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The map label for this gene is slyD [H]

Identifier: 117919587

GI number: 117919587

Start: 1341513

End: 1342181

Strand: Reverse

Name: slyD [H]

Synonym: Shewana3_1138

Alternate gene names: 117919587

Gene position: 1342181-1341513 (Counterclockwise)

Preceding gene: 117919594

Following gene: 117919586

Centisome position: 26.99

GC content: 49.93

Gene sequence:

>669_bases
ATGAAGATCACCCAACACAGCGCGGTAACCATTCATTACCGTTTATCAGATCAAGACGGCAGACTTTTAGAAGACTCTTT
TGATGCCGAACCTATGCTCTATCTGCACGGTGCAGAAAACCTGATCCCAGGATTAGAAGCTGCATTAGAAGGTAAAACCA
AGGGCGAAACACTGGATGTGACTATTAGTGCCGAAGAAGCCTACGGTCCTTACCACGATGGTCTGCGTCAAGCTGTGCCA
TTAGAAGCATTCGGTGATATCGAAGATATCGTTCCTGGTATGCGCTTTATTGCCGAGACAGAAATGGGTCAACGCCCAGT
GCAAGTTGTCGAAGTCAAAGATGATGTGGTCATCGTTGATGGCAACCATCCTTTAGCGGGACAAGCACTGAGCTTCAACA
TTGAAATTATCGATGTTCGCGCTGCAACTGCAGAAGAAGTTGCCCATGGCCATATCCATGCCCACGGCGGATGTGGTAGC
CATGGACACAGCCATGATCATGACCACGGCGGCGGATGCTGTGGTGGTTCAAGCCAAGATGCGGGTGGCTGTTGTGGCGG
TTCTGATGATCATGGTCATCATCACCATGACCATGATCACGATCATGAAGCATGCGACACACCAAAAACAGGTTGTGATG
GCAATGGCGGTTGCGGTTGCCGCGGCTAA

Upstream 100 bases:

>100_bases
CAACAAAAAGCTGTGCGATATCTAACATAAGCAACTTCAAATTATCGCCAGCGCCCTAAAAGCACGTTATTATGCGCGCA
CATTCCGAACCGGAGGCGAT

Downstream 100 bases:

>100_bases
TCTAGGCCGTAACGCCTAAAGCTCACTAACCTGAGCAAGATAATGAAGCACTTCCTTACATAAGGAGGTGCTTTTTTTTA
TCCACAAATGTTTATAATCC

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKITQHSAVTIHYRLSDQDGRLLEDSFDAEPMLYLHGAENLIPGLEAALEGKTKGETLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVVEVKDDVVIVDGNHPLAGQALSFNIEIIDVRAATAEEVAHGHIHAHGGCGS
HGHSHDHDHGGGCCGGSSQDAGGCCGGSDDHGHHHHDHDHDHEACDTPKTGCDGNGGCGCRG

Sequences:

>Translated_222_residues
MKITQHSAVTIHYRLSDQDGRLLEDSFDAEPMLYLHGAENLIPGLEAALEGKTKGETLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVVEVKDDVVIVDGNHPLAGQALSFNIEIIDVRAATAEEVAHGHIHAHGGCGS
HGHSHDHDHGGGCCGGSSQDAGGCCGGSDDHGHHHHDHDHDHEACDTPKTGCDGNGGCGCRG
>Mature_222_residues
MKITQHSAVTIHYRLSDQDGRLLEDSFDAEPMLYLHGAENLIPGLEAALEGKTKGETLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVVEVKDDVVIVDGNHPLAGQALSFNIEIIDVRAATAEEVAHGHIHAHGGCGS
HGHSHDHDHGGGCCGGSSQDAGGCCGGSDDHGHHHHDHDHDHEACDTPKTGCDGNGGCGCRG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=45.945945945946, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 23453; Mature: 23453

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITQHSAVTIHYRLSDQDGRLLEDSFDAEPMLYLHGAENLIPGLEAALEGKTKGETLDV
CCCCCCCEEEEEEEECCCCCCEECCCCCCCCEEEEECCCHHCCCHHHHHCCCCCCCEEEE
TISAEEAYGPYHDGLRQAVPLEAFGDIEDIVPGMRFIAETEMGQRPVQVVEVKDDVVIVD
EEECHHHCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQALSFNIEIIDVRAATAEEVAHGHIHAHGGCGSHGHSHDHDHGGGCCGGSSQD
CCCCCCCCEEEEEEEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCEECCCCCCC
AGGCCGGSDDHGHHHHDHDHDHEACDTPKTGCDGNGGCGCRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITQHSAVTIHYRLSDQDGRLLEDSFDAEPMLYLHGAENLIPGLEAALEGKTKGETLDV
CCCCCCCEEEEEEEECCCCCCEECCCCCCCCEEEEECCCHHCCCHHHHHCCCCCCCEEEE
TISAEEAYGPYHDGLRQAVPLEAFGDIEDIVPGMRFIAETEMGQRPVQVVEVKDDVVIVD
EEECHHHCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQALSFNIEIIDVRAATAEEVAHGHIHAHGGCGSHGHSHDHDHGGGCCGGSSQD
CCCCCCCCEEEEEEEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCEECCCCCCC
AGGCCGGSDDHGHHHHDHDHDHEACDTPKTGCDGNGGCGCRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]