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The map label for this gene is gntR [H]

Identifier: 118477979

GI number: 118477979

Start: 2496728

End: 2498098

Strand: Direct

Name: gntR [H]

Synonym: BALH_2326

Alternate gene names: 118477979

Gene position: 2496728-2498098 (Clockwise)

Preceding gene: 118477978

Following gene: 118477980

Centisome position: 47.49

GC content: 30.56

Gene sequence:

>1371_bases
ATGTATAAGTATTTACATATTTTAAACGATATAGAAAAAATGATTCAAAATGGAGCGATAAATGAAGGACAGAAATTACC
ATCAATACGGTCACTTGTTACGCAATATGAATGTAATAAGGCGACAGTTATACGTGCGCTTTATGAATTGGAAAAGCGTC
ATATTATATATTCTGTCCCTCAAAGTGGATACTACGTTGTTAAAAAATCAGGGAGTACTATAGAAAATGACGAGATAATT
GATTTCGCTTCTTCAGCACCAGATCCAGATGTTTTCCCATATTTAGATTTTCAGCATTGCATTAATAAGGCTATTGATAC
TTATAAAAATGATTTGTTCGTATATGGAACGCCAAAAGGATTACCATCTTTAATTCCAGTCATTCAAAAACAGTTGGCAA
ATTATCAAGTGTTCACGAAAGAAGACAATATTTTTATAACGTCAGGAGTGCAGCAGGCACTTGCAATATTAACTTCTATA
CCATTTCCAAATAAAAATGAAACAATATTAGTTGAACAACCAACGTATCATTTATATATAGAATATCTAGAAATAAATAA
AATTCCAGTAATCGGTATTAAACGTACGAGTGAAGGTATTGATTTAAATGAATTGGAGCGTATTTTTCGAACGGGTAAAA
TAAAATTCTTTTATACAATACCAAGATGTCATCATCCACTTGGAACTTCTTATTCTAAAGGTGAGAAAGAAAAAGTCGTA
CTATTGGCTAAGAAATATAATGTATTTATAGTGGAAGATGATTATTTAGCAGATTTAGAAACAGATTCAAAAGCCGATCC
GTTATATAGCTTGAATCATGGTAATCATGTCATATATTTGAAAAGTTATTCGAAAATTATTTTTCCTGGTTTACGAGTTG
GTGTAGCAGTTATTCCACCGGTTATTTCGAGCGCTTTCCATACATATAAAAAGGTTTTAGATATTGATAGCCCGATGATA
TCCCAAGCTGCTTTAGAAATTTATATAAAGAGTGACATGTTCGAGCGCCATAAAAATAAAATTAAATCTTCCTATAATAA
TAGATCTAAAAAACTAGCTGAAGCATTAGAAAGAATTCATAGTGAAAACCCGCTTTTATTCACATATAAAAAGCAAAATA
CAATTGGAATCCATACTTGTTTAGAAGTACATAAAACCAGTATTTCGGACATGTTGATACAAAGACTAAGTGAAATGCAA
ATCAGTATTGATACGATTGATAAGAATTATGTAAGAGGTTTTCCGAAACAAAGACTATTAAAGTTGAACGTATCAAATGT
AAAGGAAGATAGGATTGAGAAAGGAATTCGTATAGTAATGGAAGAAATCAAACAAGCTGAACGTCTAAATTTTCAATTTA
AAAAAGAATAA

Upstream 100 bases:

>100_bases
TACGATATAGAAGATCGGAAAATTAACTAATTGAGGAATGGATGGTATATAAATAAAAAGTCAGTGTAATTAAATATAGA
ATTGCTGAAGGAGGTGTAAT

Downstream 100 bases:

>100_bases
AATGGGAAAGGAGGTTTGTTGTGAGACGCAAAATAATTCTCTTGTTTGTGTGTATCGCTATTATAATTGGAGCTGTCGTT
CTAATTAATTATTATAAAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDEII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKIPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRCHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLNHGNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSDMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLEVHKTSISDMLIQRLSEMQ
ISIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEKGIRIVMEEIKQAERLNFQFKKE

Sequences:

>Translated_456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDEII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKIPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRCHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLNHGNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSDMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLEVHKTSISDMLIQRLSEMQ
ISIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEKGIRIVMEEIKQAERLNFQFKKE
>Mature_456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDEII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKIPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRCHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLNHGNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSDMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLEVHKTSISDMLIQRLSEMQ
ISIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEKGIRIVMEEIKQAERLNFQFKKE

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=22.6044226044226, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=22.6044226044226, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1787710, Length=394, Percent_Identity=25.6345177664975, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1790797, Length=377, Percent_Identity=23.8726790450928, Blast_Score=111, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6321236, Length=211, Percent_Identity=26.0663507109005, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356535, Length=319, Percent_Identity=24.7648902821317, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52555; Mature: 52555

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECC
QSGYYVVKKSGSTIENDEIIDFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKG
CCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
LPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSIPFPNKNETILVEQPTYHLYI
CHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
EYLEINKIPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRCHHPLGTSYSKGEKEKVV
EEEEECCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LLAKKYNVFIVEDDYLADLETDSKADPLYSLNHGNHVIYLKSYSKIIFPGLRVGVAVIPP
EEEEECEEEEEECCCEECCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHHHHHHHH
VISSAFHTYKKVLDIDSPMISQAALEIYIKSDMFERHKNKIKSSYNNRSKKLAEALERIH
HHHHHHHHHHHHHCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SENPLLFTYKKQNTIGIHTCLEVHKTSISDMLIQRLSEMQISIDTIDKNYVRGFPKQRLL
CCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCHHHEE
KLNVSNVKEDRIEKGIRIVMEEIKQAERLNFQFKKE
EEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECC
QSGYYVVKKSGSTIENDEIIDFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKG
CCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
LPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSIPFPNKNETILVEQPTYHLYI
CHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
EYLEINKIPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRCHHPLGTSYSKGEKEKVV
EEEEECCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LLAKKYNVFIVEDDYLADLETDSKADPLYSLNHGNHVIYLKSYSKIIFPGLRVGVAVIPP
EEEEECEEEEEECCCEECCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHHHHHHHH
VISSAFHTYKKVLDIDSPMISQAALEIYIKSDMFERHKNKIKSSYNNRSKKLAEALERIH
HHHHHHHHHHHHHCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SENPLLFTYKKQNTIGIHTCLEVHKTSISDMLIQRLSEMQISIDTIDKNYVRGFPKQRLL
CCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCHHHEE
KLNVSNVKEDRIEKGIRIVMEEIKQAERLNFQFKKE
EEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]