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The map label for this gene is tpiA [H]

Identifier: 117919475

GI number: 117919475

Start: 1198659

End: 1199441

Strand: Direct

Name: tpiA [H]

Synonym: Shewana3_1026

Alternate gene names: 117919475

Gene position: 1198659-1199441 (Clockwise)

Preceding gene: 117919474

Following gene: 117919476

Centisome position: 24.11

GC content: 47.51

Gene sequence:

>783_bases
ATGGCACTCAGACGTCCTATGGTAGCTGGCAATTGGAAGATGAACGGCAGCGCGGCATTAGCCCAAGAGTTGTTCAAGAA
ATTTGCCTCAAAGCTCCAAAATGATTCAGCTGAAGTGGTTTTATGCCCGCCTTCTATCTATCTAGAAAGCGTAAGGCAAC
TGCTAGAAGCAAACAAGGAAGCGTTAGACGGTTCACTTGTTAGGATGGGCGCTCAGAATTTAAGTCAACATGACTTTGGC
GCTTATACCGGAGAAGTTTCGGGTCAGATGCTTAAAGATTGCGGATGTCGATATGTCATTATCGGGCATTCAGAACGTCG
CCGTATGTACGGAGAGACGAGTAATATCGTAGCGGAGAAATTCGCTGCAGCACAAAAGCACGGTTTAACCCCCATTTTAT
GCGTGGGTGAGTCGGGTCCAGCACGTGAAGCAAGACGTACCTTCGAGGTGATTGCGGAAGAGTTGGATATAGTGATCCAG
AAAAATGGCACTATGGCTTTTGATAACGCCATTATCGCTTACGAGCCGTTATGGGCGGTAGGGACTGGTAAGAGCGCGAC
ACCAGAGCAGGCACAAGAAGTACATGCGTTTATACGCAAGCGTCTCTCTGAAGTGTCTCCGTTTATCGGAGAAAATATCA
GGATTTTGTACGGTGGCAGTGTGACACCGAGTAATGCGGCAGATTTATTTGCCCAACCTGATGTTGATGGTGGACTGATT
GGCGGTGCCAGTTTAAACTCTACCGAGTTTTTAAGTCTGTGTACCATAGCGATGAGCGCATAA

Upstream 100 bases:

>100_bases
AGTAAGCATTCCAACCTAATATCTGAAAAATTTCGAATTTAGCTATTGTAACTTAATAAGTGGTTCGCTATTATTCACGC
CGCTTTCAGAGGAGACAGTG

Downstream 100 bases:

>100_bases
TATGTATGAAGTTTTAGTAGTTGTTTACTTGTTGGTTGCATTAGGTTTAATTGGCCTGATCTTAATCCAGCAAGGCAAAG
GAGCTGACATGGGTGCCTCA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKEALDGSLVRMGAQNLSQHDFG
AYTGEVSGQMLKDCGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQ
KNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
GGASLNSTEFLSLCTIAMSA

Sequences:

>Translated_260_residues
MALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKEALDGSLVRMGAQNLSQHDFG
AYTGEVSGQMLKDCGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQ
KNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
GGASLNSTEFLSLCTIAMSA
>Mature_259_residues
ALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKEALDGSLVRMGAQNLSQHDFGA
YTGEVSGQMLKDCGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQK
NGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLIG
GASLNSTEFLSLCTIAMSA

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=252, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI226529917, Length=252, Percent_Identity=42.8571428571429, Blast_Score=197, Evalue=9e-51,
Organism=Escherichia coli, GI1790353, Length=259, Percent_Identity=47.8764478764479, Blast_Score=252, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17536593, Length=244, Percent_Identity=44.2622950819672, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320255, Length=251, Percent_Identity=39.8406374501992, Blast_Score=182, Evalue=4e-47,
Organism=Drosophila melanogaster, GI28572008, Length=251, Percent_Identity=44.6215139442231, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI28572006, Length=251, Percent_Identity=44.6215139442231, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI28572004, Length=251, Percent_Identity=44.6215139442231, Blast_Score=205, Evalue=2e-53,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 28073; Mature: 27942

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKE
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCHH
ALDGSLVRMGAQNLSQHDFGAYTGEVSGQMLKDCGCRYVIIGHSERRRMYGETSNIVAEK
HHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHH
FAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQKNGTMAFDNAIIAYEPLWAV
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEECCEEEE
GTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHHCCCCCCCCCEE
GGASLNSTEFLSLCTIAMSA
CCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKE
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCHH
ALDGSLVRMGAQNLSQHDFGAYTGEVSGQMLKDCGCRYVIIGHSERRRMYGETSNIVAEK
HHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHH
FAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQKNGTMAFDNAIIAYEPLWAV
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEECCEEEE
GTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCHHHCCCCCCCCCEE
GGASLNSTEFLSLCTIAMSA
CCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA