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The map label for this gene is ycgO [H]

Identifier: 118476807

GI number: 118476807

Start: 1239972

End: 1241450

Strand: Reverse

Name: ycgO [H]

Synonym: BALH_1094

Alternate gene names: 118476807

Gene position: 1241450-1239972 (Counterclockwise)

Preceding gene: 118476817

Following gene: 118476806

Centisome position: 23.61

GC content: 37.25

Gene sequence:

>1479_bases
ATGAGTACGCAGATGTTAACTTTAACTTCTATCTCTATTTACATGCTCGGGATGTTAGTAATTGGCTATTTCGCCTATAA
ACGAACGTCCAACTTAACAGATTATATGCTTGGCGGGCGTACACTAGGCCCCGCAGTAACAGCATTAAGTGCTGGAGCAT
CCGATATGAGTGGTTGGCTTTTAATGGGCTTACCCGGTGCAATGTTTAGCGTTGGATTAAGTAGTAGTTGGATTGCGATC
GGCCTAACACTAGGCGCATACGCAAACTGGCTATATGTTGCTCCTCGCTTACGTACCTACTCTGAAATTGCAAACAACTC
TATTACTATCCCAGAATTTTTGGAACATCGCTTCCAAGACAAATCCCATATGCTACGCTTAGTATCCGGACTTGTTATTA
TGATTTTCTTTACTTTTTATGTAGCTTCAGGATTAGTTTCAGGCGCTGTATTATTTGAAAATTCATTTGGTATGAACTAC
CATGTTGGATTATTCATTGTTGCAGGCGTTGTTGTAGCTTACACGTTATTTGGTGGTTTCTTAGCAGTAAGTTGGACAGA
CTTCGTGCAAGGAATCATTATGGTAATTGCTCTTATTCTTGTTCCTACTGTTACAATTATGAATGTAAATGGGCTTGGTC
CAGCATTTAGCACAATTAAATCAATTGATCCAACATTATTAGACATTTTTAAAGGCACTTCTGTATTAGGTATTATTTCA
TTATTCGCATGGGGCCTTGGTTATGTTGGACAACCACATATTATCGTACGCTTTATGGCGATTTCTTCTGTAAAAGAAAT
TAAAAGTGCAAGACGAATTGGTATGAGCTGGATGATTTTCTCTGTTGTTGGAGCTATGTTTACTGGTCTTATCGGTATTG
CATACTACTCAGACAAAGGATTAAAGCTATCCAATCCAGAGACAATTTTCCTTGAACTAGGAAAAATTTTATTCCACCCG
CTTATTACTGGATTTTTATTAGCCGCTATTTTAGCAGCAATTATGAGTACAATCTCATCTCAGTTACTCGTTACTTCTAG
TGCCATAACTGAAGACTTATATCGTACTTTCTTTAAACGTTCTGCTTCTGATAAAGAGCTTGTATTTGTCGGCCGTATGG
CTGTACTTGTTATTGCATTAGTTGGATGTGCATTAGCGTTTAAACAAAATGATACGATTTTAGCTCTTGTTGGATACGCT
TGGGCTGGATTTGGCTCTTCATTCGGACCTGCTATTTTATTAAGCTTATATTGGAAACGTATGACGAAGTGGGGCGCACT
TGCTGGTATGATTTCTGGTGCGGCTACAGTCATTATTTGGACTCAATTCAAATTCTTAAAAGAATTCTTATATGAAATGA
TTCCTGGTTTCACTATTAGTTTACTAGTAATCATAATTGTTAGTTTACTAACACAGCCTTCAAAAGAAATTGAAAAGCAA
TTTGAGGATTTCGAAAAACAACATAGTGATAATCTATAA

Upstream 100 bases:

>100_bases
CTGAAAATTCATATTTCTATATGGATTTTTCAGAATAATCATGATAGATTATAAATATGCATAACGCATCAAAAGACATG
ACAAAAGGAAGGGGAACTAC

Downstream 100 bases:

>100_bases
AGGAAAAGCTCTGCTGTTATGATAGCAGAGCTTTCTTTTTATCCCGCTATTTGTTGGCAATAAGACTCACACCTCAAAAT
TCGGCGAATACGAAGGAGCT

Product: osmoregulated proline transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSTQMLTLTSISIYMLGMLVIGYFAYKRTSNLTDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFSVGLSSSWIAI
GLTLGAYANWLYVAPRLRTYSEIANNSITIPEFLEHRFQDKSHMLRLVSGLVIMIFFTFYVASGLVSGAVLFENSFGMNY
HVGLFIVAGVVVAYTLFGGFLAVSWTDFVQGIIMVIALILVPTVTIMNVNGLGPAFSTIKSIDPTLLDIFKGTSVLGIIS
LFAWGLGYVGQPHIIVRFMAISSVKEIKSARRIGMSWMIFSVVGAMFTGLIGIAYYSDKGLKLSNPETIFLELGKILFHP
LITGFLLAAILAAIMSTISSQLLVTSSAITEDLYRTFFKRSASDKELVFVGRMAVLVIALVGCALAFKQNDTILALVGYA
WAGFGSSFGPAILLSLYWKRMTKWGALAGMISGAATVIIWTQFKFLKEFLYEMIPGFTISLLVIIIVSLLTQPSKEIEKQ
FEDFEKQHSDNL

Sequences:

>Translated_492_residues
MSTQMLTLTSISIYMLGMLVIGYFAYKRTSNLTDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFSVGLSSSWIAI
GLTLGAYANWLYVAPRLRTYSEIANNSITIPEFLEHRFQDKSHMLRLVSGLVIMIFFTFYVASGLVSGAVLFENSFGMNY
HVGLFIVAGVVVAYTLFGGFLAVSWTDFVQGIIMVIALILVPTVTIMNVNGLGPAFSTIKSIDPTLLDIFKGTSVLGIIS
LFAWGLGYVGQPHIIVRFMAISSVKEIKSARRIGMSWMIFSVVGAMFTGLIGIAYYSDKGLKLSNPETIFLELGKILFHP
LITGFLLAAILAAIMSTISSQLLVTSSAITEDLYRTFFKRSASDKELVFVGRMAVLVIALVGCALAFKQNDTILALVGYA
WAGFGSSFGPAILLSLYWKRMTKWGALAGMISGAATVIIWTQFKFLKEFLYEMIPGFTISLLVIIIVSLLTQPSKEIEKQ
FEDFEKQHSDNL
>Mature_491_residues
STQMLTLTSISIYMLGMLVIGYFAYKRTSNLTDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFSVGLSSSWIAIG
LTLGAYANWLYVAPRLRTYSEIANNSITIPEFLEHRFQDKSHMLRLVSGLVIMIFFTFYVASGLVSGAVLFENSFGMNYH
VGLFIVAGVVVAYTLFGGFLAVSWTDFVQGIIMVIALILVPTVTIMNVNGLGPAFSTIKSIDPTLLDIFKGTSVLGIISL
FAWGLGYVGQPHIIVRFMAISSVKEIKSARRIGMSWMIFSVVGAMFTGLIGIAYYSDKGLKLSNPETIFLELGKILFHPL
ITGFLLAAILAAIMSTISSQLLVTSSAITEDLYRTFFKRSASDKELVFVGRMAVLVIALVGCALAFKQNDTILALVGYAW
AGFGSSFGPAILLSLYWKRMTKWGALAGMISGAATVIIWTQFKFLKEFLYEMIPGFTISLLVIIIVSLLTQPSKEIEKQF
EDFEKQHSDNL

