Click here to switch to the map view.

The map label for this gene is norR [H]

Identifier: 117919297

GI number: 117919297

Start: 978827

End: 980383

Strand: Reverse

Name: norR [H]

Synonym: Shewana3_0845

Alternate gene names: 117919297

Gene position: 980383-978827 (Counterclockwise)

Preceding gene: 117919298

Following gene: 117919296

Centisome position: 19.72

GC content: 52.67

Gene sequence:

>1557_bases
ATGGCCCTTAGTCAAACCGACCTTACCCGCATCGCACTGGACATCACCTCTGGTTTAGCCCACAGGGACCGCTTCTCACG
CTTGCTCGACACGGTAAGAGCTAACCTGCACTGTGATGCGGCGGCGTTACTCACCTTCCATGGACACTATTTTACCCCAC
TGGCCATCGACGGTTTGAACGAGGATGTGCTCGGCAGACGCTTTATCCTGAATGAGCATCCAAGGCTTGAAGCCATTGCC
CGTGCGGGGGATATAGTGCGCTTTCCCGCCGACAGTGAACTTGCCGATCCCTACGATGGCTTGATCCCCAATCAAACCGG
GGCATTGAAGGTTCATGCCTGTATCGGACTCCCCTTATTTGCCGACGAACAGCTTATCGGTGCCGTGACCATCGATGCCT
TTAATTCCCTGCAGTTCGATCAATTCAGTAATACCGAACTTCGCAGCTTAAGTGCGATTGCCGCCGCATCCTTAAGCAAC
GCCCTGCTGGTTGAAAAACTGGAGCGCATGGCACTCAATAGCCACTCAAGCCATGTGCAGGAAAAGAGCCCGAACCTTAA
CCACGATGCCGAAATCATCGGTAACTCGTCCCAGATGCAAAGCTTGAATCGGGAGATTGAAGTCGTTGCCCATAGCGACC
TTAACGTACTGATTTTAGGCGAGACAGGAACGGGCAAAGAATTAGTCGCCCAGTCAATCCATCAAAAATCCGCGAGATCT
CACAAACCCTTGGTCTATCTCAATTGCGCGGCGCTTCCTGAATCGGTTGCCGAAAGCGAACTCTTTGGCCATATCAAAGG
CGCGTTCACCGGCGCCATCAGCCATCGCAGTGGCAAGTTTGAAATGGCCGATAAGGGCACACTCTTTCTCGATGAGATTG
GCGAGCTTCCGCTCACGCTTCAGGCCAAGTTGCTGCGGGTCTTACAATATGGCGACATTCAGAAAGTGGGGGATGATCGC
AGCCTTAAAGTCGATGTGCGTATCATTGCTGCCACCAATAAGGATCTGAAAACGGAAGTGCTGGCTGGCCGTTTTAGGGC
CGATCTTTACCATAGGTTGAGCGTGTTTCCCCTGCTGGTGCCTCCACTGCGCGAGCGCGAGCAGGACATCACCTTGTTGA
GCGGATTCTTTGCCGAGCGATATCGGCAAAAGCTTGGGATGAAACAGCTTAATTTCAGTCCCAGTAGCTTAATCTTGCTC
AATCAATATACCTGGCCGGGCAATGTGCGCGAGCTCGAGCACGCCATTCACAGGGCGACCGTACTGGCGCGAGTCTCGGC
ACAGGATGGCTGCTGCACCATAGCGCCACAACATTTTGATTTACCGTTTAAACAAAGTCCTTTAGAAACAAACGCATCGA
CAAGTTTAAGCGTAAACGATATGCAGCTTCGCCCGTTGGAAGGAGCCAGTTTAGCCCAAGCGACCGACGCCTTTCAGCGT
GACTTCATTAAACAAGTGCTCACGGCACAAAACGGCAATTGGGCCGCCTCGGCCAGAGTCTTAGGACTCGACCCGGGCAA
TCTGCATCGCCTCGCAAAACGCTTAAGGCTAAAATAA

Upstream 100 bases:

>100_bases
TTATAGCCTTACCGCAATAACGGTTAGCAGTGTCTAAATAACCTGTGTCAATATAACAATCAATGCTATAAATCAGGGGA
ACCTCGCTGCAGGAGTTTTT

Downstream 100 bases:

>100_bases
GTGATAAATACGCCGTACGGATCATATTTCAGTTGAAATAATGGCCAAAATAAGGAAGGATGCGAGCTTCGCGCGCCAGT
GCACTTTGCCCAACAATTTG

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MALSQTDLTRIALDITSGLAHRDRFSRLLDTVRANLHCDAAALLTFHGHYFTPLAIDGLNEDVLGRRFILNEHPRLEAIA
RAGDIVRFPADSELADPYDGLIPNQTGALKVHACIGLPLFADEQLIGAVTIDAFNSLQFDQFSNTELRSLSAIAAASLSN
ALLVEKLERMALNSHSSHVQEKSPNLNHDAEIIGNSSQMQSLNREIEVVAHSDLNVLILGETGTGKELVAQSIHQKSARS
HKPLVYLNCAALPESVAESELFGHIKGAFTGAISHRSGKFEMADKGTLFLDEIGELPLTLQAKLLRVLQYGDIQKVGDDR
SLKVDVRIIAATNKDLKTEVLAGRFRADLYHRLSVFPLLVPPLREREQDITLLSGFFAERYRQKLGMKQLNFSPSSLILL
NQYTWPGNVRELEHAIHRATVLARVSAQDGCCTIAPQHFDLPFKQSPLETNASTSLSVNDMQLRPLEGASLAQATDAFQR
DFIKQVLTAQNGNWAASARVLGLDPGNLHRLAKRLRLK

Sequences:

>Translated_518_residues
MALSQTDLTRIALDITSGLAHRDRFSRLLDTVRANLHCDAAALLTFHGHYFTPLAIDGLNEDVLGRRFILNEHPRLEAIA
RAGDIVRFPADSELADPYDGLIPNQTGALKVHACIGLPLFADEQLIGAVTIDAFNSLQFDQFSNTELRSLSAIAAASLSN
ALLVEKLERMALNSHSSHVQEKSPNLNHDAEIIGNSSQMQSLNREIEVVAHSDLNVLILGETGTGKELVAQSIHQKSARS
HKPLVYLNCAALPESVAESELFGHIKGAFTGAISHRSGKFEMADKGTLFLDEIGELPLTLQAKLLRVLQYGDIQKVGDDR
SLKVDVRIIAATNKDLKTEVLAGRFRADLYHRLSVFPLLVPPLREREQDITLLSGFFAERYRQKLGMKQLNFSPSSLILL
NQYTWPGNVRELEHAIHRATVLARVSAQDGCCTIAPQHFDLPFKQSPLETNASTSLSVNDMQLRPLEGASLAQATDAFQR
DFIKQVLTAQNGNWAASARVLGLDPGNLHRLAKRLRLK
>Mature_517_residues
ALSQTDLTRIALDITSGLAHRDRFSRLLDTVRANLHCDAAALLTFHGHYFTPLAIDGLNEDVLGRRFILNEHPRLEAIAR
AGDIVRFPADSELADPYDGLIPNQTGALKVHACIGLPLFADEQLIGAVTIDAFNSLQFDQFSNTELRSLSAIAAASLSNA
LLVEKLERMALNSHSSHVQEKSPNLNHDAEIIGNSSQMQSLNREIEVVAHSDLNVLILGETGTGKELVAQSIHQKSARSH
KPLVYLNCAALPESVAESELFGHIKGAFTGAISHRSGKFEMADKGTLFLDEIGELPLTLQAKLLRVLQYGDIQKVGDDRS
LKVDVRIIAATNKDLKTEVLAGRFRADLYHRLSVFPLLVPPLREREQDITLLSGFFAERYRQKLGMKQLNFSPSSLILLN
QYTWPGNVRELEHAIHRATVLARVSAQDGCCTIAPQHFDLPFKQSPLETNASTSLSVNDMQLRPLEGASLAQATDAFQRD
FIKQVLTAQNGNWAASARVLGLDPGNLHRLAKRLRLK

