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The map label for this gene is moeA [H]

Identifier: 118477569

GI number: 118477569

Start: 2046401

End: 2047123

Strand: Direct

Name: moeA [H]

Synonym: BALH_1895

Alternate gene names: 118477569

Gene position: 2046401-2047123 (Clockwise)

Preceding gene: 118477568

Following gene: 118477570

Centisome position: 38.93

GC content: 40.53

Gene sequence:

>723_bases
ATGTTAGCAAAACGTATACCAATTCCAGTGGCGGAAGCAGTTGCACGAGTAATGAAATATGCTTATCAAGGTGAAACAGA
AGAGGTTTCTCTTATAGAAAGTTACGGAAGAACGCTTGGAGAAGATGTTATTGCAGATCATGATGTCCCGCATTTTGATC
GCTCTCCGTACGACGGATTTGCGATTAGAGCGGAAGATACAAAAGAAGCAAGTAGCAGTAATCCCATTCAGTTTGAAGTG
ATTGGTGAAATTGGAGCAGGGGTTGTTTTTACAGAAGAAGTGAAAGCATTTCAAGCTGTCCGTATTATGACAGGGGCCGC
AATTCCGAGAGGGTGTAATGCGGTTGTTATGTTAGAACTAACGGAAGGATTTGAAAGAAATGAAAGGACTTATATGACAT
TAAAACGCTGTTTTGCAGCTGGTGATAACATTTCTTTTAAAGGTGAAGATGTAAAACAAAATACTATCCTTGTGAAAGAA
GGGACTGTTATTAACCCGGGAGTTGCAGCACTTCTTGCTACGTTTGGTTATAGTTCCGTACACGTTGTAAAACGGCCGAT
TATTGGAATTGTAACGACGGGTAGTGAACTACTTGAAGTACATGAACAATTAAAACCAGGAAAGATTCGAAATAGTAACT
CCTATATGATAGCAGCGCAAATTGAACGAGCGGGCGGAGTTGTACGGTATTATGGACAATTCGTTGACGATTTTGAGACG
TGA

Upstream 100 bases:

>100_bases
TCATGGGACAAATGATGTGAAAATAGGAAAACGATTGTACGCAAAATATATAGGATGAACAGAAAGAAAGTTTCTCCTTA
TTAAAACGAGGTGAAAAAGA

Downstream 100 bases:

>100_bases
TATAACAATGTAAAAAAGGCGATAAAAGAAGTTGATATTTTAATTACGACTGGTGGCGTTTCAGTAGGAGACTATGACTA
TTTGCCTGCTATTTATGAGA

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLAKRIPIPVAEAVARVMKYAYQGETEEVSLIESYGRTLGEDVIADHDVPHFDRSPYDGFAIRAEDTKEASSSNPIQFEV
IGEIGAGVVFTEEVKAFQAVRIMTGAAIPRGCNAVVMLELTEGFERNERTYMTLKRCFAAGDNISFKGEDVKQNTILVKE
GTVINPGVAALLATFGYSSVHVVKRPIIGIVTTGSELLEVHEQLKPGKIRNSNSYMIAAQIERAGGVVRYYGQFVDDFET

Sequences:

>Translated_240_residues
MLAKRIPIPVAEAVARVMKYAYQGETEEVSLIESYGRTLGEDVIADHDVPHFDRSPYDGFAIRAEDTKEASSSNPIQFEV
IGEIGAGVVFTEEVKAFQAVRIMTGAAIPRGCNAVVMLELTEGFERNERTYMTLKRCFAAGDNISFKGEDVKQNTILVKE
GTVINPGVAALLATFGYSSVHVVKRPIIGIVTTGSELLEVHEQLKPGKIRNSNSYMIAAQIERAGGVVRYYGQFVDDFET
>Mature_240_residues
MLAKRIPIPVAEAVARVMKYAYQGETEEVSLIESYGRTLGEDVIADHDVPHFDRSPYDGFAIRAEDTKEASSSNPIQFEV
IGEIGAGVVFTEEVKAFQAVRIMTGAAIPRGCNAVVMLELTEGFERNERTYMTLKRCFAAGDNISFKGEDVKQNTILVKE
GTVINPGVAALLATFGYSSVHVVKRPIIGIVTTGSELLEVHEQLKPGKIRNSNSYMIAAQIERAGGVVRYYGQFVDDFET

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=207, Percent_Identity=36.7149758454106, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI10880983, Length=207, Percent_Identity=36.7149758454106, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1787049, Length=226, Percent_Identity=32.3008849557522, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147659, Length=210, Percent_Identity=30.952380952381, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562606, Length=162, Percent_Identity=30.2469135802469, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 26328; Mature: 26328

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKRIPIPVAEAVARVMKYAYQGETEEVSLIESYGRTLGEDVIADHDVPHFDRSPYDGF
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AIRAEDTKEASSSNPIQFEVIGEIGAGVVFTEEVKAFQAVRIMTGAAIPRGCNAVVMLEL
EEEECCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TEGFERNERTYMTLKRCFAAGDNISFKGEDVKQNTILVKEGTVINPGVAALLATFGYSSV
CCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCEECCHHHHHHHHHCCCHH
HVVKRPIIGIVTTGSELLEVHEQLKPGKIRNSNSYMIAAQIERAGGVVRYYGQFVDDFET
EEECCCEEEEEECCHHHHHHHHHCCCCCEECCCCEEEEEEEHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLAKRIPIPVAEAVARVMKYAYQGETEEVSLIESYGRTLGEDVIADHDVPHFDRSPYDGF
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AIRAEDTKEASSSNPIQFEVIGEIGAGVVFTEEVKAFQAVRIMTGAAIPRGCNAVVMLEL
EEEECCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TEGFERNERTYMTLKRCFAAGDNISFKGEDVKQNTILVKEGTVINPGVAALLATFGYSSV
CCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCEECCHHHHHHHHHCCCHH
HVVKRPIIGIVTTGSELLEVHEQLKPGKIRNSNSYMIAAQIERAGGVVRYYGQFVDDFET
EEECCCEEEEEECCHHHHHHHHHCCCCCEECCCCEEEEEEEHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]