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=491, Percent_Identity=54.786150712831, Blast_Score=543, Evalue=1e-154,
Organism=Homo sapiens, GI110835708, Length=553, Percent_Identity=23.869801084991, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI206597483, Length=438, Percent_Identity=24.8858447488584, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI206597487, Length=438, Percent_Identity=24.8858447488584, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507031, Length=555, Percent_Identity=21.981981981982, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI109659836, Length=442, Percent_Identity=22.3981900452489, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI14140236, Length=551, Percent_Identity=22.6860254083485, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI109659839, Length=458, Percent_Identity=22.0524017467249, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4507035, Length=364, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI11141885, Length=451, Percent_Identity=24.390243902439, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4507033, Length=410, Percent_Identity=24.8780487804878, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787251, Length=493, Percent_Identity=54.5638945233266, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI87082237, Length=442, Percent_Identity=28.2805429864253, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1790503, Length=501, Percent_Identity=25.748502994012, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1790113, Length=494, Percent_Identity=23.2793522267206, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533094, Length=387, Percent_Identity=24.2894056847545, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17539284, Length=474, Percent_Identity=22.5738396624473, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24645928, Length=383, Percent_Identity=26.8929503916449, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221459584, Length=373, Percent_Identity=22.7882037533512, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221459588, Length=398, Percent_Identity=25.1256281407035, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221459586, Length=385, Percent_Identity=25.4545454545455, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640370, Length=368, Percent_Identity=24.1847826086957, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650192, Length=379, Percent_Identity=22.6912928759894, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221459582, Length=372, Percent_Identity=24.4623655913978, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651739, Length=349, Percent_Identity=25.214899713467, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573698, Length=408, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362918, Length=289, Percent_Identity=25.9515570934256, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651741, Length=183, Percent_Identity=31.6939890710383, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19920916, Length=402, Percent_Identity=24.6268656716418, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53717; Mature: 53586

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQMLTLTSISIYMLGMLVIGYFAYKRTSNLTDYMLGGRTLGPAVTALSAGASDMSGWL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEE
LMGLPGAMFSVGLSSSWIAIGLTLGAYANWLYVAPRLRTYSEIANNSITIPEFLEHRFQD
EECCCHHHHHHCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCHHHHHHHHHCC
KSHMLRLVSGLVIMIFFTFYVASGLVSGAVLFENSFGMNYHVGLFIVAGVVVAYTLFGGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LAVSWTDFVQGIIMVIALILVPTVTIMNVNGLGPAFSTIKSIDPTLLDIFKGTSVLGIIS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHH
LFAWGLGYVGQPHIIVRFMAISSVKEIKSARRIGMSWMIFSVVGAMFTGLIGIAYYSDKG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
LKLSNPETIFLELGKILFHPLITGFLLAAILAAIMSTISSQLLVTSSAITEDLYRTFFKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SASDKELVFVGRMAVLVIALVGCALAFKQNDTILALVGYAWAGFGSSFGPAILLSLYWKR
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCHHHHHHHHHHHH
MTKWGALAGMISGAATVIIWTQFKFLKEFLYEMIPGFTISLLVIIIVSLLTQPSKEIEKQ
HHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
FEDFEKQHSDNL
HHHHHHHHCCCC
>Mature Secondary Structure 
STQMLTLTSISIYMLGMLVIGYFAYKRTSNLTDYMLGGRTLGPAVTALSAGASDMSGWL
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEE
LMGLPGAMFSVGLSSSWIAIGLTLGAYANWLYVAPRLRTYSEIANNSITIPEFLEHRFQD
EECCCHHHHHHCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCHHHHHHHHHCC
KSHMLRLVSGLVIMIFFTFYVASGLVSGAVLFENSFGMNYHVGLFIVAGVVVAYTLFGGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LAVSWTDFVQGIIMVIALILVPTVTIMNVNGLGPAFSTIKSIDPTLLDIFKGTSVLGIIS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHH
LFAWGLGYVGQPHIIVRFMAISSVKEIKSARRIGMSWMIFSVVGAMFTGLIGIAYYSDKG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
LKLSNPETIFLELGKILFHPLITGFLLAAILAAIMSTISSQLLVTSSAITEDLYRTFFKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SASDKELVFVGRMAVLVIALVGCALAFKQNDTILALVGYAWAGFGSSFGPAILLSLYWKR
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCHHHHHHHHHHHH
MTKWGALAGMISGAATVIIWTQFKFLKEFLYEMIPGFTISLLVIIIVSLLTQPSKEIEKQ
HHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
FEDFEKQHSDNL
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]