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The map label for this gene is gpmA [H]

Identifier: 118477895

GI number: 118477895

Start: 2396266

End: 2397003

Strand: Direct

Name: gpmA [H]

Synonym: BALH_2240

Alternate gene names: 118477895

Gene position: 2396266-2397003 (Clockwise)

Preceding gene: 118477894

Following gene: 118477896

Centisome position: 45.58

GC content: 34.82

Gene sequence:

>738_bases
ATGATAAAACTTGTACTTATTCGTCACGGACAGAGTTTATGGAATCTTGAAAATCGTTTTACTGGATGGACAGATGTAGA
TTTATCAGAGAATGGATTAAGTGAAGCGAGAGAAGCAGGAGCGATATTAAAGAAAAATGGATATACTTTTGATGTAGCTT
ATACATCTGTATTAAAACGAGCAATTCGGACGTTATGGATTGTACTTCATGAAATGAATCTTTCCTGGGTACCAGTACAT
AAATCTTGGAAGCTAAATGAAAGACATTATGGTGCATTGCAAGGGTTAAATAAAGATGAAACAGCGAAAAAATATGGTGA
GGAGCAAGTTCATATTTGGAGAAGAAGTATTGATGTAAGACCACCTGCTCTTACTGAAGATGATCCTAGATATGAAATGA
ATGATCCAAGATATAAAGAACTGAAAAAAGGTGAGTTTCCATTGACTGAATGTTTAGTGGATACGGAGAAAAGAGTACTT
AATTATTGGCATTCAGAAATTGCGCCATCATTAAAAAGTGGTGAAAAGGTGATAATTTCATCGCACGGTAATACAATTCG
TTCGCTAGTGAAATACTTAGATAACCTTTCAAGTGATGGTGTTGTTTCATTAAATATTCCAACAAGCATTCCGCTCGTTT
ATGAATTAGACGATGATTTACGTCCAATTCGTCATTATTATTTAAGCATGGACGGAGAAGTACCAGAAGGGGAATTTCCG
AAACACATTGTTTTTTAA

Upstream 100 bases:

>100_bases
AGCTATCATAGAGTAAATGGATAAAAAGATACATTACTAGATACTTTATACGTGTACGCAATGGAACAATAAAATTCACA
TTTCCGAGAGGGGAATTATA

Downstream 100 bases:

>100_bases
CATGAAAATTTGAAACGTATGCTTGTCTACATATACAATGTAGATTCAGGATAAAAGACGTGGTACCTTCTAATGTATAT
GCGATATTGCTAAGTTTAGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLSWVPVH
KSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVL
NYWHSEIAPSLKSGEKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFP
KHIVF

Sequences:

>Translated_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLSWVPVH
KSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVL
NYWHSEIAPSLKSGEKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFP
KHIVF
>Mature_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLSWVPVH
KSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVL
NYWHSEIAPSLKSGEKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFP
KHIVF

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=234, Percent_Identity=50, Blast_Score=255, Evalue=2e-68,
Organism=Homo sapiens, GI4505753, Length=234, Percent_Identity=52.991452991453, Blast_Score=249, Evalue=1e-66,
Organism=Homo sapiens, GI71274132, Length=234, Percent_Identity=50.4273504273504, Blast_Score=235, Evalue=3e-62,
Organism=Homo sapiens, GI4502445, Length=243, Percent_Identity=43.2098765432099, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI40353764, Length=243, Percent_Identity=43.2098765432099, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=56.875, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI1786970, Length=234, Percent_Identity=62.3931623931624, Blast_Score=313, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=50.6550218340611, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6324516, Length=277, Percent_Identity=31.7689530685921, Blast_Score=128, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6320183, Length=283, Percent_Identity=29.6819787985866, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=51.7857142857143, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=51.7857142857143, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=51.7857142857143, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24646216, Length=224, Percent_Identity=50.8928571428571, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI28571815, Length=218, Percent_Identity=39.4495412844037, Blast_Score=173, Evalue=9e-44,
Organism=Drosophila melanogaster, GI28571817, Length=218, Percent_Identity=39.4495412844037, Blast_Score=173, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24648979, Length=218, Percent_Identity=39.4495412844037, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28362; Mature: 28362

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMNLSWVPVHKSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVLNYWHSEIAPSLKSGEKVIIS
CCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCC
KHIVF
CCCCC
>Mature Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMNLSWVPVHKSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVLNYWHSEIAPSLKSGEKVIIS
CCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCC
KHIVF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA