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The map label for this gene is qorA [H]

Identifier: 118477552

GI number: 118477552

Start: 2025511

End: 2026497

Strand: Reverse

Name: qorA [H]

Synonym: BALH_1877

Alternate gene names: 118477552

Gene position: 2026497-2025511 (Counterclockwise)

Preceding gene: 118477555

Following gene: 118477551

Centisome position: 38.55

GC content: 39.21

Gene sequence:

>987_bases
ATGAAAGCTATCATTTTAACGTCGTTCGGTGGTCCTGAAGTGATGAAATATACAGATGTGGATATACCGGCTATTTCAGA
AGATCAAGTTTTAATTCGTGTTGTTGCTACGAGTGTAAATTTCGCTGATATTAAATCACGTTATGGCAAAAAAGGAAATA
AAGAGCTACCTTTTATTCTAGGGATAGATGCCGCTGGTATTGTAGAACGTGTCGGTTCTCATGCGAAAAATATTTATCCT
GGACAACGTGTCATTGCTTTCCCTCAAAATGGGTCTTACGCTGAATATGTTGTTGCAAATGAAAATCTTACTTTCGCATT
ACCTGATGAAGTCGATTTTCAAATTGCAGCAGCATGCCCTATCGTATCTTTCACAAGCTATAATTTACTCGCAAATGTAG
CAAGGATTCAACAAGGTGAATCTGTACTCATTCATGCGGCGGCTGGTGGAATTGGCACTACTGCTATTCAACTTGCAAAA
CTATTAGGGGCTGGAACAGTTATAGGTACTGTCGGAAGTGAAACAAAAAAAGAAATTGCTTTAGATGCCGGTGCTGATTA
TGTAATTGGTCATCAAGATGAAGATTTTGTAGAGAAAGTCAATGAGCTGACAAATGGTGAAGGGGTTGATGTAATTTTAG
ACTCTATTTCTGGAACGGTTTCGGAAAGAAGTTTAAAATGTCTTGCTTATTACGGCCGCCTCATTCATTTCGGTAATGCA
AGTGGTGAAATTGGCAATTTCCAAACGAAAGATTTACATGCAAGTTGCCGCTCTATACTCGGTTTTAGCTTTGGAACTAC
ACGAAAAAAACGTCCTGAACTACTCCAAGAAACTGCAAATGAAGTTTTCCGTTATTTGCGTGACGGACGTTTGCAAATCA
AGGCTACGAAATCTTTTCCACTTCAAGATGCAGGGAAAGCACATGAATGGGTCGAAAGTAGAAAAAGTACAGGGAAAGTA
ATACTAACTGTTCAGTCCTCCTCCTGA

Upstream 100 bases:

>100_bases
CATAAGCTTCACTTATAACCTTGCATAACAATTATATAATTTTCCAATTTCTAATGAACATTTAAAATGATCTATATAGT
CAAATTTAGGGGGATAAATA

Downstream 100 bases:

>100_bases
AATGAATACTTGAAACCGAGGTGTCATTCATGGGATCACGAATTATGCATGCTATTATCGCTAACGGTATTGCCGAAAAA
CTATGTATTCAAGATAAAAC

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAIILTSFGGPEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKELPFILGIDAAGIVERVGSHAKNIYP
GQRVIAFPQNGSYAEYVVANENLTFALPDEVDFQIAAACPIVSFTSYNLLANVARIQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSETKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS

Sequences:

>Translated_328_residues
MKAIILTSFGGPEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKELPFILGIDAAGIVERVGSHAKNIYP
GQRVIAFPQNGSYAEYVVANENLTFALPDEVDFQIAAACPIVSFTSYNLLANVARIQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSETKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS
>Mature_328_residues
MKAIILTSFGGPEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKELPFILGIDAAGIVERVGSHAKNIYP
GQRVIAFPQNGSYAEYVVANENLTFALPDEVDFQIAAACPIVSFTSYNLLANVARIQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSETKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=33.7423312883436, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=33.7423312883436, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI22538446, Length=334, Percent_Identity=31.1377245508982, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI22538444, Length=334, Percent_Identity=31.1377245508982, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=30.9815950920245, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=27.7456647398844, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI18379349, Length=341, Percent_Identity=26.6862170087977, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI47519420, Length=243, Percent_Identity=30.0411522633745, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI67078404, Length=339, Percent_Identity=25.9587020648968, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=30.1020408163265, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41872631, Length=236, Percent_Identity=30.0847457627119, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI28557745, Length=225, Percent_Identity=30.6666666666667, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI67078406, Length=305, Percent_Identity=26.8852459016393, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=37.4613003095975, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI226510941, Length=331, Percent_Identity=22.3564954682779, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=30.2752293577982, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71987554, Length=369, Percent_Identity=25.2032520325203, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=335, Percent_Identity=25.9701492537313, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=306, Percent_Identity=26.797385620915, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=331, Percent_Identity=33.2326283987915, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319945, Length=266, Percent_Identity=27.4436090225564, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323493, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=271, Percent_Identity=25.0922509225092, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=258, Percent_Identity=25.1937984496124, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324195, Length=266, Percent_Identity=25.187969924812, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581345, Length=303, Percent_Identity=28.7128712871287, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19920632, Length=298, Percent_Identity=27.5167785234899, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330659, Length=298, Percent_Identity=27.5167785234899, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35346; Mature: 35346

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIILTSFGGPEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKELPFIL
CCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
GIDAAGIVERVGSHAKNIYPGQRVIAFPQNGSYAEYVVANENLTFALPDEVDFQIAAACP
ECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCEEEECCCCCCEEEEECCC
IVSFTSYNLLANVARIQQGESVLIHAAAGGIGTTAIQLAKLLGAGTVIGTVGSETKKEIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHHEE
LDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
EECCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVILTVQSSS
CCCCCHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure
MKAIILTSFGGPEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKELPFIL
CCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
GIDAAGIVERVGSHAKNIYPGQRVIAFPQNGSYAEYVVANENLTFALPDEVDFQIAAACP
ECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCEEEECCCCCCEEEEECCC
IVSFTSYNLLANVARIQQGESVLIHAAAGGIGTTAIQLAKLLGAGTVIGTVGSETKKEIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCHHHEE
LDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
EECCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVILTVQSSS
CCCCCHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]