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The map label for this gene is aspC [H]

Identifier: 118477616

GI number: 118477616

Start: 2093743

End: 2095041

Strand: Direct

Name: aspC [H]

Synonym: BALH_1944

Alternate gene names: 118477616

Gene position: 2093743-2095041 (Clockwise)

Preceding gene: 118477615

Following gene: 118477617

Centisome position: 39.83

GC content: 34.8

Gene sequence:

>1299_bases
ATGGGGCAAATCATGAAACGTTCACTCACAAAAGAATGTACGGAGAAAAGCGGAAAGGTTGTATCACTTCAAGGCTGGGT
AAAAAAGATTCGTCATCTAGGTAATGTTAGTTTTTTATTATTACGGGACAGAACAGGAGTCATTCAATGTGTATTAGAAA
ACGAATTCGCTGGATTCAAAGTTGATGTAGAAAGTATTGTTCACGTAATTGGTGAAATAGTTGAAACGTCAAAAACAGAA
TTAGGCGTAGAAGTGCTTGCTCACGAAGTGAAAATATTAAATGGGACAGAACCACTTCCATTTGAAATAAATAAAAAGAA
GTTACAAGTTGGCTTAGATCAACTACTGAATGAACGGGTATTATCATTAAGACATGAGCGAACCGCGTCTATATTTAAAG
TGAAATCTACGCTCGTCCAGAGCTTTAGTGAATTCCTTATAGAGAACGATTTCACACGTATATTTACTCCAAAAATTGTT
TCGCAAGGGGCAGAAGGAGGAGCAAATGTTTTTAAGTTGCCATACTTCCAAAAAGAAGCGTATTTAGCTCAATCACCACA
GTTTTATAAGCAAATGATGGTAGCGGGAGGATTAGAACGTGTTTTTGAAATTGCACCTGTATATAGAGCGGAACATCACA
ATTCTTCCCGTCATTTAAATGAATATATATCGTTAGACGTAGAGATTGGCTTTATAAATGATTTTCATGAAGTGATGCAA
TTAGAAACGGATGTATTACGATATATGTTTCAACAAGTAGCAAAAAACTGTGAGAAAGAACTACAACTATTACAAATAGA
AGTACCTGTTATTACAGAAATACCGAAAATTACATTGTTACAAGCACAAGAAATTTTGAAAATTAAGTATCGGAAAGAAT
CGCCAATTGGGGATTTAGATACAGAAGGTGAGAAGTTACTAGGGAAATATGTGAAGGAAACATATAAGAGTGAATTTGTT
TTCATTACACATTATCCGAAAGAAGCGAGACCGATGTATACGATGCCGAATAACGAGAATCCATCTATTACTGATTCGTT
CGACTTACTATATAAAGGATTAGAAATAACATCAGGGGCACAGCGAATTCATAATTATGAAATGTTACTAACTTCCTTTA
AAGAAAAAGGATTACATCCAGATAAATTTCAATCTTATTTAAATACATTCCGATATGGTTGTCCCCCGCACGGTGGTTTT
GGAATTGGATTAGAGAGAGTTGTATATAAATTTTTAGAATTATCGAATGTGAGAGAAGCGAGTGCTTTTCCAAGAGATTG
TACGCGTCTTATACCATAA

Upstream 100 bases:

>100_bases
CGGATTTTTGTATTCTTTGAAAGGGGGTGAGTGACCGTGGATGATGACGATGACAACAACAATAACGTAAATAAATATAA
AATTACTGGAGGGAAATGTA

Downstream 100 bases:

>100_bases
CATGAGTACCCTTCTATAGTATAGAAGGGTACTTTGCATTTTAATAAAAGTGGAAGAGAATAATAATATTTTTTGTGTGA
AAATATGTAAATTATATTAA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MGQIMKRSLTKECTEKSGKVVSLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGFKVDVESIVHVIGEIVETSKTE
LGVEVLAHEVKILNGTEPLPFEINKKKLQVGLDQLLNERVLSLRHERTASIFKVKSTLVQSFSEFLIENDFTRIFTPKIV
SQGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVEIGFINDFHEVMQ
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLQAQEILKIKYRKESPIGDLDTEGEKLLGKYVKETYKSEFV
FITHYPKEARPMYTMPNNENPSITDSFDLLYKGLEITSGAQRIHNYEMLLTSFKEKGLHPDKFQSYLNTFRYGCPPHGGF
GIGLERVVYKFLELSNVREASAFPRDCTRLIP

Sequences:

>Translated_432_residues
MGQIMKRSLTKECTEKSGKVVSLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGFKVDVESIVHVIGEIVETSKTE
LGVEVLAHEVKILNGTEPLPFEINKKKLQVGLDQLLNERVLSLRHERTASIFKVKSTLVQSFSEFLIENDFTRIFTPKIV
SQGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVEIGFINDFHEVMQ
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLQAQEILKIKYRKESPIGDLDTEGEKLLGKYVKETYKSEFV
FITHYPKEARPMYTMPNNENPSITDSFDLLYKGLEITSGAQRIHNYEMLLTSFKEKGLHPDKFQSYLNTFRYGCPPHGGF
GIGLERVVYKFLELSNVREASAFPRDCTRLIP
>Mature_431_residues
GQIMKRSLTKECTEKSGKVVSLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGFKVDVESIVHVIGEIVETSKTEL
GVEVLAHEVKILNGTEPLPFEINKKKLQVGLDQLLNERVLSLRHERTASIFKVKSTLVQSFSEFLIENDFTRIFTPKIVS
QGAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVEIGFINDFHEVMQL
ETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLQAQEILKIKYRKESPIGDLDTEGEKLLGKYVKETYKSEFVF
ITHYPKEARPMYTMPNNENPSITDSFDLLYKGLEITSGAQRIHNYEMLLTSFKEKGLHPDKFQSYLNTFRYGCPPHGGFG
IGLERVVYKFLELSNVREASAFPRDCTRLIP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI45439306, Length=456, Percent_Identity=36.1842105263158, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI4758762, Length=431, Percent_Identity=29.6983758700696, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=27.6255707762557, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI40789249, Length=235, Percent_Identity=30.6382978723404, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787161, Length=450, Percent_Identity=27.3333333333333, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1790571, Length=450, Percent_Identity=26, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789256, Length=448, Percent_Identity=25.6696428571429, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788173, Length=252, Percent_Identity=26.1904761904762, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17551876, Length=459, Percent_Identity=37.9084967320261, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI71984122, Length=441, Percent_Identity=26.984126984127, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17556372, Length=402, Percent_Identity=26.6169154228856, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32566633, Length=324, Percent_Identity=27.1604938271605, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323011, Length=454, Percent_Identity=36.1233480176211, Blast_Score=283, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=442, Percent_Identity=30.0904977375566, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6319872, Length=475, Percent_Identity=26.9473684210526, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325153, Length=242, Percent_Identity=28.099173553719, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17136276, Length=455, Percent_Identity=36.2637362637363, Blast_Score=287, Evalue=9e-78,
Organism=Drosophila melanogaster, GI19921528, Length=436, Percent_Identity=27.9816513761468, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19922416, Length=451, Percent_Identity=23.5033259423503, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24584738, Length=247, Percent_Identity=32.7935222672065, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640851, Length=460, Percent_Identity=22.6086956521739, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640849, Length=460, Percent_Identity=22.6086956521739, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 49554; Mature: 49423

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQIMKRSLTKECTEKSGKVVSLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGFK
CCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCE
VDVESIVHVIGEIVETSKTELGVEVLAHEVKILNGTEPLPFEINKKKLQVGLDQLLNERV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LSLRHERTASIFKVKSTLVQSFSEFLIENDFTRIFTPKIVSQGAEGGANVFKLPYFQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCCCCCCCCEEECCCHHHHH
YLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVEIGFINDFHEVMQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECHHHHHHHHH
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLQAQEILKIKYRKESPIGDLD
HHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC
TEGEKLLGKYVKETYKSEFVFITHYPKEARPMYTMPNNENPSITDSFDLLYKGLEITSGA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHCCHHCCHH
QRIHNYEMLLTSFKEKGLHPDKFQSYLNTFRYGCPPHGGFGIGLERVVYKFLELSNVREA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SAFPRDCTRLIP
CCCCHHHHHCCC
>Mature Secondary Structure 
GQIMKRSLTKECTEKSGKVVSLQGWVKKIRHLGNVSFLLLRDRTGVIQCVLENEFAGFK
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCE
VDVESIVHVIGEIVETSKTELGVEVLAHEVKILNGTEPLPFEINKKKLQVGLDQLLNERV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LSLRHERTASIFKVKSTLVQSFSEFLIENDFTRIFTPKIVSQGAEGGANVFKLPYFQKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCCCCCCCCEEECCCHHHHH
YLAQSPQFYKQMMVAGGLERVFEIAPVYRAEHHNSSRHLNEYISLDVEIGFINDFHEVMQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECHHHHHHHHH
LETDVLRYMFQQVAKNCEKELQLLQIEVPVITEIPKITLLQAQEILKIKYRKESPIGDLD
HHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC
TEGEKLLGKYVKETYKSEFVFITHYPKEARPMYTMPNNENPSITDSFDLLYKGLEITSGA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHCCHHCCHH
QRIHNYEMLLTSFKEKGLHPDKFQSYLNTFRYGCPPHGGFGIGLERVVYKFLELSNVREA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SAFPRDCTRLIP
CCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]