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The map label for this gene is yxdK [H]

Identifier: 118477990

GI number: 118477990

Start: 2507055

End: 2508059

Strand: Direct

Name: yxdK [H]

Synonym: BALH_2337

Alternate gene names: 118477990

Gene position: 2507055-2508059 (Clockwise)

Preceding gene: 118477989

Following gene: 118477992

Centisome position: 47.69

GC content: 32.74

Gene sequence:

>1005_bases
TTGGGATACGGGTATGGAAAAATGATAAGGCTGTTTATACGTGATCATATACCACTTATTTGTTTTACAGCAATTCAACT
ACTATCCATATTTCTCGTATATTGGTTTGATGGGTATAACCATACTGCAACGGCATTATACGCAATGTTTTTAGGTGCCT
TTTTTATGGTAGGTTATTTAATATTTCGTTACTTTACACATCGTTCTTTTTATGAGCGTTTAGCAAACCCGATGCAATCT
TTAGATGAATCTGTTCAAAATTCTGATTTTGCAGCTATATCTGCTGCTCTTCAACACTTGCTTGAGGTACAATATCGCCA
TTATCAAAATCAGCTTCAAATACAAGAGAGAAAAAATAATGATCATTTAACTTTTATGAATCAGTGGATTCATCAAATGA
AAACACCTTTATCTGTCATAGAATTAATTACACAAGATGAAGTTGATCCACGCTTCGAAAGTATAAATGAGGAAACAGAT
GGACTGAAAAAGGGGTTAGAGATGGCATTGTATGTTGCACGTTTAGAAGCATTTACACAAGATTTTTATGTAGAAAAAGT
ACAGCTATATAAAATAGTGAATGATTCTGTGCATGAACATAAACGTTTCTTTATCCGGAATTTTGTATATCCAGAGCTTA
AAGTTGAGAAAGATATTACTGTAGAAAGTGATGCGAAATGGTTACAATTTTTAATTGGACAAATACTATCGAATGCGATT
AAATATTCATCTGGTAGTAGAGAGAAGATTAAAGTGAAAGCTTGTAAGGAAGGTAATACAGTCATACTTGAAATTGCTGA
TAACGGTGTAGGCATACCGAAGCAAGATTTACCAAGAGTATTTAAACCTTTCTTTACAGGAGAAAATGGCAGAGATTTTA
AAGAATCAACTGGAATGGGGCTATATCTTGTATATGAAATTACGAAACAATTAGGACATAGTGTAGAAATCCATTCAGAA
GTTGGTAAAGGTACCGTTGTACGTATTAAATTTTTTAATGTGTAA

Upstream 100 bases:

>100_bases
TAAGTGTAAATACGACACGTGTGCGAAAGAAGTTAAAAACGTTACAGATTGAGGATGCGATTGAAACAATTCGTAGTGTT
GGATATAGATTGCATATTAC

Downstream 100 bases:

>100_bases
AAATATGTAATCTAGGCTAAAGAACTTTGGAGATAAGTTTTTTAGCCTTTTTGTATAGCGGTTATATGAAATGGCAAAAC
GTTATATTAGCATGTATAAT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MGYGYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQS
LDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETD
GLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSE
VGKGTVVRIKFFNV

Sequences:

>Translated_334_residues
MGYGYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQS
LDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETD
GLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSE
VGKGTVVRIKFFNV
>Mature_333_residues
GYGYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQSL
DESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDG
LKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIK
YSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEV
GKGTVVRIKFFNV

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=283, Percent_Identity=24.3816254416961, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38884; Mature: 38753

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYGYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYL
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IFRYFTHRSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDGLKKGLEMALYVARLEAFTQ
CCCHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMG
HCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCC
LYLVYEITKQLGHSVEIHSEVGKGTVVRIKFFNV
CHHHHHHHHHHCCCEEEHHHCCCCEEEEEEEECC
>Mature Secondary Structure 
GYGYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IFRYFTHRSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDGLKKGLEMALYVARLEAFTQ
CCCHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMG
HCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCC
LYLVYEITKQLGHSVEIHSEVGKGTVVRIKFFNV
CHHHHHHHHHHCCCEEEHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]