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=519, Percent_Identity=60.3082851637765, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI1789087, Length=331, Percent_Identity=43.202416918429, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1790437, Length=331, Percent_Identity=43.8066465256798, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI87082117, Length=235, Percent_Identity=54.0425531914894, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1788550, Length=346, Percent_Identity=39.8843930635838, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790299, Length=360, Percent_Identity=40, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789233, Length=346, Percent_Identity=37.2832369942197, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1788905, Length=332, Percent_Identity=38.5542168674699, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=330, Percent_Identity=38.1818181818182, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786524, Length=273, Percent_Identity=41.7582417582418, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=297, Percent_Identity=39.3939393939394, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=36.4372469635627, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081858, Length=256, Percent_Identity=32.03125, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 57096; Mature: 56965

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSQTDLTRIALDITSGLAHRDRFSRLLDTVRANLHCDAAALLTFHGHYFTPLAIDGLN
CCCCCCCHHHEEHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEECCEEECCCC
EDVLGRRFILNEHPRLEAIARAGDIVRFPADSELADPYDGLIPNQTGALKVHACIGLPLF
HHHHCCCHHCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEE
ADEQLIGAVTIDAFNSLQFDQFSNTELRSLSAIAAASLSNALLVEKLERMALNSHSSHVQ
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EKSPNLNHDAEIIGNSSQMQSLNREIEVVAHSDLNVLILGETGTGKELVAQSIHQKSARS
HCCCCCCCCHHEECCCHHHHHHCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCC
HKPLVYLNCAALPESVAESELFGHIKGAFTGAISHRSGKFEMADKGTLFLDEIGELPLTL
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCEEHHHHCCCCCHH
QAKLLRVLQYGDIQKVGDDRSLKVDVRIIAATNKDLKTEVLAGRFRADLYHRLSVFPLLV
HHHHHHHHHCCCCHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPLREREQDITLLSGFFAERYRQKLGMKQLNFSPSSLILLNQYTWPGNVRELEHAIHRAT
CCHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
VLARVSAQDGCCTIAPQHFDLPFKQSPLETNASTSLSVNDMQLRPLEGASLAQATDAFQR
HHHEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHHHHHHHHHHH
DFIKQVLTAQNGNWAASARVLGLDPGNLHRLAKRLRLK
HHHHHHHHCCCCCEEECEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
ALSQTDLTRIALDITSGLAHRDRFSRLLDTVRANLHCDAAALLTFHGHYFTPLAIDGLN
CCCCCCHHHEEHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEECCEEECCCC
EDVLGRRFILNEHPRLEAIARAGDIVRFPADSELADPYDGLIPNQTGALKVHACIGLPLF
HHHHCCCHHCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEE
ADEQLIGAVTIDAFNSLQFDQFSNTELRSLSAIAAASLSNALLVEKLERMALNSHSSHVQ
CCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EKSPNLNHDAEIIGNSSQMQSLNREIEVVAHSDLNVLILGETGTGKELVAQSIHQKSARS
HCCCCCCCCHHEECCCHHHHHHCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCC
HKPLVYLNCAALPESVAESELFGHIKGAFTGAISHRSGKFEMADKGTLFLDEIGELPLTL
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCEEHHHHCCCCCHH
QAKLLRVLQYGDIQKVGDDRSLKVDVRIIAATNKDLKTEVLAGRFRADLYHRLSVFPLLV
HHHHHHHHHCCCCHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPLREREQDITLLSGFFAERYRQKLGMKQLNFSPSSLILLNQYTWPGNVRELEHAIHRAT
CCHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
VLARVSAQDGCCTIAPQHFDLPFKQSPLETNASTSLSVNDMQLRPLEGASLAQATDAFQR
HHHEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCHHHHHHHHHHH
DFIKQVLTAQNGNWAASARVLGLDPGNLHRLAKRLRLK
HHHHHHHHCCCCCEEECEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA