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The map label for this gene is penPC [H]

Identifier: 118477909

GI number: 118477909

Start: 2414603

End: 2415553

Strand: Direct

Name: penPC [H]

Synonym: BALH_2254

Alternate gene names: 118477909

Gene position: 2414603-2415553 (Clockwise)

Preceding gene: 118477908

Following gene: 118477910

Centisome position: 45.93

GC content: 38.38

Gene sequence:

>951_bases
ATGGTTAAGAACTTGAAAGGAATGATGATTTTGAAAAACAAGAGGATGCTAAAAATAGGAATATGCGTTAGTATATTAGG
TTTAAGTTTTACAAGCCTCGAAGCTTTTACAGGAGGGCCATTGCAAGTTGAAGCGAAAGAAAAGAAAGGGCAAATAAAAC
ATAAAAATCAGGCGACGCATAAAGAGTTCTCTCAACTTGAGAAAAAATTTGATGCTCGATTAGGTGTATATGCGATTAAT
ACTGGTACAAAACAAACAATCGCTTATCGACCTAACGAAAGGTTTGCTTTTGCATCAACTTACAAGGCTTTAGCGGCAGG
AGTATTACTGCAGCAAAACTCTACTATGAAATTAGATGAAGTTATTACTTATACGAAAGAAGACTTAGTGGATTATTCAC
CTGTTACAGAGAAACATGTAGATACTGGAATGACACTAGGAGAAATTGCGGAGGCTGCTGTTCGTTACAGTGATAATACT
GCAGGGAACATTTTATTTAACAAAATAGGCGGACCAAAAGGATATGAAAAAGCGCTTAGACAGATGGGTGATCGTGTTAC
TATGTCTGATCGCTTTGAAACAGAATTAAACGAGGCTATTCCAGGAGACATTCGTGACACTAGTACAGCGAAAGCAATTG
CTACGAATCTTAAAGCTTTTACGGCCGGAAATGCACTTCCAAATCATAAGCGTAACATTCTTACAGAGTGGATGAAAGGA
AATGCTACAGGAGACAAACTTATTCGTGCAGGTGTACCAACCGACTGGATAGTTGCAGATAAATCAGGGGCTGGAAGTTA
TGGGACACGAAATGATATCGCTATCGTTTGGCCGCCAAATAGAGCACCAATTATCATCGCAATTTTATCTAGTAAAGATG
AGAAAGAGGCTACCTATGATAATCAACTTATTGCAGAGGCGGCTGAAGTTATAGTTAATGCTTTTAGGTGA

Upstream 100 bases:

>100_bases
TATCTCTTATTTTGCTAATGACTCTCATACTAGCTAAAAATTTTTAAAAGTTTATGGAACAAATTTGTTTTGGTGATTGT
CTATTATGTGTACGTAAAAA

Downstream 100 bases:

>100_bases
TAATCTCTCAATTCTTTATGTAATGTAATTGAAAATATGAACTTGGAAAGCGATTCTTTTTAATGTGAAAAGAATCGCTT
TTTTTGTATTCCTAATACAT

Product: beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase I; Penicillinase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVKNLKGMMILKNKRMLKIGICVSILGLSFTSLEAFTGGPLQVEAKEKKGQIKHKNQATHKEFSQLEKKFDARLGVYAIN
TGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNT
AGNILFNKIGGPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKG
NATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYDNQLIAEAAEVIVNAFR

Sequences:

>Translated_316_residues
MVKNLKGMMILKNKRMLKIGICVSILGLSFTSLEAFTGGPLQVEAKEKKGQIKHKNQATHKEFSQLEKKFDARLGVYAIN
TGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNT
AGNILFNKIGGPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKG
NATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYDNQLIAEAAEVIVNAFR
>Mature_316_residues
MVKNLKGMMILKNKRMLKIGICVSILGLSFTSLEAFTGGPLQVEAKEKKGQIKHKNQATHKEFSQLEKKFDARLGVYAIN
TGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNT
AGNILFNKIGGPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKG
NATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYDNQLIAEAAEVIVNAFR

Specific function: Acts preferentially on penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 34704; Mature: 34704

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNLKGMMILKNKRMLKIGICVSILGLSFTSLEAFTGGPLQVEAKEKKGQIKHKNQATH
CCCCCCCEEEECCCCEEEHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
KEFSQLEKKFDARLGVYAINTGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDE
HHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHEECCCCCCHHH
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGPKGYEKALR
HHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHH
QMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKG
HHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCC
NATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYD
CCCHHHHEECCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHH
NQLIAEAAEVIVNAFR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKNLKGMMILKNKRMLKIGICVSILGLSFTSLEAFTGGPLQVEAKEKKGQIKHKNQATH
CCCCCCCEEEECCCCEEEHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
KEFSQLEKKFDARLGVYAINTGTKQTIAYRPNERFAFASTYKALAAGVLLQQNSTMKLDE
HHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHEECCCCCCHHH
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGPKGYEKALR
HHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHH
QMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTEWMKG
HHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCC
NATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKEATYD
CCCHHHHEECCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHH
NQLIAEAAEVIVNAFR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991192 [H]