BacMap

Definition	Bacillus thuringiensis str. Al Hakam chromosome, complete genome.
Accession	NC_008600
Length	5,257,091

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The map label for this gene is yoxD [H]

Identifier: 118477748

GI number: 118477748

Start: 2231952

End: 2232659

Strand: Direct

Name: yoxD [H]

Synonym: BALH_2085

Alternate gene names: 118477748

Gene position: 2231952-2232659 (Clockwise)

Preceding gene: 118477747

Following gene: 118477749

Centisome position: 42.46

GC content: 37.71

Gene sequence:

>708_bases
TTGAAACAAAAAAGCAGTGGGAAAAGTGTAATTATTACAGGCGTGACGCAAGGGTTAGGCCGTGCAATGGTTGATCGATT
TCATGAATTGGGATGGAATATATATGGCTGTGGACGTTCAAAAGATAAAATTGAAGAATTAAAAAAATATTACGGTAATA
CACATGTTTTTCAAATAATTGATGTTTCAGATTCTCAGCAAGTAAGTGATTGGGCAAATTATATACTTCATAGAAATAGA
GCGCCTGATTTGTTAATAAATAATGCATCGATTGTTAATAAAAATGCGCCACTCTGGAAAGTAACTGCTGAAGAATTCGA
AAATGTAATGAATGTAAACGTAAATGGTGTAGTAAATGTAATAAGAGCATTTGTCCCAGCAATGGTAGCCAGGAAAGCAG
GAATGATTATTAATATGAGTTCTAGTTGGGGGAGAGAAGGAGAAGCAGAGCTGGCGCCATATTGTGCCTCAAAGTTTGCG
ATTGAAGGCATCACGAAATCTTTGGCACTTGAATTGCCCTATAGTATGGCTGTTGTTGCTTTAGATCCGGGCGGAAGTAT
TAGCACTCCGATGCTGTATTCGTGTGCACCACAGTATGTAAACGAGTCCCCTACACCTGAAATGTGGTCACAACATGCGA
TTCCATATATATTAAAGATAACAATAGATAAAAATGGAGCTTCATTGACATGCCCAGAATGTACGTAA

Upstream 100 bases:

>100_bases
TTATATAAAAACTCCTTCTAAAGTATGAAATGAGTTGATACTTTAGTAATTGGCTGAAGGAAAAAGAAGATAATAAAATA
TTGGAAAGGAGGAGAGAGAC

Downstream 100 bases:

>100_bases
ATATATATTGAATTGTCATATTTTTAATGATACACGCTTTGTCTAAAAAAGTACCTTTAATGAAAGATTGAAAGAGAATG
ATTATCTCATAATTGTCGGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKQKSSGKSVIITGVTQGLGRAMVDRFHELGWNIYGCGRSKDKIEELKKYYGNTHVFQIIDVSDSQQVSDWANYILHRNR
APDLLINNASIVNKNAPLWKVTAEEFENVMNVNVNGVVNVIRAFVPAMVARKAGMIINMSSSWGREGEAELAPYCASKFA
IEGITKSLALELPYSMAVVALDPGGSISTPMLYSCAPQYVNESPTPEMWSQHAIPYILKITIDKNGASLTCPECT

Sequences:

>Translated_235_residues
MKQKSSGKSVIITGVTQGLGRAMVDRFHELGWNIYGCGRSKDKIEELKKYYGNTHVFQIIDVSDSQQVSDWANYILHRNR
APDLLINNASIVNKNAPLWKVTAEEFENVMNVNVNGVVNVIRAFVPAMVARKAGMIINMSSSWGREGEAELAPYCASKFA
IEGITKSLALELPYSMAVVALDPGGSISTPMLYSCAPQYVNESPTPEMWSQHAIPYILKITIDKNGASLTCPECT
>Mature_235_residues
MKQKSSGKSVIITGVTQGLGRAMVDRFHELGWNIYGCGRSKDKIEELKKYYGNTHVFQIIDVSDSQQVSDWANYILHRNR
APDLLINNASIVNKNAPLWKVTAEEFENVMNVNVNGVVNVIRAFVPAMVARKAGMIINMSSSWGREGEAELAPYCASKFA
IEGITKSLALELPYSMAVVALDPGGSISTPMLYSCAPQYVNESPTPEMWSQHAIPYILKITIDKNGASLTCPECT

