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The map label for this gene is yclK [H]

Identifier: 118477018

GI number: 118477018

Start: 1461778

End: 1463589

Strand: Reverse

Name: yclK [H]

Synonym: BALH_1317

Alternate gene names: 118477018

Gene position: 1463589-1461778 (Counterclockwise)

Preceding gene: 118477019

Following gene: 118477017

Centisome position: 27.84

GC content: 31.68

Gene sequence:

>1812_bases
GTGAAAAACAGAAGTATCGTCTTTAAACTATTTCTATTAACATCAACATTATTTACAATCATATTCCTTCTTTTTTTCCT
AGGGCAATCTCTATTTTTAGAAAAATTTTATATCAATAAAAAAGTAAAAACCGTTCAAACTGCTTTTGAAAAATTCGTAG
CTAATTATGAAAAAAGCGAAAAAGATCCTGAGGAAGTTAGAAAACTAAAACAAGAATTTCATGATAAAACAAATGCTGAC
ATGCAATTTTTAAATACGAATGGCATTATTAAAAGCGACAACAATTACTACATTGATGTATTTAATCCTAAAAATCATGA
AACATATTCCATTCCGCTTAATAATCTTTTAACACCCGAAGAATATAAGAAATTCGAAAACTTAGGATTGAAAAAAGACG
ATGTGATAAACGTCGTAGGTTTGCTACAAAACAAAACAATAACACCAATAAAATTGACAACAAATTATAATCGTTGGCAA
AACGAATATACCAATTCAGATTTTTCATCTATTAATGGTAATCCTTCTAAAAATAGACTTACAAACCGATACAAAACTGT
TACTCAAATTGAGTTTACTGGTACTATATCTAAGTTACAGCTTCCATCGAAAGCCGAGGTTCGTCTTGCAAATGATATTG
AAACATTACAAGCCGTTCAATATTTTGCAGAGCTTATTAGAAATGGCACTGCTAACTCGCAGCAATTAAACACTTATATA
ATAGATAGCGGGGAGAATATAAAGAATAGTATCTTTGTAAAACCTATTATAGAAAATGGAGAGATTACAGAATATGCTTT
TGCGATAGCATCCTTGCAACCTGTTAATGAAGCGATGCTCGTTTTAAAAGATTATTATGTCTATGCCTTAATCATCGTAT
TTCTCGTAATTATTTTGTTATCCTTCTACTACTCAAAAATCATTGTGAAACCATTAATTAAAATCAATCGCGTTACAAAG
AAAATGGCCAACTTTGATTTTAGCGAAAAATTACCTGTAACAGCAGACGATGAAATTGGCGGACTTTCTGGTAGTATTAA
TACGTTATCTGTAAATTTAAAAGACCGAATCGATCGATTAAATGTTGCAAACACAAAATTACAACAAGATATTGAACGTG
AACGTCAATTAGAGAAAACGCGAAAAGAATTCATTTCTGGTGTATCACACGAATTAAAAACACCGCTCAGTGTAATTAGA
AGTTTCGCAGAAGGAATTAAAGATGGTGTTAGTAAAGATACGACGTATTACACAGATGTTATTTTAGAAGAAACAGAAAA
TATGAACAGACTTATTGTTGAAATGTTAGAATTAGCAAAATTAGAATCAGGTACGTACAAACTAGATATGACGACATTCT
CAATCGGTGAATTAATTCAACAAGTCTATACAAAATTATTATTTAGCATGGAAGAAAAGCATTTACAAGTGAACATAGAT
GTAGACTCTTCTATAGTTGTGAAAGCGAATCGTAGTCGTATTGAGCAAGTGGTTGTGAACTTACTTAGCAATGCAATTCG
CTATACGCCAGATGGAGAAAAAATACAAGTCTCCGTTATAGCAATGGAAGATACAGTAAAAGTCGAAATCGAAAACACAG
GAAATCCTATCCCAGAAGAAAGTCTTGAAAAAATTTGGGATCGCTTCTACCGTTTAGATGCATCTCGTAGCCGTCATACT
GGTGGTACTGGTCTCGGTTTATCTATTGTAAAAAACATTTTAGATCTCCACCATGCTGAGTACGGTGTATATAACACGAC
TAATAGCGTTGTATTCTACTTTAATTTACAAAAAGTAAAAGAAGTCAAATAA

Upstream 100 bases:

>100_bases
AAAACTACTTTCGGAAGAGACAGATTTTCTCCTCTACTTTTTTGTAACGTTTGTTATAATAAAGTAATCATTTACAGTAT
TTCTCACAAGAGGTGACGCA

Downstream 100 bases:

>100_bases
TTTGTCTTAATTTCACTAGGAGTTCACATGAAATTCACACTCTCCCTTTATAGTTAGAAACAAGTTAATCCTTTCCTTTA
CACATATAAAAGAGGAGAGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKDPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIDVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNKTITPIKLTTNYNRWQ
NEYTNSDFSSINGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIENGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDSSIVVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIAMEDTVKVEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Sequences:

>Translated_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKDPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIDVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNKTITPIKLTTNYNRWQ
NEYTNSDFSSINGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIENGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDSSIVVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIAMEDTVKVEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK
>Mature_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKDPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIDVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNKTITPIKLTTNYNRWQ
NEYTNSDFSSINGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIENGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDSSIVVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIAMEDTVKVEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=298, Percent_Identity=27.5167785234899, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=29.0178571428571, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=27.4131274131274, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786783, Length=352, Percent_Identity=26.4204545454545, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=29.4372294372294, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788279, Length=376, Percent_Identity=26.8617021276596, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87082128, Length=325, Percent_Identity=22.4615384615385, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=27.3542600896861, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788713, Length=215, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=29.1479820627803, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=308, Percent_Identity=25, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.25, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=315, Percent_Identity=23.4920634920635, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=28.8288288288288, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=275, Percent_Identity=26.9090909090909, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=24.5791245791246, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789403, Length=303, Percent_Identity=23.7623762376238, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69200; Mature: 69200

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDPEEVRKLKQEFHDKTNADMQFLNTNGIIKSDNNYYIDVFNPKNHETYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCCEEECCCCCCCCHH
EYKKFENLGLKKDDVINVVGLLQNKTITPIKLTTNYNRWQNEYTNSDFSSINGNPSKNRL
HHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHH
TNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
HHHHHEEEEEEEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDSGENIKNSIFVKPIIENGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
EECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VDSSIVVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIAMEDTVKVEIENTGNPIPEE
CCCEEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHH
EVK
CCC
>Mature Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDPEEVRKLKQEFHDKTNADMQFLNTNGIIKSDNNYYIDVFNPKNHETYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCCEEECCCCCCCCHH
EYKKFENLGLKKDDVINVVGLLQNKTITPIKLTTNYNRWQNEYTNSDFSSINGNPSKNRL
HHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHH
TNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
HHHHHEEEEEEEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDSGENIKNSIFVKPIIENGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
EECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VDSSIVVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIAMEDTVKVEIENTGNPIPEE
CCCEEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHH
EVK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]