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The map label for this gene is pagR [H]

Identifier: 118477766

GI number: 118477766

Start: 2254858

End: 2255157

Strand: Direct

Name: pagR [H]

Synonym: BALH_2104

Alternate gene names: 118477766

Gene position: 2254858-2255157 (Clockwise)

Preceding gene: 118477765

Following gene: 118477768

Centisome position: 42.89

GC content: 29.67

Gene sequence:

>300_bases
ATGACAACATATACGAGTGAAATGAGAAAAAGTTTAGTTTCAGAAGAAGATGTAGATATTTTAAAAATTATGGCGCACCC
AATTCGATTACAAATCGTAAATGAATTAAGCACGAGAAAGACTTGTAACGTAACACAACTAACAGAATTACTAAATATTC
CACAATCGACTGTTTCGCAACATTTATCAAAAATGAAGGGTAAAGTGTTACGAGCTGAGAGAAGAGGTTTAGAAATTTAT
TATCATATTAACAATTTAAAAGCGAGTAAGATTGTAAGTGTTTTAGGATATATAAACTAA

Upstream 100 bases:

>100_bases
TAAAATTCTATTATTTTTATATAAAGGTTTCACATCGGAGTTTTAAATATTTTGGAAATAGATCTAAATAAAAGGAATTC
ATATAAAAGGGGAATGTCTT

Downstream 100 bases:

>100_bases
TGAAGTATTTTCATATAAAATAGCCGCTGCTGGTAAGCAGGGGCTATTTTGTGTTGTTTTATCCCGCGTTAACGGACAGT
AAAACTTCTACCTCAAAATT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MTTYTSEMRKSLVSEEDVDILKIMAHPIRLQIVNELSTRKTCNVTQLTELLNIPQSTVSQHLSKMKGKVLRAERRGLEIY
YHINNLKASKIVSVLGYIN

Sequences:

>Translated_99_residues
MTTYTSEMRKSLVSEEDVDILKIMAHPIRLQIVNELSTRKTCNVTQLTELLNIPQSTVSQHLSKMKGKVLRAERRGLEIY
YHINNLKASKIVSVLGYIN
>Mature_98_residues
TTYTSEMRKSLVSEEDVDILKIMAHPIRLQIVNELSTRKTCNVTQLTELLNIPQSTVSQHLSKMKGKVLRAERRGLEIYY
HINNLKASKIVSVLGYIN

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11345; Mature: 11213

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYTSEMRKSLVSEEDVDILKIMAHPIRLQIVNELSTRKTCNVTQLTELLNIPQSTVSQ
CCCCHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
HLSKMKGKVLRAERRGLEIYYHINNLKASKIVSVLGYIN
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTYTSEMRKSLVSEEDVDILKIMAHPIRLQIVNELSTRKTCNVTQLTELLNIPQSTVSQ
CCCHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
HLSKMKGKVLRAERRGLEIYYHINNLKASKIVSVLGYIN
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]