWPIGSKTPSQRQLAKLFQVNRSTVITAL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
DELMADGLIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINKAESN
HHHHHCCCEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC
NKLIHLSKGELAPNLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIH
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCC
ASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHG
CCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECCEEEEEECCCCCC
ILPNELLKRIKYSQKKNILYSIPCFQNPTGILMSKERKKEILKICEKEQLPIIEDDIYRE
CCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHH
LWIDAPPPAPLKSRDKHGHILYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGS
HCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCC
SSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIATWDIPSGGFFIWL
HHHHHHHHHHHHHCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
KVIPSIPMKKLFSEALSKGVLLNPGRIYEEESDRYIRLSYGYASSEQMTNGIKLLSELIR
EHHCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
KLTA
HHCC
>Mature Secondary Structure
MNEGVFLMTTSKKTPKYRQIVDYMKEKIENGEWPIGSKTPSQRQLAKLFQVNRSTVITAL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHH
DELMADGLIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINKAESN
HHHHHCCCEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCC
NKLIHLSKGELAPNLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIH
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCC
ASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHG
CCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECCEEEEEECCCCCC
ILPNELLKRIKYSQKKNILYSIPCFQNPTGILMSKERKKEILKICEKEQLPIIEDDIYRE
CCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHH
LWIDAPPPAPLKSRDKHGHILYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGS
HCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCC
SSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIATWDIPSGGFFIWL
HHHHHHHHHHHHHCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
KVIPSIPMKKLFSEALSKGVLLNPGRIYEEESDRYIRLSYGYASSEQMTNGIKLLSELIR
EHHCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
KLTA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]