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The map label for this gene is ileS [H]

Identifier: 118477612

GI number: 118477612

Start: 2087173

End: 2090274

Strand: Direct

Name: ileS [H]

Synonym: BALH_1940

Alternate gene names: 118477612

Gene position: 2087173-2090274 (Clockwise)

Preceding gene: 118477611

Following gene: 118477613

Centisome position: 39.7

GC content: 37.69

Gene sequence:

>3102_bases
ATGAAGAAAGTAGATGTAAAAGAGTCAGCTGTAGGGAGAGAAACACGTATTCGTAAACAGTGGAACGAGCAAAGTATTTT
CGAGCAATCAATTCAGAATCGAGAAGGCGCACAATCTTTTGTGTTTTATGAAGGACCACCGACGGCGAATGGATTACCGC
ATGTAGGTCATGCACTTGGACGAACAATTAAAGATGTAGTAGCAAGATATAAAACGATGGTTGGTTATAAAGTATTAAGA
AAAGCGGGATGGGATACGCACGGCTTACCTGTAGAATTAGGTGTTGAGAAGCAACTCGGTATTTCTGGTAAACATGAAAT
CGAGGAGTATGGAATTGAGCCATTTATTCAGAAGTGTAAAGAGAGTGTATTCACATATGAGAAGCAGTGGCGTGAATTCA
CCGAAAGCATCGGTTATTGGGTAGATATGGATGATCCATATGTTACGTTAGAGAATCCATATATCGAAAGTGTATGGCAT
ATTTTAGGAACGATTCATGAAAAAGGATTGTTATATAAAGGGCATAGAGTTTCGCCATACTGCCCAAGCTGTCAAACTTC
ACTAAGTTCACATGAGGTTGCACAAGGGTATAAAACAGTAAAAGATTTAAGTGCAACCGTTAAGTTTGAAGTGAAAGATA
GTGAAAATGAGTATTTCCTAGGTTGGACAACAACACCTTGGACACTTCCAGCAAATGTTGCGCTCGCTGTACATCCAAAT
ATGGAATACGTGAAAGCGAAACAAGAGGGGCATGTATACATTGTTGCGAAAGAACGTGTACAAGATGTATTAAAAGAAGA
CTATGAAGTATTATCTGTTCATAAAGGTGAAGAATTAGTAAATACATCTTATATGCCGCCATTTCCAATGAAGGAAGTTA
CAAATGGTTACCACGTTATCGCAGCGGATTTTGTCACGGCAGATAGTGGTACAGGACTCGTTCATATCGCTCCAGCATAC
GGGGAGGACGATTATAGAGTCGTTCAAAGTGAAGGATTGTCATTCTTGCATGTTGTAGATGAGAAAGGCGAGTATACAGA
AGCAGTTCCATTTTTGAAAGGGAAGTTTGTAAAAGATTGTGACGTGGATATCGTTCGTTATTTAGCGAAGGAAGGCTTAC
TATACCATAAAGAAAAGTATGAACATAGCTACCCACATTGCTGGCGCTGTGATTCACCACTTCTTTATTATGCAGGAGAG
AGTTGGTTAATCCGAACAACTGCAATTAAAGATACATTTTTACAAAATAACGATTCTGTTACTTGGTATCCAGATCATAT
GAAACATGGACGCTTCGGTAAGTTTTTAGAAAATATGGTGGACTGGAATATTAGTCGAAATAGATATTGGGGAACACCAT
TAAACGTATGGGAATGTGAAAGTTGCGATCATCAATTTGCACCAAAAAGCATTGCTGATTTAAGAAAGCATAGTACGAAA
GAAACACCGGAAGATTTAGAATTGCATAAGCCGTATGTAGATGAAGTGCAAGTTTGCTGCGAAAAATGCGGTGGCACAAT
GACTCGTACACCAGAAGTAATTGATGTTTGGTTTGATAGTGGTTCGATGCCATTTGCGCAATATCATTATCCGTTTGAAA
ATAAAGAGCTATTTGAAGAGCAGTTTCCAGCAGATGTAATTGCAGAAGGAATTGATCAAACACGCGGCTGGTTTTATAGT
TTATTAGCTGTATCAGCACTATATACAGGAAAAGCACCGTATAAACGAGTGTTATCACTAGGGCATGTTCTAGATGAAGA
AGGACAGAAAATGTCTAAAAGTAAAGGGAATGCACTAGATCCAGTTGATTTAGTAGAGAAGTTTGGTGCAGATGCTTTAA
GGTGGGCTCTACTTGTTGATAGTGCTCCGTGGAATGCGAAACGTTTCTCTGAAAGAACAGTACTGGAAGCGAAATCTAAA
TTTGTAGATACGTTAATCAATGTGTATAGCTTCTACGTTTTATATGCAAATTTAGATGAGTATAATCCGCATGAAACATA
TGACGTAAAGCGGACGAAATTGGATGAATGGGTATTATCAAGATTGCATAGCACAACGAAAAAAGTAAGAACAGCACTTG
ATGATTATCAATTTACGAATGCAGCTCGTGAAATTGCGGCACTTGTAGATGAAGTAAGTAACTGGTACGTAAGACGATCA
CGTAATCGTTTCTGGGAATCTGGTATGAATGCTGAAAAAGCAGCTGCGTATGAGACACTTCACGAAGTGCTTGTGACAAT
TAGTAAATTAATTGCACCGTTTACACCGTTTGTAGCTGAAGATATTCATGTGAATTTAACTGGAAATAGTGTTCATTTAG
AGGATTATCCAGTCGTAAATGAATCGCTACTTCAGCCTAAATTAGAAGCAGAAATGAATGCTGTTTTACAAGTTGTTGAA
CTTGGAAGAAGTAACCGTAATCAGCATTCTTTAAAAGTAAAACAGCCGTTAGCGGAACTTGTACTACTTGAGCATAATGA
AAATGATATGGACTGGGAATCTTATCGTGATATCGTCATGGATGAGTTAAATGTGAAGACGTTCCATGTTGAACTCGATG
AAACGAAATATACATCTTATCAATTAAAACTGAATTTTAAAAAGGCTGGGCCGAAGTTCGGTAAAAATGTGAATGCAGTA
AATGGCTGGTTAAAACAATTATCACAAGCCGAGGTACAAAACTTTGTATCTACAGAAAGAGCAGTTTACGAAGTAGCCTC
AGGAGAAGAAGTAGTTGTAACAGCTGAAGATGTAATGGTTGAAAAAGTTGCAAAATCAGGCTTCTCTAATACGACTAACG
GACAATATACAGTAATGTTAGATACGAATGTAACGGAAGAATTATTACAAGAAGGAGTAGCACGTGAGTTTATTCGAGCC
GTTCAAGAATATCGTAAGCAGTTGAATTTACCAGTAAATTTACGAGTGGATGTTATTCTTGATACAGAGGAAGAACTACA
GCAAACGTTAACGAATCATAAAGAGTTGTTGAAAGAAAACTTACTCGTTAAACAATTTACATTTGGTCACTTAACGAATG
AAGACGATGAACTTTCTTTAGGTGAGACAAAAGTCCGCATTAAATTAAGTTCAGCTAATTAA

