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The map label for this gene is cpsA [H]

Identifier: 118476383

GI number: 118476383

Start: 744905

End: 746104

Strand: Direct

Name: cpsA [H]

Synonym: BALH_0641

Alternate gene names: 118476383

Gene position: 744905-746104 (Clockwise)

Preceding gene: 118476382

Following gene: 118476384

Centisome position: 14.17

GC content: 39.83

Gene sequence:

>1200_bases
TTGGTGAAGAAGGGGAGAAGAAAAATGGATGTTGCAAAAGAACTTGTTTTGTCAAAGGATCAGTTGATTGAGTGGAGAAG
GCATTTTCATAAGTATCCAGAGTTATCTTTTCAAGAAGAAAAAACATCACAGTTTGTATTCGACATACTTCGGAAAATCC
CACATCTAGAAGTGTCAAGACCTACTAAATATAGTGTAATGGCAAGGTTGATTGGAAAGCAGTCTGGTAAAACTATTGCG
GTTCGTGCTGACATGGATGCTCTTCCTATTCATGAAGAAAATGAGTTTGACTTTATTTCTGCATATCCAGGTGTAATGCA
TGCATGTGGCCATGATGGACATATAGCGATATTACTTGGAGTCGTACATAAGTTAGTAGAAGCAAGAGAGAAGATTAAAG
GGGAGGTTCGTTTTCTATTCCAACATGCTGAAGAAAACTTTCCTGGCGGTGCAGAGGAAATGGTCGCGGCAGGTGTAATG
GAAGGGGTCGATTATATTATTGGTGCTCACCTTTGGGCATCGTTACACGTTGGAAAAGTAGGTGTAATTTATGGTCCTGC
AATGGCTGCTCCAGATGTTTTTAAAATTACGATAGAAGGAAAAGGTGGACATGCTGGAATCCCTCATGAAACGGTTGATA
GTATTGCTATCGGTACACAAGTGGTTTCGCAACTTCAGCAAATTGTATCTCGCCTTACGAATCCGTTAGATTCCCTTGTA
GTATCTGTTACGCAATTTCACGCTGGGACAACCCATAATGTGATTCCAGAACAAGCGGAGATTGAAGGGACGGTGCGGAG
TTTAAGACATGAGTTGCGAGAAGAAACAGAGAAAAGGATTGAACAGATCGTAAAGCACGTGACAGAAGCTTACGGAGCGA
AATATACGTTTTCTTATGAATATGGATATCGTCCAGTAGTAAATGATTATGAAGTTACAGAGATTATTGAGCAAACAGCA
TTACAACTTTATGGAAGGGAACGAGTTACTCGTTTACAGCCGACGATGGCTGGAGAAGATTTTTCAGCATTTTTACAAAA
AGCACCAGGAACATTCTTTTTTATCGGAGCAGGAAATAAAGAGAAAGGAATTATATATCCTCACCATCACCCTCGTTTTA
CGATTGATGAAGATGCATTACCGATTGGCGTGGAAGTCTTTGTATCATCGATTATGAATTTCATAAATAAAGGAGAATGA

Upstream 100 bases:

>100_bases
AAGTCATCTTTTTGATGGCTTTTTATTTTTAAATGTTTATAACGGAAAATTCAGAAGATTCTTTTAAAAGTTAACAATTC
ACGTTATAATAACATTTAAC

Downstream 100 bases:

>100_bases
GATGAAGAAAATACACGTATTAGCGCTTATTCCAGTTTTTTGTTTAGTTGTTGGACCCGTATTTGCTAATTCAGTTACTC
CTTACATATTAGGGATGCCA

Product: N-acyl-L-amino acid amidohydrolase

Products: NA

Alternate protein names: L-aminoacylase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MVKKGRRKMDVAKELVLSKDQLIEWRRHFHKYPELSFQEEKTSQFVFDILRKIPHLEVSRPTKYSVMARLIGKQSGKTIA
VRADMDALPIHEENEFDFISAYPGVMHACGHDGHIAILLGVVHKLVEAREKIKGEVRFLFQHAEENFPGGAEEMVAAGVM
EGVDYIIGAHLWASLHVGKVGVIYGPAMAAPDVFKITIEGKGGHAGIPHETVDSIAIGTQVVSQLQQIVSRLTNPLDSLV
VSVTQFHAGTTHNVIPEQAEIEGTVRSLRHELREETEKRIEQIVKHVTEAYGAKYTFSYEYGYRPVVNDYEVTEIIEQTA
LQLYGRERVTRLQPTMAGEDFSAFLQKAPGTFFFIGAGNKEKGIIYPHHHPRFTIDEDALPIGVEVFVSSIMNFINKGE

Sequences:

>Translated_399_residues
MVKKGRRKMDVAKELVLSKDQLIEWRRHFHKYPELSFQEEKTSQFVFDILRKIPHLEVSRPTKYSVMARLIGKQSGKTIA
VRADMDALPIHEENEFDFISAYPGVMHACGHDGHIAILLGVVHKLVEAREKIKGEVRFLFQHAEENFPGGAEEMVAAGVM
EGVDYIIGAHLWASLHVGKVGVIYGPAMAAPDVFKITIEGKGGHAGIPHETVDSIAIGTQVVSQLQQIVSRLTNPLDSLV
VSVTQFHAGTTHNVIPEQAEIEGTVRSLRHELREETEKRIEQIVKHVTEAYGAKYTFSYEYGYRPVVNDYEVTEIIEQTA
LQLYGRERVTRLQPTMAGEDFSAFLQKAPGTFFFIGAGNKEKGIIYPHHHPRFTIDEDALPIGVEVFVSSIMNFINKGE
>Mature_399_residues
MVKKGRRKMDVAKELVLSKDQLIEWRRHFHKYPELSFQEEKTSQFVFDILRKIPHLEVSRPTKYSVMARLIGKQSGKTIA
VRADMDALPIHEENEFDFISAYPGVMHACGHDGHIAILLGVVHKLVEAREKIKGEVRFLFQHAEENFPGGAEEMVAAGVM
EGVDYIIGAHLWASLHVGKVGVIYGPAMAAPDVFKITIEGKGGHAGIPHETVDSIAIGTQVVSQLQQIVSRLTNPLDSLV
VSVTQFHAGTTHNVIPEQAEIEGTVRSLRHELREETEKRIEQIVKHVTEAYGAKYTFSYEYGYRPVVNDYEVTEIIEQTA
LQLYGRERVTRLQPTMAGEDFSAFLQKAPGTFFFIGAGNKEKGIIYPHHHPRFTIDEDALPIGVEVFVSSIMNFINKGE

Specific function: Hydrolyzes most efficiently N-acetyl derivatives of aromatic amino acids but is also active on other amino acids. L- stereospecific [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=424, Percent_Identity=25.4716981132075, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.14 [H]

Molecular weight: Translated: 44783; Mature: 44783

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKGRRKMDVAKELVLSKDQLIEWRRHFHKYPELSFQEEKTSQFVFDILRKIPHLEVSR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PTKYSVMARLIGKQSGKTIAVRADMDALPIHEENEFDFISAYPGVMHACGHDGHIAILLG
CHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCHHHHHCCCCCHHHHHHH
VVHKLVEAREKIKGEVRFLFQHAEENFPGGAEEMVAAGVMEGVDYIIGAHLWASLHVGKV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
GVIYGPAMAAPDVFKITIEGKGGHAGIPHETVDSIAIGTQVVSQLQQIVSRLTNPLDSLV
EEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
VSVTQFHAGTTHNVIPEQAEIEGTVRSLRHELREETEKRIEQIVKHVTEAYGAKYTFSYE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
YGYRPVVNDYEVTEIIEQTALQLYGRERVTRLQPTMAGEDFSAFLQKAPGTFFFIGAGNK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
EKGIIYPHHHPRFTIDEDALPIGVEVFVSSIMNFINKGE
CCCEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKKGRRKMDVAKELVLSKDQLIEWRRHFHKYPELSFQEEKTSQFVFDILRKIPHLEVSR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PTKYSVMARLIGKQSGKTIAVRADMDALPIHEENEFDFISAYPGVMHACGHDGHIAILLG
CHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCHHHHHCCCCCHHHHHHH
VVHKLVEAREKIKGEVRFLFQHAEENFPGGAEEMVAAGVMEGVDYIIGAHLWASLHVGKV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
GVIYGPAMAAPDVFKITIEGKGGHAGIPHETVDSIAIGTQVVSQLQQIVSRLTNPLDSLV
EEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
VSVTQFHAGTTHNVIPEQAEIEGTVRSLRHELREETEKRIEQIVKHVTEAYGAKYTFSYE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
YGYRPVVNDYEVTEIIEQTALQLYGRERVTRLQPTMAGEDFSAFLQKAPGTFFFIGAGNK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
EKGIIYPHHHPRFTIDEDALPIGVEVFVSSIMNFINKGE
CCCEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8285691; 9023955 [H]