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The map label for this gene is ipdC [H]

Identifier: 118477893

GI number: 118477893

Start: 2394657

End: 2395178

Strand: Reverse

Name: ipdC [H]

Synonym: BALH_2238

Alternate gene names: 118477893

Gene position: 2395178-2394657 (Counterclockwise)

Preceding gene: 118477897

Following gene: 118477886

Centisome position: 45.56

GC content: 32.57

Gene sequence:

>522_bases
ATGGAAAATGGAGAGCTCGTTCATCATACGTTAGGCGACGGAAAGTTTAATCACTTTTCCAATATGTATCGAGAAATTAC
TGTTGCACAAACTAATTTAACCCCAGAGCATGCAGTCGAGGAAATTGACCGTGTGTTACGTGCATGTTGGAATGAAAAAC
GTCCTGTTCATATTCATTTGCCGATTGATGTGTATAATAAACCAATTAATAAACCTGCAGAACCAATTTTACATAAACCG
ATTTTAAATAATAAAGAAACACTGGATAAAATGCTTCTACATGCCATTTCAAAAATAAATAGCGCAAAGAAACCTATTAT
TTTAGCTGATTTTGAAGTAGATCGTTTTCATGCAAAAGAATATTTATATCAATTTGTAGAAAAAACGTGGTTTCCTATTG
CAACGTTAAGTATGGGAAAAGGAATATTTCCAGAAAAACACCCTCAATTTATAGGGATTTATACTGGTGATATTAAGACG
GTTTTTATGAGCATTTCGTATAAGTGTGATTTAACTGATTAA

Upstream 100 bases:

>100_bases
CTTTGGCGTTGGAGAATTAAGTGCCATTAACGGAATTGCTGGTTCATATGCTGAAAATGTACCCGTTATAAAAATAACAG
GTACGCCAACAACAACTGTA

Downstream 100 bases:

>100_bases
GACTATTTTTAAAAACGACATATCAGCGATAATTTATGTCTATTCTGTATAAGTGTTAGCAAGATTGTTTGCAAACTTGT
TAGCACTTTTAAAACATAAA

Product: indolepyruvate decarboxylase, N-terminal

Products: NA

Alternate protein names: Indolepyruvate decarboxylase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MENGELVHHTLGDGKFNHFSNMYREITVAQTNLTPEHAVEEIDRVLRACWNEKRPVHIHLPIDVYNKPINKPAEPILHKP
ILNNKETLDKMLLHAISKINSAKKPIILADFEVDRFHAKEYLYQFVEKTWFPIATLSMGKGIFPEKHPQFIGIYTGDIKT
VFMSISYKCDLTD

Sequences:

>Translated_173_residues
MENGELVHHTLGDGKFNHFSNMYREITVAQTNLTPEHAVEEIDRVLRACWNEKRPVHIHLPIDVYNKPINKPAEPILHKP
ILNNKETLDKMLLHAISKINSAKKPIILADFEVDRFHAKEYLYQFVEKTWFPIATLSMGKGIFPEKHPQFIGIYTGDIKT
VFMSISYKCDLTD
>Mature_173_residues
MENGELVHHTLGDGKFNHFSNMYREITVAQTNLTPEHAVEEIDRVLRACWNEKRPVHIHLPIDVYNKPINKPAEPILHKP
ILNNKETLDKMLLHAISKINSAKKPIILADFEVDRFHAKEYLYQFVEKTWFPIATLSMGKGIFPEKHPQFIGIYTGDIKT
VFMSISYKCDLTD

Specific function: Catalyzes The Condensation Of Two Molecules Of Glyoxylate To Give 2-Hydroxy-3-Oxopropanoate (Also Termed Tartronate Semialdehyde). [C]

COG id: COG3961

COG function: function code GHR; Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323163, Length=160, Percent_Identity=33.75, Blast_Score=91, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323073, Length=160, Percent_Identity=33.125, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320123, Length=161, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321524, Length=159, Percent_Identity=30.8176100628931, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017764
- InterPro:   IPR012110
- InterPro:   IPR012000
- InterPro:   IPR012001
- InterPro:   IPR000399
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF00205 TPP_enzyme_M; PF02776 TPP_enzyme_N [H]

EC number: =4.1.1.74 [H]

Molecular weight: Translated: 20040; Mature: 20040

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGELVHHTLGDGKFNHFSNMYREITVAQTNLTPEHAVEEIDRVLRACWNEKRPVHIHL
CCCCCEEEEECCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
PIDVYNKPINKPAEPILHKPILNNKETLDKMLLHAISKINSAKKPIILADFEVDRFHAKE
CHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
YLYQFVEKTWFPIATLSMGKGIFPEKHPQFIGIYTGDIKTVFMSISYKCDLTD
HHHHHHHHHCCCCEEHHCCCCCCCCCCCCEEEEEECCCEEEEEEEEEEEECCC
>Mature Secondary Structure
MENGELVHHTLGDGKFNHFSNMYREITVAQTNLTPEHAVEEIDRVLRACWNEKRPVHIHL
CCCCCEEEEECCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
PIDVYNKPINKPAEPILHKPILNNKETLDKMLLHAISKINSAKKPIILADFEVDRFHAKE
CHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
YLYQFVEKTWFPIATLSMGKGIFPEKHPQFIGIYTGDIKTVFMSISYKCDLTD
HHHHHHHHHCCCCEEHHCCCCCCCCCCCCEEEEEECCCEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2034209 [H]