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The map label for this gene is kcsA [H]

Identifier: 117919276

GI number: 117919276

Start: 955599

End: 956423

Strand: Reverse

Name: kcsA [H]

Synonym: Shewana3_0824

Alternate gene names: 117919276

Gene position: 956423-955599 (Counterclockwise)

Preceding gene: 117919277

Following gene: 117919274

Centisome position: 19.24

GC content: 48.12

Gene sequence:

>825_bases
ATGACAGATAAAACCCCTTGGTCGCTCCGCTCTTTGGGTAATCCATCTCCCTTCGAATTCGCCATGATGCTGTTATCGCT
GCTCTCGGTCATCATAGTGTTAGTGATGACCTTTGGCCGACTCGACAAAGAAACCTACCGATTACTGTTTTTTATCGATA
CCACGATTTGCATGATTTTTATGGTCAACTTTTTCGTTGGCCTGTTTCGCGCACGCGATAAAGTTTTTTATCTGCGCCAT
CATTGGATCGATTTTATCGCCAGTATTCCCGCCATCGAGGCACTACGCATCGCGAGGGTGTTCCAAATTTTGCGGGTAAT
TCGTTTAATCCGCATGAGTCGCTCCTACCTTATTCCCTTGATAAAGCAGCGTAAACAAGCCACCCTCGCCAGTTTACTGG
TCGCTATGGTGACCATTTTAACCTTCGCATCTATCATCATTCTGATTGTCGAAAGTGGTACCGAAGGCGCCAATATCCAA
ACCGCCGAGCAAGCCATATGGTGGGCCTTAGTGACGATTTCGACCGTGGGTTATGGCGATTTTTATCCCGTCAGCACCGC
AGGGCATATTGTGGGCGGTATAGTGATAGTCAGTGGCGTAAGCTTTTTCGGGGTGATTTCGGGTTATATGGCCTCGGTAT
TTGTCGCCCCCGATGAAAGTGAGCGCCAAGAACGTCAGGACGCGCATAAGGCAGAGATTAAAAGCGAACTCGAAATGGCT
CTTGCCAGAATGGAAGAAAACCAGCGGCAGATGGAGCAGAATCAGGCGCAGATGTTGGCCAAAATTGCCGAGTTAAAACA
GGCATTGGAAGCCCAAAAGAATTAG

Upstream 100 bases:

>100_bases
ATAAACCTAAGTCGGGCGATTTATCACAAAGTTAATTTACTCATAGCGTAAACTCTTTTACCTTAGACATTCGCCTTAAA
ACACAGGGATCATGTTAGGC

Downstream 100 bases:

>100_bases
GAAGGCATGGCCTTCCTAAACTTTATTCAAAGTGGTGACGACCAATCGGCCGTTTACCAATAGGTCGTTTGCGTCATCGC
GTTTTGTCTCGATGCCTCCA

Product: Ion transport 2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTDKTPWSLRSLGNPSPFEFAMMLLSLLSVIIVLVMTFGRLDKETYRLLFFIDTTICMIFMVNFFVGLFRARDKVFYLRH
HWIDFIASIPAIEALRIARVFQILRVIRLIRMSRSYLIPLIKQRKQATLASLLVAMVTILTFASIIILIVESGTEGANIQ
TAEQAIWWALVTISTVGYGDFYPVSTAGHIVGGIVIVSGVSFFGVISGYMASVFVAPDESERQERQDAHKAEIKSELEMA
LARMEENQRQMEQNQAQMLAKIAELKQALEAQKN

Sequences:

>Translated_274_residues
MTDKTPWSLRSLGNPSPFEFAMMLLSLLSVIIVLVMTFGRLDKETYRLLFFIDTTICMIFMVNFFVGLFRARDKVFYLRH
HWIDFIASIPAIEALRIARVFQILRVIRLIRMSRSYLIPLIKQRKQATLASLLVAMVTILTFASIIILIVESGTEGANIQ
TAEQAIWWALVTISTVGYGDFYPVSTAGHIVGGIVIVSGVSFFGVISGYMASVFVAPDESERQERQDAHKAEIKSELEMA
LARMEENQRQMEQNQAQMLAKIAELKQALEAQKN
>Mature_273_residues
TDKTPWSLRSLGNPSPFEFAMMLLSLLSVIIVLVMTFGRLDKETYRLLFFIDTTICMIFMVNFFVGLFRARDKVFYLRHH
WIDFIASIPAIEALRIARVFQILRVIRLIRMSRSYLIPLIKQRKQATLASLLVAMVTILTFASIIILIVESGTEGANIQT
AEQAIWWALVTISTVGYGDFYPVSTAGHIVGGIVIVSGVSFFGVISGYMASVFVAPDESERQERQDAHKAEIKSELEMAL
ARMEENQRQMEQNQAQMLAKIAELKQALEAQKN

Specific function: Acts as a potassium ion channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI26051262, Length=231, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI26051260, Length=231, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI26051266, Length=231, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI26051264, Length=231, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI26051268, Length=231, Percent_Identity=25.974025974026, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436974, Length=176, Percent_Identity=27.8409090909091, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI119395748, Length=178, Percent_Identity=28.6516853932584, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI88758565, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI27436984, Length=246, Percent_Identity=24.7967479674797, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436981, Length=167, Percent_Identity=28.7425149700599, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436986, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI25952087, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4826784, Length=111, Percent_Identity=31.5315315315315, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4504817, Length=180, Percent_Identity=27.2222222222222, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4826782, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI9789987, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI25952092, Length=176, Percent_Identity=27.8409090909091, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI27436993, Length=125, Percent_Identity=27.2, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4504821, Length=112, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19071574, Length=110, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI236462242, Length=138, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17544122, Length=240, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25147242, Length=127, Percent_Identity=32.2834645669291, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25147238, Length=127, Percent_Identity=32.2834645669291, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71989369, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71989361, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71989381, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71989376, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25148255, Length=113, Percent_Identity=34.5132743362832, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193206869, Length=113, Percent_Identity=34.5132743362832, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994313, Length=193, Percent_Identity=27.979274611399, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564066, Length=240, Percent_Identity=22.5, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17737641, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161084970, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330117, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221330119, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281363095, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281363097, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45555859, Length=112, Percent_Identity=33.0357142857143, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45549143, Length=112, Percent_Identity=33.0357142857143, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24642910, Length=112, Percent_Identity=33.0357142857143, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24642916, Length=112, Percent_Identity=33.0357142857143, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24642914, Length=112, Percent_Identity=33.0357142857143, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007764, Length=111, Percent_Identity=30.6306306306306, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24656294, Length=111, Percent_Identity=30.6306306306306, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281365536, Length=111, Percent_Identity=30.6306306306306, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24656289, Length=111, Percent_Identity=30.6306306306306, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 31004; Mature: 30873

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKTPWSLRSLGNPSPFEFAMMLLSLLSVIIVLVMTFGRLDKETYRLLFFIDTTICMIF
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MVNFFVGLFRARDKVFYLRHHWIDFIASIPAIEALRIARVFQILRVIRLIRMSRSYLIPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQRKQATLASLLVAMVTILTFASIIILIVESGTEGANIQTAEQAIWWALVTISTVGYGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
FYPVSTAGHIVGGIVIVSGVSFFGVISGYMASVFVAPDESERQERQDAHKAEIKSELEMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
LARMEENQRQMEQNQAQMLAKIAELKQALEAQKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDKTPWSLRSLGNPSPFEFAMMLLSLLSVIIVLVMTFGRLDKETYRLLFFIDTTICMIF
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MVNFFVGLFRARDKVFYLRHHWIDFIASIPAIEALRIARVFQILRVIRLIRMSRSYLIPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQRKQATLASLLVAMVTILTFASIIILIVESGTEGANIQTAEQAIWWALVTISTVGYGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
FYPVSTAGHIVGGIVIVSGVSFFGVISGYMASVFVAPDESERQERQDAHKAEIKSELEMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
LARMEENQRQMEQNQAQMLAKIAELKQALEAQKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]