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The map label for this gene is insK [H]

Identifier: 118476064

GI number: 118476064

Start: 353517

End: 354257

Strand: Direct

Name: insK [H]

Synonym: BALH_0307

Alternate gene names: 118476064

Gene position: 353517-354257 (Clockwise)

Preceding gene: 118476063

Following gene: 118476068

Centisome position: 6.72

GC content: 35.09

Gene sequence:

>741_bases
ATGAACAACATGCGACTAGAATCCGATAAACGATTAAAAAAGGTAATTCAATCTATTCACGTAAAGCACAAAGAATATGG
ATATCCACGTATGAAAATCGCTTTAGAAGAAGAGGGATATTTTATAAATCACAAAAAGGTATATCGATTAATGAGTGAGC
TTAACATTCAGTCTATTATTCGAAAGAAGCGTCGCTTCTTTAAAGGGAATTATTCTAATACTTTTCCAAATGTTTTAAAC
CGTGAATTCAAAGATCGCCAACAAAATGAAGCGCTTGTTACAGACATTACCTACCTACGATTTCAAGAGGGCTTCCGCTA
TCTTTCTGTTGTACAAGATATTTATAATAACGAAGTTGTTTCTTGGAAAATTTCCAAGCGTAACGATAATGAACTTGTAT
TAGATACAATTGAAATGTTGGCACAAAAAAGAGATGTGCGTGGAACCATTCTCCACTCAGATCAGGGGTTCCAGTACACA
TCTCATGCCTACAACAAACGACTTTTAGATTTAGGTATCATTGGCAGCCACTCTCGCAAAGGAAACTGCCATGATAATGC
CTGTATCGAGTCATTTTTCTCCCATTTTAAATCGGAGATGTTGTATTTGAATCATTTTAAAACAGAAGCGGATTTAATAC
AAGCAATTGAAGAATATATTTACTTTTATAACTATAAACGTTTCCAAAAACGACTCAACCATCGAGCTCCGATAGAATAT
CGAATCTCGATGGCTGCTTAG

Upstream 100 bases:

>100_bases
TATCATTGAATTACTAAAGAGAAAATATCCTGTTATATGGCTTACTAAATTTGCGGGTGTACATCGCTCAAGTTACTATA
AGTGGGTTCATACAAAAAGT

Downstream 100 bases:

>100_bases
TCTTTTTAATACTGTCTACTTGACAGGGATAAGACCATTCCTGGTCTTTTTTTATTACTGAAAGCAGCTAGCGAGTAGTA
AGGTAATCCAAATGATAATG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNNMRLESDKRLKKVIQSIHVKHKEYGYPRMKIALEEEGYFINHKKVYRLMSELNIQSIIRKKRRFFKGNYSNTFPNVLN
REFKDRQQNEALVTDITYLRFQEGFRYLSVVQDIYNNEVVSWKISKRNDNELVLDTIEMLAQKRDVRGTILHSDQGFQYT
SHAYNKRLLDLGIIGSHSRKGNCHDNACIESFFSHFKSEMLYLNHFKTEADLIQAIEEYIYFYNYKRFQKRLNHRAPIEY
RISMAA

Sequences:

>Translated_246_residues
MNNMRLESDKRLKKVIQSIHVKHKEYGYPRMKIALEEEGYFINHKKVYRLMSELNIQSIIRKKRRFFKGNYSNTFPNVLN
REFKDRQQNEALVTDITYLRFQEGFRYLSVVQDIYNNEVVSWKISKRNDNELVLDTIEMLAQKRDVRGTILHSDQGFQYT
SHAYNKRLLDLGIIGSHSRKGNCHDNACIESFFSHFKSEMLYLNHFKTEADLIQAIEEYIYFYNYKRFQKRLNHRAPIEY
RISMAA
>Mature_246_residues
MNNMRLESDKRLKKVIQSIHVKHKEYGYPRMKIALEEEGYFINHKKVYRLMSELNIQSIIRKKRRFFKGNYSNTFPNVLN
REFKDRQQNEALVTDITYLRFQEGFRYLSVVQDIYNNEVVSWKISKRNDNELVLDTIEMLAQKRDVRGTILHSDQGFQYT
SHAYNKRLLDLGIIGSHSRKGNCHDNACIESFFSHFKSEMLYLNHFKTEADLIQAIEEYIYFYNYKRFQKRLNHRAPIEY
RISMAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=198, Percent_Identity=32.8282828282828, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1789981, Length=231, Percent_Identity=41.5584415584416, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1788405, Length=221, Percent_Identity=32.579185520362, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787263, Length=221, Percent_Identity=32.579185520362, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786753, Length=221, Percent_Identity=32.579185520362, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786570, Length=221, Percent_Identity=32.579185520362, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786490, Length=221, Percent_Identity=32.579185520362, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 29588; Mature: 29588

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMRLESDKRLKKVIQSIHVKHKEYGYPRMKIALEEEGYFINHKKVYRLMSELNIQSII
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECHHHHHHHHHHCCHHHHH
RKKRRFFKGNYSNTFPNVLNREFKDRQQNEALVTDITYLRFQEGFRYLSVVQDIYNNEVV
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SWKISKRNDNELVLDTIEMLAQKRDVRGTILHSDQGFQYTSHAYNKRLLDLGIIGSHSRK
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCCCCC
GNCHDNACIESFFSHFKSEMLYLNHFKTEADLIQAIEEYIYFYNYKRFQKRLNHRAPIEY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
RISMAA
EEEECC
>Mature Secondary Structure
MNNMRLESDKRLKKVIQSIHVKHKEYGYPRMKIALEEEGYFINHKKVYRLMSELNIQSII
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECHHHHHHHHHHCCHHHHH
RKKRRFFKGNYSNTFPNVLNREFKDRQQNEALVTDITYLRFQEGFRYLSVVQDIYNNEVV
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SWKISKRNDNELVLDTIEMLAQKRDVRGTILHSDQGFQYTSHAYNKRLLDLGIIGSHSRK
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCCCCC
GNCHDNACIESFFSHFKSEMLYLNHFKTEADLIQAIEEYIYFYNYKRFQKRLNHRAPIEY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
RISMAA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]