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The map label for this gene is cpdC [H]

Identifier: 118477922

GI number: 118477922

Start: 2429965

End: 2431950

Strand: Direct

Name: cpdC [H]

Synonym: BALH_2267

Alternate gene names: 118477922

Gene position: 2429965-2431950 (Clockwise)

Preceding gene: 118477921

Following gene: 118477924

Centisome position: 46.22

GC content: 34.99

Gene sequence:

>1986_bases
ATGACAGTACAAAAGGGGAGAAATATTGTTATTATGCAAAAAATGAAATGGAAGAACTATTTATGTTATTTTTTTATTCT
AATACTTCTTGGAACAGCAGTAACAGTCAAACCATCTATCTCAAAAGCTGAGGAATCTGATGTTAATATTACTTTGTTAG
GTACTGCAGATATTCATGGTAGATTTATGCCTTGGGATTATGCGCTTGATGGTGCAAATACGAGTGGAAGTTTAACGCAA
CTCTATACGGTTATAAAGAAGGTACGTCAAGAAAATCCAAATACTATATTAGTAGATGCTGGGGATACTATTCAAGGAAA
CTCAGTAGAGTTATTCAATGATCAGCCACAATCGCCAATGATGGTAGCGATGAATGCCATGGGATATGATGCTTGGGCAT
TTGGAAATCATGAATTTAACTTTGGATTAGATACATTGAAAAAAGTTAGTGAGCAATATAAGGGCAAGACATTAGCAGGA
AATATTTATAAGGAAAATGGAGAGCGTTTTCTTCCTGCATATACAATTGTTGAAAAAGGTGGAATTAAAGTCGGGATTAT
TGGTATGAATACACCAATGATTAGTGATTTTGAAAAAGGGACAGATCATTTGGATGGTTTAGTGGTGAAAAATCCAGTAG
AAGAGACAAAGAAGGCCATTAAAGAGTTAGAAGGTAAAGTAGATGTAATGGTAGGCGTTATGCATATGGGACTAGAAAAT
GAGAATGGAATCCCGGGTACTGGTGTTCAAGATATTGCGAATGCTTGTCCGGAACTAAGCGCTATTTTTGCAGCTCATAT
GCATAAGCTTGTTAAAAAAGAAATTGTAAATGGCGTTATTATTACAGAACCAGATAAATATGGAACGCATATCTCACGTA
TTGACCTGACTTTTACAAAGCAAGATGGAAAGCTGGTTTTAAAAGATAAAACTGCTACCGCTATACCTGTAAAAAATACT
GATGGAACAATAGTAGTATCTGATCCTACACTTGAAGACACACTTACACCTTTTCACGAGTATGCGAGGGGAGATGCAAA
TGTTGTAGTCGCTCAATTAAAGGGTAGAAACCTTGTTCCTGAAAATGAAATAAAAGGTATTCCAAGTGTGCAGATTCAAG
AAACACCTTTATCAGATTTCTTTCATGAAGTCATGCTTTACTACAGCAAAGCAGATGTAGTCGCTCATCAAATTGATAAC
GATAATGCCCGTTTGGATGTAGGTCCTATTAAGAAAAAAGATATTGCATATAATTATCAATATGCTTTGGGTGAAATAAC
GGTATATAAGGTAACTGGGAAAGACTTAAAAGACTATATGGAATGGGCAGCAGGGTACTTTAATTCATCTCGTCCTGGAG
ATGTAACAGTTAGCTTTGATAAAACCCGTCGTGCGTCTAAATACAGTACGAATGATTTCTTTGGAGGCGTAAAATACGAA
ATTGACTTAACAAAACCATATGGAAGTAGAATAACAAATTTACGTTCTATTCGTACAAATAAACCAATCAAAACGAATGA
TGTTATGACGCTGGGAATGAATGCGTATAGAATGGAGGCTCTTCAGGCGAAAGGTGGAGCTTTAGAGGGGCGTAAGTTTG
AACAAATTTGGTCATCTAAACAAGAGAATGCATTCGGGGAAACTGGTGGAACCATTCGTAACCTTGCTATTACATATTTA
AAAGAGGTGAAGAACGGTGTTTACACACCAAAAGTTATGCATAATTGGAAAATTACTGGCGTGAATACACATTCTTCAGA
GCATAAGGCTGTAGTGGATCTTGTGAATAAAGGGATTTTAGAAATTCCAAAAACTGAAGATGGAAAATATACAAACATAG
CATCTATAAATACTAAAGATTCAATTACAAAAGAAGAGATTGTAGCAATCTCACAAAAAGCAAATATTAATCCAAATCAG
TTTAAGCACATAAAAACGAAAGGTGAATTTTACAAAAAACTTAGTAGAATTGTAAAAAAAATATAA

Upstream 100 bases:

>100_bases
TATCATTTTTTGTTTTTCATGCAGAATCACCCGCAAAATTACTTTTTGTAGTTGAAGTTTTCCGAATAATAAGTTACATT
TTTAAGGTTCAAGCAACTAT

Downstream 100 bases:

>100_bases
GAAACATGACTCTAGTGCAAAAAAGTTATAACTAGAAATTTAAATATATACGCAAAAAAGAGCACTCCTATACATGGCGA
TAGGATGCTCTTTTTTATGT

Product: 2',3'-cyclic-nucleotide 2'-phosphodiesterase

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MTVQKGRNIVIMQKMKWKNYLCYFFILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQ
LYTVIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAG
NIYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
ENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEIVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNT
DGTIVVSDPTLEDTLTPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDN
DNARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRPGDVTVSFDKTRRASKYSTNDFFGGVKYE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYL
KEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVAISQKANINPNQ
FKHIKTKGEFYKKLSRIVKKI

Sequences:

>Translated_661_residues
MTVQKGRNIVIMQKMKWKNYLCYFFILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQ
LYTVIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAG
NIYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
ENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEIVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNT
DGTIVVSDPTLEDTLTPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDN
DNARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRPGDVTVSFDKTRRASKYSTNDFFGGVKYE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYL
KEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVAISQKANINPNQ
FKHIKTKGEFYKKLSRIVKKI
>Mature_660_residues
TVQKGRNIVIMQKMKWKNYLCYFFILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQL
YTVIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGN
IYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLENE
NGIPGTGVQDIANACPELSAIFAAHMHKLVKKEIVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNTD
GTIVVSDPTLEDTLTPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDND
NARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRPGDVTVSFDKTRRASKYSTNDFFGGVKYEI
DLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYLK
EVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVAISQKANINPNQF
KHIKTKGEFYKKLSRIVKKI

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=228, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790658, Length=636, Percent_Identity=25.1572327044025, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786687, Length=456, Percent_Identity=25.4385964912281, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 73599; Mature: 73468

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQKGRNIVIMQKMKWKNYLCYFFILILLGTAVTVKPSISKAEESDVNITLLGTADIHG
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCC
RFMPWDYALDGANTSGSLTQLYTVIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPM
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCE
MVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAYTIVEKG
EEEEECCCCCEEEECCCEECCCHHHHHHHHHHHCCCEEECCEECCCCCEECCEEEEEECC
GIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
CEEEEEEECCCCCCCCHHCCCHHHCCEEECCCHHHHHHHHHHHCCCHHHEEEHHHHCCCC
ENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEIVNGVIITEPDKYGTHISRIDLTFTK
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCEEEEEEEEEEE
QDGKLVLKDKTATAIPVKNTDGTIVVSDPTLEDTLTPFHEYARGDANVVVAQLKGRNLVP
CCCEEEEECCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
ENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDNDNARLDVGPIKKKDIAYNYQ
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCCCCEEEEEE
YALGEITVYKVTGKDLKDYMEWAAGYFNSSRPGDVTVSFDKTRRASKYSTNDFFGGVKYE
EEECEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSK
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCC
QENAFGETGGTIRNLAITYLKEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGIL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCHHHHHHHHHCCCE
EIPKTEDGKYTNIASINTKDSITKEEIVAISQKANINPNQFKHIKTKGEFYKKLSRIVKK
ECCCCCCCCEEEEEECCCCCCCCHHHHHEECCCCCCCHHHHHEECCHHHHHHHHHHHHHC
I
C
>Mature Secondary Structure 
TVQKGRNIVIMQKMKWKNYLCYFFILILLGTAVTVKPSISKAEESDVNITLLGTADIHG
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCC
RFMPWDYALDGANTSGSLTQLYTVIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPM
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCE
MVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAYTIVEKG
EEEEECCCCCEEEECCCEECCCHHHHHHHHHHHCCCEEECCEECCCCCEECCEEEEEECC
GIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
CEEEEEEECCCCCCCCHHCCCHHHCCEEECCCHHHHHHHHHHHCCCHHHEEEHHHHCCCC
ENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEIVNGVIITEPDKYGTHISRIDLTFTK
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCEEEEEEEEEEE
QDGKLVLKDKTATAIPVKNTDGTIVVSDPTLEDTLTPFHEYARGDANVVVAQLKGRNLVP
CCCEEEEECCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
ENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDNDNARLDVGPIKKKDIAYNYQ
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCCCCCEEEEEE
YALGEITVYKVTGKDLKDYMEWAAGYFNSSRPGDVTVSFDKTRRASKYSTNDFFGGVKYE
EEECEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSK
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCC
QENAFGETGGTIRNLAITYLKEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGIL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCHHHHHHHHHCCCE
EIPKTEDGKYTNIASINTKDSITKEEIVAISQKANINPNQFKHIKTKGEFYKKLSRIVKK
ECCCCCCCCEEEEEECCCCCCCCHHHHHEECCCCCCCHHHHHEECCHHHHHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]