Click here to switch to the map view.

The map label for this gene is scrK [H]

Identifier: 118476425

GI number: 118476425

Start: 798307

End: 799248

Strand: Reverse

Name: scrK [H]

Synonym: BALH_0688

Alternate gene names: 118476425

Gene position: 799248-798307 (Counterclockwise)

Preceding gene: 118476426

Following gene: 118476422

Centisome position: 15.2

GC content: 35.88

Gene sequence:

>942_bases
ATGAGAAATGTCTTTTGTATCGGTGAACTATTAATTGATTTCGTTTGCCGAAATACCAATGTTTCTTTAGTAAACGGTTC
AAATTTCGAAAAAAAAGCTGGTGGAGCACCCGCTAACGTTGCTGCTGCTATTACAAAATTAGGTGGACACGCTACATTTA
TGGGACAAGTAGGAAACGATCCATTTGGTGAATTTCTTGAACAAACTTTACAACATGCACATGTGGACACTTCCATGCTC
ATCAAGGATAAACAAACCACACTTGCATTCGTATCTATCGATCAAAATGGTGAGCGTGATTTTACCTTTATGCGTGGCGC
AGACGGCGAATATCATTTCAATAGCATTGATTTATCAAAAATAAAAACGAATGATTTAATCCACTTTGGTTCAGCGACAG
CTTTATTGTCCAGCCCGTTAAAAGACACATATTTTCAACTTCTACAATATGCAAGAGAAAGTGGCCAGTTTATTTCTTTT
GATCCAAATTACCGAAATGCGCTCATTACAAATACCGAACAATTTATTCAAGATTGCTTAACTTTTATAAAACATGCTCA
TTTTGTAAAAGTAAGTCAAGAAGAAGCGATTATGCTTTCTAAAGAGAGTGATTTACAACAATCTGCACTCAAATTATTAA
ATCATGGTGCGAAAGCCGTAGCTATTACACTCGGAAAAGACGGTACTCTTCTTGCAACAAAGGATAAGCAAACTATTGTA
CCTTCTATCTCTATTCAACAAGTTGATACTACTGGCGCTGGTGATGCTTTCGTTGGAGCAATGTTATACCAAATTGCTAA
AAGTGAACAAATATTTCTTCATAATTTTGAAGATTTAACAACGTTCATCTCCTTTGCAAATAAAGTAGGTGCTCTCACAT
GTACAAATTACGGAGCCATTTCCTCTCTTCCATCATTAACAGATGTAAAAGCATACGAGTAA

Upstream 100 bases:

>100_bases
GAGTTTTTCCTCGAAAAGACTTGAAACATCATATAGCAATCTTTTCAGATGCAAAACTAAACTTTATCATTACACAACAT
AAGCTGAAAAGAGGGATTGT

Downstream 100 bases:

>100_bases
TCGTATGCTTTTTACATTCCCCTCCAAAAATCATGCATAATAAAAAAGTACAAAATAACGAGAACTGCCGTCCCGCATAA
GGTAATACGCCGATATATAC

Product: fructokinase

Products: ADP; D-fructose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQYARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQIFLHNFEDLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE

Sequences:

>Translated_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQYARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQIFLHNFEDLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE
>Mature_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQHAHVDTSML
IKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSKIKTNDLIHFGSATALLSSPLKDTYFQLLQYARESGQFISF
DPNYRNALITNTEQFIQDCLTFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQIFLHNFEDLTTFISFANKVGALTCTNYGAISSLPSLTDVKAYE

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=285, Percent_Identity=25.6140350877193, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081971, Length=312, Percent_Identity=23.7179487179487, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082281, Length=280, Percent_Identity=23.9285714285714, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790193, Length=244, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=297, Percent_Identity=26.9360269360269, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20128807, Length=323, Percent_Identity=25.3869969040248, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=26, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.4

Molecular weight: Translated: 34258; Mature: 34258

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQHAHVDTSMLIKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSK
HHHHHHHHHHHHHCCCHHEEEECCCEEEEEEEECCCCCCCEEEEECCCCCEEECCEEHHH
IKTNDLIHFGSATALLSSPLKDTYFQLLQYARESGQFISFDPNYRNALITNTEQFIQDCL
CCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHH
TFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
HHHHHHHEEEECCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEC
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQIFLHNFEDLTTFISFANKVGALTCTNYGAI
CCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCEEEECCCCCH
SSLPSLTDVKAYE
HCCCCCCCCCCCC
>Mature Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSNFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQHAHVDTSMLIKDKQTTLAFVSIDQNGERDFTFMRGADGEYHFNSIDLSK
HHHHHHHHHHHHHCCCHHEEEECCCEEEEEEEECCCCCCCEEEEECCCCCEEECCEEHHH
IKTNDLIHFGSATALLSSPLKDTYFQLLQYARESGQFISFDPNYRNALITNTEQFIQDCL
CCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHH
TFIKHAHFVKVSQEEAIMLSKESDLQQSALKLLNHGAKAVAITLGKDGTLLATKDKQTIV
HHHHHHHEEEECCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEC
PSISIQQVDTTGAGDAFVGAMLYQIAKSEQIFLHNFEDLTTFISFANKVGALTCTNYGAI
CCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCEEEECCCCCH
SSLPSLTDVKAYE
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-fructose

Specific reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]