Upstream 100 bases:

>100_bases
GAGCTAATAGAATTAGGGTGGTATCGCGGGTAAACCCGTCCCTACTTCATAGGGACGGGTTTTTTGTGTGCTTTAAAATA
TTCAAAAGGAGTGATTGTAG

Downstream 100 bases:

>100_bases
AGGAAAGGAAGTTGGAATCATTCCAACTTCCTTTTTCTGTGCTAGAAATGTATCCGGCTATTTTACGCATAATCCATTCG
ATAGGGCCTCTAGCACATAT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase 2; IleRS 2 [H]

Number of amino acids: Translated: 1033; Mature: 1033

Protein sequence:

>1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMVGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIQKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFEVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYMPPFPMKEVTNGYHVIAADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTK
ETPEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKAPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVEKFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLINVYSFYVLYANLDEYNPHETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHVNLTGNSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKTFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQAEVQNFVSTERAVYEVASGEEVVVTAEDVMVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLKENLLVKQFTFGHLTNEDDELSLGETKVRIKLSSAN

Sequences:

>Translated_1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMVGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIQKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFEVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYMPPFPMKEVTNGYHVIAADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTK
ETPEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKAPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVEKFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLINVYSFYVLYANLDEYNPHETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHVNLTGNSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKTFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQAEVQNFVSTERAVYEVASGEEVVVTAEDVMVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLKENLLVKQFTFGHLTNEDDELSLGETKVRIKLSSAN
>Mature_1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMVGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIQKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFEVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYMPPFPMKEVTNGYHVIAADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTK
ETPEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKAPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVEKFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLINVYSFYVLYANLDEYNPHETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHVNLTGNSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKTFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQAEVQNFVSTERAVYEVASGEEVVVTAEDVMVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLKENLLVKQFTFGHLTNEDDELSLGETKVRIKLSSAN

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1034, Percent_Identity=36.2669245647969, Blast_Score=644, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1034, Percent_Identity=36.2669245647969, Blast_Score=644, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=781, Percent_Identity=30.6017925736236, Blast_Score=287, Evalue=4e-77,
Organism=Homo sapiens, GI268370293, Length=887, Percent_Identity=23.1116121758737, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI268370297, Length=885, Percent_Identity=23.0508474576271, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI268370295, Length=857, Percent_Identity=23.220536756126, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI5454158, Length=887, Percent_Identity=23.2243517474634, Blast_Score=152, Evalue=2e-36,
Organism=Escherichia coli, GI2367096, Length=786, Percent_Identity=29.5165394402036, Blast_Score=345, Evalue=9e-96,
Organism=Escherichia coli, GI1790708, Length=896, Percent_Identity=22.7678571428571, Blast_Score=183, Evalue=4e-47,
Organism=Escherichia coli, GI1786861, Length=376, Percent_Identity=22.3404255319149, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17541896, Length=988, Percent_Identity=38.0566801619433, Blast_Score=667, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=793, Percent_Identity=27.6166456494325, Blast_Score=257, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17510661, Length=858, Percent_Identity=24.1258741258741, Blast_Score=186, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI72001587, Length=874, Percent_Identity=23.1121281464531, Blast_Score=178, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1028, Percent_Identity=34.727626459144, Blast_Score=627, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6325217, Length=782, Percent_Identity=26.0869565217391, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321531, Length=843, Percent_Identity=23.6061684460261, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28574730, Length=1052, Percent_Identity=36.5019011406844, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1052, Percent_Identity=36.5019011406844, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1052, Percent_Identity=36.5019011406844, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=788, Percent_Identity=29.0609137055838, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI17864482, Length=859, Percent_Identity=23.0500582072177, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24653289, Length=859, Percent_Identity=23.0500582072177, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355675, Length=873, Percent_Identity=22.3367697594502, Blast_Score=147, Evalue=4e-35,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 118464; Mature: 118464

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMVGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIQKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFEVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYMPPFPMKEVTNGYHVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCHHHHCCCCCCCCCHHHHCCCEEEE
AADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEECCCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDSV
CHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHCCCCCE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCC
ETPEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
CCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKAPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVEKFGADALRWALLVDSAPWNAKRFSERTVLEAKSKFVDTLINVYSFYVLYANLDE
HHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPHETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHVNLTGNSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMNAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKTFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAVNGWLKQLSQAEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVASGEEVVVTAEDVMVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLKENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSSAN
CCEEEEEEEECCC
>Mature Secondary Structure
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMVGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIQKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFEVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYMPPFPMKEVTNGYHVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCHHHHCCCCCCCCCHHHHCCCEEEE
AADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEECCCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDSV
CHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHCCCCCE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCC
ETPEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
CCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKAPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVEKFGADALRWALLVDSAPWNAKRFSERTVLEAKSKFVDTLINVYSFYVLYANLDE
HHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPHETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHVNLTGNSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMNAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKTFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAVNGWLKQLSQAEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVASGEEVVVTAEDVMVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLKENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSSAN
CCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]