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The map label for this gene is apbE [H]

Identifier: 117919393

GI number: 117919393

Start: 1105032

End: 1106156

Strand: Direct

Name: apbE [H]

Synonym: Shewana3_0944

Alternate gene names: 117919393

Gene position: 1105032-1106156 (Clockwise)

Preceding gene: 117919392

Following gene: 117919394

Centisome position: 22.22

GC content: 46.67

Gene sequence:

>1125_bases
ATGTGGAGTAGAGCTCTCATCTGCAACTTTTGCATTAAAGGGCATCCAAAAGAGTTGTTAGTCACTATGTTTAAAACCCT
AGCGTTAAAAACCCCCGTGTTAAAAACCTCAGTGTTAAAGCATTCAGTGAGCTGGCTGGTCCTTGTAGGTCTAGCCTTTT
TTATTTCAGCCTGTAGCAAACAGGATGAGGTTATCTCCCTCGCGGGCAGCACAATGGGCACGACCTACCACATTAAAGTG
GTTCCCAATGAGCAAATGCCGACGGCCCAGTTACTGCAGGCCGAAATTGACTTAGCCTTAGAGCTGGTCAATAACCAGAT
GTCGACCTATCGACCCAATTCAGAATTGTCTCGTTTCAACCAGTTACCGCTCGAGCAGAGTGTAGAAGTCTCTCCTGATA
CCATCAAAGTGGTTAAAGAAGGCATGCGTTTGTATAACGTGACAGACAAAGCCTTAGACATTACCTTAGGGCCGCTGGTG
AACCTATGGGGATTTGGTCCCGATAAGCGCCCAACCAAAGTGCCGACTCAAGCAGATATCGATGCGGCTAAAGCCAAAAC
CGGTATCAGTGAGCTTTCTATCGAAGGTAATCGCTTAAGCAAACACAATGCGCATTTATATGTGGACCTGTCTTCAATCG
CCAAAGGTTTTGGCGTGGATAAAGTGGCCTCGATTTTAGATAAGTACCATGCAAGTGGCTACTTAGTCGAAATTGGCGGC
GAGCTGAGCATTAAAGGTACTAAAGGCGATGGCAGTTCGTGGCGCGTCGCGATAGAGAAACCGACCGACGATGGCATGGC
GGTGCAACAGGTGATTGAGCCTGGCACTATGGCGATGGCAACGTCGGGGGATTATCGTAATTATTATGAGGAAGAAGGTC
AGCGCTTTACTCATATAATTGATCCACGTACCGGTTTGCCTATTAATCATAAGCTAGCATCTGTGACCGTTTTGCATAAG
AAATGTATGACGGCCGATGGTTTTGCGACGGCGATGATGGTTTTAGGCACAGAAGCGTCATTGGAGCTTGCCAAGAAAGA
ACACTTGGCGATAATGCTAATAGAAAAGCAAGGCGAAGGATTTAAAGTCTACTACAGTGACGCCTTCAAGCCTTTCCTTA
AGTAG

Upstream 100 bases:

>100_bases
TGATCGGTATGTTGAAAAATCTTGGTGTCGAAGACGAAAACATCCTGTTGGATGACTTCGGCGGCTAATGTGAATTAGCC
CAAGGTGAGAAGAGTTGCAG

Downstream 100 bases:

>100_bases
TTGGAGTTAACATGAGCACTTTTATCGCGGCATTTGTGATTTTATTACTGTTCTTTTTGCTTATGTCGATAGGTTATCTC
ATCAAGCGCAAAGCCGTTGA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MWSRALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVSWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALELVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
KCMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK

Sequences:

>Translated_374_residues
MWSRALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVSWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALELVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
KCMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK
>Mature_374_residues
MWSRALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVSWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKV
VPNEQMPTAQLLQAEIDLALELVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLV
NLWGFGPDKRPTKVPTQADIDAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHIIDPRTGLPINHKLASVTVLHK
KCMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=344, Percent_Identity=40.406976744186, Blast_Score=264, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 41123; Mature: 41123

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSRALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVSWLVLVGLAFFISACSK
CCCCCEEHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALELVNNQMSTYRPNSELSRFN
CCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHH
QLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLVNLWGFGPDKRPTKVPTQADI
CCCCCCCCCCCCHHHHHHHHCHHEEECCCHHHEEEHHHHHHHHCCCCCCCCCCCCCCCCC
DAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
HHHHHHCCHHHEEECCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHII
EEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEEE
DPRTGLPINHKLASVTVLHKKCMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEG
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCC
FKVYYSDAFKPFLK
EEEEECCCCHHHCC
>Mature Secondary Structure
MWSRALICNFCIKGHPKELLVTMFKTLALKTPVLKTSVLKHSVSWLVLVGLAFFISACSK
CCCCCEEHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALELVNNQMSTYRPNSELSRFN
CCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHH
QLPLEQSVEVSPDTIKVVKEGMRLYNVTDKALDITLGPLVNLWGFGPDKRPTKVPTQADI
CCCCCCCCCCCCHHHHHHHHCHHEEECCCHHHEEEHHHHHHHHCCCCCCCCCCCCCCCCC
DAAKAKTGISELSIEGNRLSKHNAHLYVDLSSIAKGFGVDKVASILDKYHASGYLVEIGG
HHHHHHCCHHHEEECCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
ELSIKGTKGDGSSWRVAIEKPTDDGMAVQQVIEPGTMAMATSGDYRNYYEEEGQRFTHII
EEEEEECCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCEEEEEE
DPRTGLPINHKLASVTVLHKKCMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEG
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCC
FKVYYSDAFKPFLK
EEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]