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The map label for this gene is gcp

Identifier: 118476008

GI number: 118476008

Start: 264918

End: 265949

Strand: Direct

Name: gcp

Synonym: BALH_0246

Alternate gene names: 118476008

Gene position: 264918-265949 (Clockwise)

Preceding gene: 118476007

Following gene: 118476010

Centisome position: 5.04

GC content: 40.02

Gene sequence:

>1032_bases
GTGGGTGAATATATAATGGAAAAAAATACGATTATACTTGGTATTGAAACAAGTTGTGATGAAACAGCAGTAGCGGTTGT
TAAAAATGGAACGGAAATTATTGCGAATGTCGTTGCATCACAAATTGAAAGTCATAAACGTTTTGGCGGAGTTGTACCAG
AGATTGCATCTCGTCATCATGTAGAAGAAATTACAGTTGTGTTAGAAGAAGCTTTAAAAGAAGCGAATATCACATTTGAT
GATATTGATGCAATTGCTGTAACAGAAGGACCTGGTTTAGTAGGAGCACTTCTAATAGGGGTAAATGCAGCGAAAGCAGT
GGCATTTGCACATGATATCCCTCTAGTTGGTGTTCATCATATCGCTGGCCACATTTATGCGAACCGTTTAGTAAAAGAAG
TTCAATTCCCATTACTATCACTTGTTGTATCTGGTGGACATACAGAGCTTGTTTATATGAAAGAACATGGTTCGTTTGAA
GTAATTGGTGAAACGCGAGATGATGCAGCAGGAGAAGCATATGATAAAGTAGCTCGTACGTTATCTATGCCATATCCAGG
GGGTCCTCATATTGATCGCCTTGCACATGAAGGGAAACCAACAATCGATTTACCTCGTGCATGGCTTGAACCTGATTCGT
ATGATTTCAGTTTTAGTGGATTAAAATCAGCAGTTATCAACACTGTGCATAACGCAAAACAACGCGGGATAGAAATTGCA
CCGGAAGATTTAGCGGCAAGTTTCCAAGAGAGTGTCATTGACGTACTAGTAACGAAAGCATCTCGTGCAGCGGATGCTTA
TAACGTAAAGCAAGTGCTTCTTGCTGGTGGAGTGGCTGCTAATAAAGGGCTTCGTGCACGCTTAGAAGCAGAATTTGCAC
AAAAAGAAAATGTAGAGCTAATTATTCCTCCTCTATCTTTATGCACAGATAATGCAGCAATGATTGCGGCGGCAGGTACA
ATTGCATATGAACAAGGAAAACGTGCTACATTAGCTTTAAATGCAAATCCAGGATTAGATATCGAAGCATAG

Upstream 100 bases:

>100_bases
CAAATGAGGTAGCAAAACAGTTATACAGAAAATACGGATTTCAAAATGGTGGAATTCGTAAACGATACTATGCAGACAAT
CAGGAAGATGGTCTCGTAAT

Downstream 100 bases:

>100_bases
TTATGCACAAAATTAACCACAGCTTGTGGATAAAACCCATATTATCTGTTGATAATGTGGGTTTTATTGTGTATATAAAA
TGTTGATAACTTTTTTGTTA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFD
DIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFE
VIGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIA
PEDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGT
IAYEQGKRATLALNANPGLDIEA

Sequences:

>Translated_343_residues
MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFD
DIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFE
VIGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIA
PEDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGT
IAYEQGKRATLALNANPGLDIEA
>Mature_342_residues
GEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDD
IDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEV
IGETRDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAP
EDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGTI
AYEQGKRATLALNANPGLDIEA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI8923380, Length=325, Percent_Identity=36.6153846153846, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI116812636, Length=333, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=8e-41,
Organism=Escherichia coli, GI1789445, Length=328, Percent_Identity=43.9024390243902, Blast_Score=281, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=32.8220858895706, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=32.3076923076923, Blast_Score=147, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.048433048433, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=30.4597701149425, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20129063, Length=358, Percent_Identity=31.2849162011173, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=31.6109422492401, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_BACAH (A0R8V9)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_893159.1
- ProteinModelPortal:   A0R8V9
- SMR:   A0R8V9
- STRING:   A0R8V9
- EnsemblBacteria:   EBBACT00000067192
- GeneID:   4546579
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_0246
- NMPDR:   fig|412694.5.peg.300
- eggNOG:   COG0533
- GeneTree:   EBGT00050000002496
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   BTHU412694:BALH_0246-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36537; Mature: 36406

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHH
CCCCEEECCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VEEITVVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHH
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHH
IAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVART
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
LSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIA
HCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEC
PEDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEE
IIPPLSLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
EECCHHHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
GEYIMEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHH
CCCEEECCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VEEITVVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHH
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHH
IAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVART
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
LSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIA
HCCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEC
PEDLAASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEE
IIPPLSLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
EECCHHHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA