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The map label for this gene is argD [H]

Identifier: 117919063

GI number: 117919063

Start: 714876

End: 716093

Strand: Direct

Name: argD [H]

Synonym: Shewana3_0610

Alternate gene names: 117919063

Gene position: 714876-716093 (Clockwise)

Preceding gene: 117919062

Following gene: 117919064

Centisome position: 14.38

GC content: 49.43

Gene sequence:

>1218_bases
ATGAGCGTTGATATGAAGTTGAATCGTGCCCAGTTTGATGCGGTTATGGTGCCTAACTATGCGCCTGCTGCCGTAATCCC
TGTACGTGGCGAAGGAAGTCGAGTATGGGATCAAGAGGGTAACGAATTTATCGATTTTGCCGGCGGTATCGCGGTAAATT
GCTTAGGTCACTGTCATCCCGCCTTAGTAAATGCCTTAAAAACGCAAGGCGAAAAATTATGGCACCTGTCTAACGTGATG
ACCAACGAGCCAGCGCTTGAGCTTGCAACTAAGTTGGTTAACAGCACGTTTGCTGAGCGTGTGTATTTTGCTAACTCTGG
TGCCGAAGCCAACGAAGCGGCACTGAAATTAGCTCGTCGTTACGCCTTAGAAAAATTCGGCGTAGAGAAAGATGAAATCA
TCGCCTTCGATAAAGCCTTCCACGGTCGTACTTTCTTCACCGTGAGCGTTGGCGGTCAAGCGGCTTATTCAGATGGTTTT
GGTCCAAAACCACAAAGCATCACCCACTTACCTTATAACGATGTTGCGGCATTAGAAGCGGCCGTGTCGGATAAAACCTG
CGCCATTATGCTTGAGCCACTGCAGGGTGAGGGCGGTATTATCGATGCCGATCCTGCATTCTTAAAAGCGGTTCGCGAAC
TGGCCAACAAGCACAACGCACTAGTGATTTTCGACGAAGTACAAACTGGTGTTGGCCGTACTGGTGAACTCTACGCTTAC
ATGGGTACCGACATAGTGCCGGATATCCTGACCACGGCTAAAGCGCTGGGCGGCGGTTTCCCGATCGCAGCTATGCTGAC
GACCGCTGAAATTGCTGAGCACCTGAAAGTGGGTACTCACGGTTCAACCTACGGTGGTAACCCATTAGCTTGTGCTATCG
GTAACGCGGTATTAGACGTGGTTAACACACCAGAAGTCTTGAACGGTGTGAAACATCGCGAGCAGTTATTACGCGATGGT
CTGAACAAAATTAATGAAAAATATCATGTTTTCTCTGAAATTCGCGGTAAAGGCTTGCTGTTAGGGGCGGTTCTAAACGA
ACAGTACCAAGGTCGTTCACGTGACTTTTTAGTAGCGTCTGTTGCAGAAGGCTTAATGAGCCTGATGGCGGGTGCTAACG
TGGTACGTTTTGCTCCTTCACTGGTGATCCCTGAGGCAGATATTGCAGAAGGCCTAGCACGTTTTGAGCGTGCTGTGGCG
AGCATCGCTGCTGCCTAA

Upstream 100 bases:

>100_bases
TAGACACAAGCATACCCTGTATCACTAACTCAAGATAAAGATACGTTGGGGACTCAGACGGCTCCCGAGGCCGTTACATT
TAAACAAAGGATGAAGAAGA

Downstream 100 bases:

>100_bases
GCGACCAAAGGAGTGCTGAATCTTATTCGCACTCCTTTTTTGTCAGGGAATACTTGCGTGCATCCATCCTGTCTTTTTCA
AGATAGGCGCCTTGTTGCAC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSVDMKLNRAQFDAVMVPNYAPAAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHPALVNALKTQGEKLWHLSNVM
TNEPALELATKLVNSTFAERVYFANSGAEANEAALKLARRYALEKFGVEKDEIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHLPYNDVAALEAAVSDKTCAIMLEPLQGEGGIIDADPAFLKAVRELANKHNALVIFDEVQTGVGRTGELYAY
MGTDIVPDILTTAKALGGGFPIAAMLTTAEIAEHLKVGTHGSTYGGNPLACAIGNAVLDVVNTPEVLNGVKHREQLLRDG
LNKINEKYHVFSEIRGKGLLLGAVLNEQYQGRSRDFLVASVAEGLMSLMAGANVVRFAPSLVIPEADIAEGLARFERAVA
SIAAA

Sequences:

