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The map label for this gene is rocE [H]

Identifier: 118476329

GI number: 118476329

Start: 681085

End: 682506

Strand: Direct

Name: rocE [H]

Synonym: BALH_0585

Alternate gene names: 118476329

Gene position: 681085-682506 (Clockwise)

Preceding gene: 118476328

Following gene: 118476330

Centisome position: 12.96

GC content: 37.48

Gene sequence:

>1422_bases
ATGCAGCAACCAACGAATGAGAAATTACATCGTACGATGAAGAGTAGACATTTATTTATGATCGCACTAGGTGGTGTAAT
CGGGACGGGCTTTTTCTTGGGTTCTGGTTACACCATTAATCAGGCTGGACCAGGGGGAGCCATCCTTTCCTATTTAGTGG
GCGGATTTATTATGTATTTAACAATGCTATGCCTTGGAGAGTTAACGGTAGCAATGCCAGTTTCAGGATCTTTCCAAAAG
TATGCGACGAAGTTTATTGGACCAGGAACGGGCTTTATGATCGGCTGGCTATATTGGCTTGGTTGGGCAGTAACAGTAGG
ACTAGAATTAACGTCAATCGGTTTAATGATGAAGAGATGGTTTCCGAATGTTGATGTTTGGGTATGGTGTCTCGTTTTCG
GCGTTATTTTATATGCTTCAAACGCAATTTCAGCGAAAAGTTATGCTGAATTAGAATTTTGGTTCTCTAGTATTAAAGTA
ATTACAATTCTTGCATTTGTTGTTCTTGGTGGTAGTGCATTATTAGGGTTTATATCATATGACGGAAAAGAAGCAGCACC
TCTTTTCTCTAACTTTGTAAGCGAAGGCGGGTTATTCCCGAATGGACTAGCTGCCGTATTACTTACAATGATTACAGTTA
ACTTCTCGTTCCAAGGAACAGAGTTAATCGGGATTGCAGCGGGAGAAAGTGAAAATCCAGAAAAAACAATTCCACGTGCC
ATCCGTAATACAGTATGGCGCATTATGTTATTCTTCATTTTAACAATGACGATTTTAGTAGGATTAATTTCTTGGAAAGA
AGCAGGGGTAATTGAAAGTCCATTTGTAGTTGTATTTGATAAAATTGGTATTCCATACGCAGCTGATATTATGAACTTCG
TTATTATTACAGCGTTACTATCTGTAGCGAATTCAGGATTATATGCGGCAACTCGTATACTATGGTCACTTGCAAATGAA
GGAATGGCACCAGCATCTTTCCAGAAAGTAAATAAGCGTGGGATTCCAATTACAGCACTAGTTGTAACGATTGCGGTAGC
TGGCCTTTCTTTATTCACAAGTTTCCTTGCAGAAGATACAGTATACATGTACTTATTATCTATAGCTGGTTTATCAGCTG
TTTCAAGTTGGATCATTATTGCTTTATCACAACTTCGCTTTAGAAGTCAGTATATAAAAGGCGGAGGAAAGTTAGAGGAC
TTAAAATATAGAACACCGTTATATCCAATTGTTCCTATTTTAGCTTTAATTACAAATAGTATCGTTGTTATTAGTTTAGC
GTTTATTCCAGAACAAAGAATGGCGTTATATTGTGGTATTCCATTTATCATTTTCTGCTACATATATTATTATATAAATA
AGAAACGGCAGAAACCGATGAAGGTGGAGACAACAAATGAAACTAACAATCAAACACGATGA

Upstream 100 bases:

>100_bases
AGTTTTAATTTTATATAGAAAATGTAATCGCTTTCGTGTATATTTTTATTATCAGAAAATTTTAACAAGATATAGGGGTA
TTGGTAGGGGGAGGATTTAG

Downstream 100 bases:

>100_bases
TATTGAGGCAGATTTATCGTATGGTCCATTAGCGATTGGAAAAGAAAACGGATATTCACCGTTACAATTACTCGTTTCTT
CTATCGCAGGATGTAGTGCA

Product: arginine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPASFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVETTNETNNQTR

Sequences:

>Translated_473_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPASFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVETTNETNNQTR
>Mature_473_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPASFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVETTNETNNQTR

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=353, Percent_Identity=25.7790368271955, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI71999149, Length=350, Percent_Identity=23.1428571428571, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258645169, Length=424, Percent_Identity=22.877358490566, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081708, Length=462, Percent_Identity=50.6493506493506, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1788480, Length=479, Percent_Identity=41.3361169102296, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI1786302, Length=461, Percent_Identity=36.0086767895879, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1786789, Length=455, Percent_Identity=36.4835164835165, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789017, Length=434, Percent_Identity=36.6359447004608, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI48994972, Length=463, Percent_Identity=33.9092872570194, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=37.6847290640394, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1786602, Length=457, Percent_Identity=35.4485776805252, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=32.7586206896552, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI87081869, Length=239, Percent_Identity=25.5230125523013, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367353, Length=325, Percent_Identity=25.2307692307692, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=360, Percent_Identity=24.7222222222222, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=427, Percent_Identity=21.7798594847775, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=441, Percent_Identity=24.2630385487528, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=440, Percent_Identity=32.9545454545455, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=33.4916864608076, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6320717, Length=486, Percent_Identity=30.2469135802469, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=31.358024691358, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=31.5909090909091, Blast_Score=219, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6319824, Length=490, Percent_Identity=29.7959183673469, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324990, Length=473, Percent_Identity=29.5983086680761, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320251, Length=421, Percent_Identity=31.5914489311164, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6322892, Length=472, Percent_Identity=30.9322033898305, Blast_Score=206, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6319542, Length=415, Percent_Identity=31.8072289156626, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6321629, Length=417, Percent_Identity=29.7362110311751, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6319543, Length=420, Percent_Identity=29.7619047619048, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6322967, Length=483, Percent_Identity=28.7784679089027, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321053, Length=417, Percent_Identity=26.378896882494, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=451, Percent_Identity=28.8248337028825, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=494, Percent_Identity=28.3400809716599, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319608, Length=439, Percent_Identity=25.7403189066059, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320364, Length=507, Percent_Identity=23.4714003944773, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24667468, Length=416, Percent_Identity=24.7596153846154, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=19.7215777262181, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=19.7215777262181, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52009; Mature: 52009

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPASFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVETTNETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPASFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVETTNETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]