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The map label for this gene is gltT [H]

Identifier: 118476950

GI number: 118476950

Start: 1392665

End: 1393900

Strand: Reverse

Name: gltT [H]

Synonym: BALH_1243

Alternate gene names: 118476950

Gene position: 1393900-1392665 (Counterclockwise)

Preceding gene: 118476952

Following gene: 118476948

Centisome position: 26.51

GC content: 39.0

Gene sequence:

>1236_bases
TTGAAACAAACAAAAGCAATCTTAATTGCATTATTTCTCGGTTTAGTTGTCGGACTCACTTTAAATTTAGCTGCTCCATC
CATTTTTGATCCATTAAATCAATATGTGTTCAATCCACTTGGTCAATTGTTTATTCGACTCATTAAAATGCTAGTTGTTC
CTGTCGTGTTTATTTCTATCGTGCTTGGAGCTGCCGGCCTTGGAGATCCGAAGCAACTTGGAAGAATCGGTTTAAAATCA
ATTTCATTCTTCCTCGTAACGACAGCTGTTGCCATCTCTATTGCTGTTACATTTGCACTTATTATAAAACCAGGATCTGG
CGGTAACTTTAAAACCGAAGGGCTTAAATATGAGGGGGCAAAAACTGAAACATCTTTCGTTGATACATTGCTGAATATCG
TACCAGATAATCCAGCAAAAGCGATGGCTGATGGAAACATGTTACAAATTATTGCCTTCGCCGTATTAATTGGACTCGGT
ATAGCTATTTTAGGAAAACGAGTTCAAGGTATCCATTCATTACTTGAACAGGGCAACGAATTAATGATGTATCTCGTTAA
TCTCGTTATGAAATTGGCTCCAATCGGAACATTTGGCTTGCTCGCTTCATCCGTTGGTAAAATGGGTCTTGCAGGCGTCG
CTGCGATGTTCAAGTATATGATTGTCGTTATGTTGGTACTCATTATTCACGGGGTCTTCGTATATGGCGGCTTATTAAAA
GTATTAGCAAAAGAAAGTATTGTCCGTTTCTTTAAACATTTCGGACCGGTAATGGCAATTGGGTTTAGTACATCGAGCTC
TAATGCATCTCTTCCATTCGCAATGAAAACTGCACAAGAGAAGCTTGGAGTTCCAAAAGCAATTAGCTCTTTTGTACAAC
CACTAGGTGCAACAATTAATATGGATGGTACTGCTATTATGCAAGGTGTAGCAACTGTATTTATCGCTCAAGTGTACGGC
GTTGAACTTACAGTGACACAATTAGCTGTCGTCGTATTAACTGCTGTACTAGCTAGTATCGGCACTGCTGGTGTACCAGG
TGTTGGACTTGTAATGCTTACGATGGTTTTAAATCAAGTAAATCTACCGGTAGAAGGTATTGCCTTAATTATCGGAATTG
ACCGCATTCTAGATATGTCAAGAACAGCTGTAAATATTTCTGGTGATGCAATTTGCGCAATGATTGTCGCAAAATCAGAA
GAAAAATATAATACGGATCAATCTGCCGCATCTTAA

Upstream 100 bases:

>100_bases
TATTTTTATACAAAATATTCAGAAAACATTGTCAAAATAGGGATTTTTTCGGTACAATTAATGTAGAAAATTATTTCACA
AAAAATAAGGGGGGATTTTA

Downstream 100 bases:

>100_bases
ATCAAAAAAGGAGTGAAATGATTCACTCCTTTTTTGATTTACTTCCCTTTTTCGAACGATATTCTTTTCCTTTGTTATCA
TCACCAGTTTCAAATTCTGC

Product: proton/sodium-glutamate symport protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFDPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIKPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTVTQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS

Sequences:

>Translated_411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFDPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIKPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTVTQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS
>Mature_411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFDPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIKPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTVTQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=403, Percent_Identity=33.4987593052109, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI169790839, Length=455, Percent_Identity=30.989010989011, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI5032093, Length=397, Percent_Identity=34.2569269521411, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI40254478, Length=448, Percent_Identity=31.0267857142857, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI66773030, Length=450, Percent_Identity=30, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI223468564, Length=250, Percent_Identity=37.2, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI223468566, Length=250, Percent_Identity=37.2, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI4827012, Length=286, Percent_Identity=34.965034965035, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI194239697, Length=264, Percent_Identity=36.7424242424242, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI262359914, Length=377, Percent_Identity=27.8514588859416, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI301601644, Length=172, Percent_Identity=40.6976744186046, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1790514, Length=416, Percent_Identity=37.0192307692308, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1789947, Length=410, Percent_Identity=31.219512195122, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788024, Length=393, Percent_Identity=30.2798982188295, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789473, Length=286, Percent_Identity=27.6223776223776, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71983099, Length=408, Percent_Identity=32.843137254902, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71983106, Length=408, Percent_Identity=32.843137254902, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71996953, Length=464, Percent_Identity=30.8189655172414, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17537407, Length=433, Percent_Identity=31.6397228637413, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI193206505, Length=445, Percent_Identity=29.2134831460674, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193206654, Length=396, Percent_Identity=30.3030303030303, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17541374, Length=398, Percent_Identity=27.1356783919598, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24583025, Length=429, Percent_Identity=28.9044289044289, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI17137668, Length=429, Percent_Identity=28.9044289044289, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24583023, Length=429, Percent_Identity=28.9044289044289, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360483, Length=464, Percent_Identity=28.0172413793103, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17137666, Length=464, Percent_Identity=28.0172413793103, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281360481, Length=455, Percent_Identity=27.9120879120879, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43117; Mature: 43117

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTKAILIALFLGLVVGLTLNLAAPSIFDPLNQYVFNPLGQLFIRLIKMLVVPVVFISI
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGAAGLGDPKQLGRIGLKSISFFLVTTAVAISIAVTFALIIKPGSGGNFKTEGLKYEGA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCC
KTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLGIAILGKRVQGIHSLLEQGNE
CCHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATIN
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEC
MDGTAIMQGVATVFIAQVYGVELTVTQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSEEKYNTDQSAAS
CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHCCCCCCCCC
>Mature Secondary Structure
MKQTKAILIALFLGLVVGLTLNLAAPSIFDPLNQYVFNPLGQLFIRLIKMLVVPVVFISI
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGAAGLGDPKQLGRIGLKSISFFLVTTAVAISIAVTFALIIKPGSGGNFKTEGLKYEGA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCC
KTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLGIAILGKRVQGIHSLLEQGNE
CCHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATIN
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEC
MDGTAIMQGVATVFIAQVYGVELTVTQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQV
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSEEKYNTDQSAAS
CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]