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The map label for this gene is moaE [H]

Identifier: 118477571

GI number: 118477571

Start: 2047735

End: 2048205

Strand: Direct

Name: moaE [H]

Synonym: BALH_1898

Alternate gene names: 118477571

Gene position: 2047735-2048205 (Clockwise)

Preceding gene: 118477570

Following gene: 118477572

Centisome position: 38.95

GC content: 40.34

Gene sequence:

>471_bases
ATGACACATACGTATTATGAAGTAATTGATACACCTATATCAATTGAAGAAGTGACAAACAAAGTAATTCGGCGTGAGTG
TGGTGCGATTACTACTTTTATTGGCACTGTTAGAGAATTTACGAAAGGCCGACGTACGCTTTATTTAGAGTATGTAGCTT
ATAAGACGATGGCGGAGAAACAGCTTGAGAGAATTGGTACCGAAGTAGGGGAGAAATGGCCTGGAACATATGTGGCAATT
ACACATCGCATTGGTATGTTACAAATTTCGGATCTTGCTGTTGTTGTCGCTGTTGCTACACCACATCGGAAAGCGGCCTA
TGAAGCAAATGAATATATTATGGAGCGTATAAAACAAATTGTTCCAATTTGGAAGAAAGAGTATTGGGAAGATGGTGAGT
CGTGGATAGGCGATCAGTTAGAGAAAACAGCATATGGTAATGGCGAGCCTGGAAAGGAGATGAGAATTTGA

Upstream 100 bases:

>100_bases
AATCAACCAGCGGAAGTGAATGGCCATGGAAAGAATCGCTTCGTTCATACAAATAATAGAAAAATAGGTTGCTAATTTAT
ACAAAGATAAGAGGTGCGAA

Downstream 100 bases:

>100_bases
TTGAAGTACTATTATTTGCACATTTACAAGAAGAAGTAAGTAAGCCAGCATTACACATAGATTGTGAAAATATTACAGTC
GCGAAGCTGAAGGAAGTTCT

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGMLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEYWEDGESWIGDQLEKTAYGNGEPGKEMRI

Sequences:

>Translated_156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGMLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEYWEDGESWIGDQLEKTAYGNGEPGKEMRI
>Mature_155_residues
THTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAIT
HRIGMLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEYWEDGESWIGDQLEKTAYGNGEPGKEMRI

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=39.3700787401575, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1787003, Length=137, Percent_Identity=37.2262773722628, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509279, Length=130, Percent_Identity=33.8461538461538, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356259, Length=131, Percent_Identity=33.587786259542, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18009; Mature: 17878

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGMLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEYWEDGESWIGDQLEKTAYGNGEPGKEMRI
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
THTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGMLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEHHCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEYWEDGESWIGDQLEKTAYGNGEPGKEMRI
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]