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The map label for this gene is yfkJ [H]

Identifier: 118476160

GI number: 118476160

Start: 465772

End: 466296

Strand: Direct

Name: yfkJ [H]

Synonym: BALH_0407

Alternate gene names: 118476160

Gene position: 465772-466296 (Clockwise)

Preceding gene: 118476157

Following gene: 118476161

Centisome position: 8.86

GC content: 37.14

Gene sequence:

>525_bases
TTGGTTGTTTATACTATAAGTATATATAAAGAAATGCACCAAGAAGGGAAGAAACAAAATATGGTTCAAGTATTGTTTGT
TTGTCTTGGGAACATTTGCCGTTCTCCGATGGCAGAAGCGATTTTTCGAGATCTTGTCGTAAAAGAGGGACTCGAAGAGA
AAATTGTCATTGATTCTGCAGGAACTGGAGATTGGCATGTTGGTCATCCGCCACATAAAGGAACACAAAAAATTTTAAAA
GAAAATGCAGTCACTTTTGAAGGAATTAAAGCAAGGCAAGTAGAAAAAGAAGACTTAACAAAGTTTGATTATATTATTGC
CATGGACAACAAGAATATAGCAGATTTAAAAAGTTTAGGTAAAACTGGAGGCTATATTGGTAGGCTGTCCGATTTTGTTC
CAGACGGTGGCTGGACAGACGTTCCCGACCCTTACTATACAGGGAATTTCCAAGAAGTATATGACCTTGTAACAGAAGGG
TGTGCAAAGCTATTAGCTTTCATTCGAAATGAACAAGGAATATGA

Upstream 100 bases:

>100_bases
TTTAAAATAACATAAGGTTATCTTAACATTTTTTATCATTTTCGTTAATGAATCTTTTCAATCCTATTAAATTAGTAGGG
ATTTCCTTTATATTTAATAA

Downstream 100 bases:

>100_bases
GGAAGCTTAGAAAGAAATACTTTCTAACATAAGAAATGAAAGGGTGAAGGAATATGGCAAAGAAAAATAATATTGCTCGA
AACATTGCGATTGGTGTAGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MVVYTISIYKEMHQEGKKQNMVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILK
ENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEG
CAKLLAFIRNEQGI

Sequences:

>Translated_174_residues
MVVYTISIYKEMHQEGKKQNMVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILK
ENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEG
CAKLLAFIRNEQGI
>Mature_174_residues
MVVYTISIYKEMHQEGKKQNMVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSAGTGDWHVGHPPHKGTQKILK
ENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLGKTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEG
CAKLLAFIRNEQGI

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=154, Percent_Identity=38.961038961039, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI4757714, Length=154, Percent_Identity=37.6623376623377, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI96304457, Length=82, Percent_Identity=45.1219512195122, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=136, Percent_Identity=39.7058823529412, Blast_Score=91, Evalue=9e-20,
Organism=Drosophila melanogaster, GI78706770, Length=162, Percent_Identity=37.6543209876543, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI78706772, Length=162, Percent_Identity=37.6543209876543, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI78711846, Length=165, Percent_Identity=36.3636363636364, Blast_Score=106, Evalue=9e-24,
Organism=Drosophila melanogaster, GI78706766, Length=148, Percent_Identity=33.7837837837838, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706768, Length=148, Percent_Identity=33.7837837837838, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=36.1538461538462, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648069, Length=151, Percent_Identity=33.7748344370861, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 19503; Mature: 19503

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVYTISIYKEMHQEGKKQNMVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECC
GTGDWHVGHPPHKGTQKILKENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCHHHHHHHH
KTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI
HCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVYTISIYKEMHQEGKKQNMVQVLFVCLGNICRSPMAEAIFRDLVVKEGLEEKIVIDSA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECC
GTGDWHVGHPPHKGTQKILKENAVTFEGIKARQVEKEDLTKFDYIIAMDNKNIADLKSLG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCHHHHHHHH
KTGGYIGRLSDFVPDGGWTDVPDPYYTGNFQEVYDLVTEGCAKLLAFIRNEQGI
HCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]