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=185, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI44680136, Length=223, Percent_Identity=25.1121076233184, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI44680133, Length=223, Percent_Identity=25.1121076233184, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI17738292, Length=223, Percent_Identity=25.1121076233184, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705925, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI150247226, Length=180, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI22507405, Length=182, Percent_Identity=29.1208791208791, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40807363, Length=176, Percent_Identity=32.9545454545455, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=27.5132275132275, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI142976729, Length=204, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4504503, Length=186, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=30.9178743961353, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=226, Percent_Identity=21.6814159292035, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI31542939, Length=175, Percent_Identity=29.1428571428571, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40548397, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010158, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010156, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI22758144, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=209, Percent_Identity=33.4928229665072, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=28.2608695652174, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=28.3505154639175, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788891, Length=238, Percent_Identity=31.9327731092437, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=184, Percent_Identity=28.804347826087, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=27.9569892473118, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=174, Percent_Identity=32.7586206896552, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=176, Percent_Identity=33.5227272727273, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=175, Percent_Identity=32, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=177, Percent_Identity=31.0734463276836, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=204, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17557780, Length=193, Percent_Identity=29.0155440414508, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=219, Percent_Identity=30.5936073059361, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=171, Percent_Identity=27.4853801169591, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557668, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=181, Percent_Identity=25.414364640884, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=186, Percent_Identity=26.8817204301075, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=201, Percent_Identity=29.3532338308458, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=186, Percent_Identity=27.9569892473118, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=28.125, Blast_Score=88, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281364892, Length=176, Percent_Identity=34.6590909090909, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=184, Percent_Identity=33.1521739130435, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24640492, Length=172, Percent_Identity=29.6511627906977, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571526, Length=182, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21358495, Length=173, Percent_Identity=28.9017341040462, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581726, Length=173, Percent_Identity=30.635838150289, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25877; Mature: 25877

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKSSGKSVIITGVTQGLGRAMVDRFHELGWNIYGCGRSKDKIEELKKYYGNTHVFQII
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEE
DVSDSQQVSDWANYILHRNRAPDLLINNASIVNKNAPLWKVTAEEFENVMNVNVNGVVNV
ECCCCHHHHHHHHHHHHCCCCCCEEECCCEEECCCCCEEEEEHHHHHHHHCCCHHHHHHH
IRAFVPAMVARKAGMIINMSSSWGREGEAELAPYCASKFAIEGITKSLALELPYSMAVVA
HHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEE
LDPGGSISTPMLYSCAPQYVNESPTPEMWSQHAIPYILKITIDKNGASLTCPECT
ECCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCEEECCCCC
>Mature Secondary Structure
MKQKSSGKSVIITGVTQGLGRAMVDRFHELGWNIYGCGRSKDKIEELKKYYGNTHVFQII
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEE
DVSDSQQVSDWANYILHRNRAPDLLINNASIVNKNAPLWKVTAEEFENVMNVNVNGVVNV
ECCCCHHHHHHHHHHHHCCCCCCEEECCCEEECCCCCEEEEEHHHHHHHHCCCHHHHHHH
IRAFVPAMVARKAGMIINMSSSWGREGEAELAPYCASKFAIEGITKSLALELPYSMAVVA
HHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCEEEEEE
LDPGGSISTPMLYSCAPQYVNESPTPEMWSQHAIPYILKITIDKNGASLTCPECT
ECCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849493; 9384377; 3118336 [H]