>Translated_405_residues
MSVDMKLNRAQFDAVMVPNYAPAAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHPALVNALKTQGEKLWHLSNVM
TNEPALELATKLVNSTFAERVYFANSGAEANEAALKLARRYALEKFGVEKDEIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHLPYNDVAALEAAVSDKTCAIMLEPLQGEGGIIDADPAFLKAVRELANKHNALVIFDEVQTGVGRTGELYAY
MGTDIVPDILTTAKALGGGFPIAAMLTTAEIAEHLKVGTHGSTYGGNPLACAIGNAVLDVVNTPEVLNGVKHREQLLRDG
LNKINEKYHVFSEIRGKGLLLGAVLNEQYQGRSRDFLVASVAEGLMSLMAGANVVRFAPSLVIPEADIAEGLARFERAVA
SIAAA
>Mature_404_residues
SVDMKLNRAQFDAVMVPNYAPAAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHPALVNALKTQGEKLWHLSNVMT
NEPALELATKLVNSTFAERVYFANSGAEANEAALKLARRYALEKFGVEKDEIIAFDKAFHGRTFFTVSVGGQAAYSDGFG
PKPQSITHLPYNDVAALEAAVSDKTCAIMLEPLQGEGGIIDADPAFLKAVRELANKHNALVIFDEVQTGVGRTGELYAYM
GTDIVPDILTTAKALGGGFPIAAMLTTAEIAEHLKVGTHGSTYGGNPLACAIGNAVLDVVNTPEVLNGVKHREQLLRDGL
NKINEKYHVFSEIRGKGLLLGAVLNEQYQGRSRDFLVASVAEGLMSLMAGANVVRFAPSLVIPEADIAEGLARFERAVAS
IAAA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=37.3401534526854, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=37.2093023255814, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI13994255, Length=415, Percent_Identity=30.3614457831325, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=28.0660377358491, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=28.7917737789203, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI24119277, Length=395, Percent_Identity=27.8481012658228, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=26.8867924528302, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=24.6376811594203, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=24.6376811594203, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=24.6376811594203, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=62.65664160401, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=58.4382871536524, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=35.8395989974937, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI145693181, Length=369, Percent_Identity=35.230352303523, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=33.7531486146096, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786991, Length=327, Percent_Identity=34.8623853211009, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786349, Length=313, Percent_Identity=29.073482428115, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=35.3723404255319, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=29.2161520190024, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=278, Percent_Identity=33.8129496402878, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=27.972027972028, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=419, Percent_Identity=25.5369928400955, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=162, Percent_Identity=33.9506172839506, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=410, Percent_Identity=37.8048780487805, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.4913151364764, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=340, Percent_Identity=28.5294117647059, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=25.2336448598131, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=36.0824742268041, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI28574759, Length=438, Percent_Identity=30.365296803653, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=29.8440979955457, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=28.0952380952381, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=22.9166666666667, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=22.9166666666667, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=22.9166666666667, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43225; Mature: 43094

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDMKLNRAQFDAVMVPNYAPAAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHP
CCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCEEEHHCCCHHHHHHHHHHH
ALVNALKTQGEKLWHLSNVMTNEPALELATKLVNSTFAERVYFANSGAEANEAALKLARR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YALEKFGVEKDEIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHLPYNDVAALEA
HHHHHHCCCHHHEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCCHHHHHHH
AVSDKTCAIMLEPLQGEGGIIDADPAFLKAVRELANKHNALVIFDEVQTGVGRTGELYAY
HHCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEE
MGTDIVPDILTTAKALGGGFPIAAMLTTAEIAEHLKVGTHGSTYGGNPLACAIGNAVLDV
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLNGVKHREQLLRDGLNKINEKYHVFSEIRGKGLLLGAVLNEQYQGRSRDFLVAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHH
VAEGLMSLMAGANVVRFAPSLVIPEADIAEGLARFERAVASIAAA
HHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVDMKLNRAQFDAVMVPNYAPAAVIPVRGEGSRVWDQEGNEFIDFAGGIAVNCLGHCHP
CCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCEEEHHCCCHHHHHHHHHHH
ALVNALKTQGEKLWHLSNVMTNEPALELATKLVNSTFAERVYFANSGAEANEAALKLARR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YALEKFGVEKDEIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHLPYNDVAALEA
HHHHHHCCCHHHEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCCHHHHHHH
AVSDKTCAIMLEPLQGEGGIIDADPAFLKAVRELANKHNALVIFDEVQTGVGRTGELYAY
HHCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEE
MGTDIVPDILTTAKALGGGFPIAAMLTTAEIAEHLKVGTHGSTYGGNPLACAIGNAVLDV
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLNGVKHREQLLRDGLNKINEKYHVFSEIRGKGLLLGAVLNEQYQGRSRDFLVAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHH
VAEGLMSLMAGANVVRFAPSLVIPEADIAEGLARFERAVASIAAA
HHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]