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The map label for this gene is qacR [H]

Identifier: 118476144

GI number: 118476144

Start: 447153

End: 447740

Strand: Direct

Name: qacR [H]

Synonym: BALH_0389

Alternate gene names: 118476144

Gene position: 447153-447740 (Clockwise)

Preceding gene: 118476143

Following gene: 118476145

Centisome position: 8.51

GC content: 31.97

Gene sequence:

>588_bases
GTGAATATGAGAAGAAGTGCAGAAGAGATAAAGAAAGAAATTGCATATAAAGCAGAAATTTTATTTTCACAGAAGGGCTA
TGCAGCCACATCTATGGAAGAGATTTGTGAAATTACAGAGAGAAGTAAAGGAAGCATTTATTATCACTTTAAAAGTAAAG
AAGAATTATTTTTATTTGTAGTAAAGCAGCATACGTATGATTGGCTTGAAAAATGGAATGAAAAAGAGAAGTTGTATAGT
ACTAGCACTGAGAAATTGTATGCCTTAGCAGAATATCATGTAGAGGATATACAACAACCTATTTCTAATGCAATAGAAGA
ATTTTCTATGAGCCAAGTTGTAAGCAAAGAAATTTTGGATGAAATGTTAGCTTTAACTAGAGAATCGTATGTTATGTTTG
AGACATTAATTGAAGCAGGCATACAGTCTGGAGAGTTTCGTGAAGATAATACGCGCGATCTTATGTATATTGTGAATGGA
TTATTATCAGGGCTGGGAGTACTTTATTACGAGTTAGATTATAAAGAATTGAAACGTATTTATAAAAAGGCGATAGATGT
ATTGTTAAAAGGAATGGCAGCTGAATAA

Upstream 100 bases:

>100_bases
AAGTGAAAAATAAGGGGAAAGTAATGTTATTTTTATTAGACTCTTGTAATAGAGGTTTTTAATTTGTTATTATTAGACTG
AACGGTCGGTTTAAAGAGGT

Downstream 100 bases:

>100_bases
TAGGTCAGTTGCTTTTCTTACAAAATAAATTAGACCGAACGGTCGGTTTATGGAAGGAGAATAAAAATGAACGCTTTATT
TAAAAATCGAGCATTTATGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNMRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYS
TSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNG
LLSGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Sequences:

>Translated_195_residues
MNMRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYS
TSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNG
LLSGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE
>Mature_195_residues
MNMRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYS
TSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNG
LLSGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Specific function: Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013571
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08360 TetR_C_5; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22875; Mature: 22875

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHH
VKQHTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILD
HHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLGVLYYELDYKELKRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YKKAIDVLLKGMAAE
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHH
VKQHTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILD
HHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLGVLYYELDYKELKRI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YKKAIDVLLKGMAAE
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]