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The map label for this gene is ttdR [H]

Identifier: 117918864

GI number: 117918864

Start: 466181

End: 467113

Strand: Direct

Name: ttdR [H]

Synonym: Shewana3_0407

Alternate gene names: 117918864

Gene position: 466181-467113 (Clockwise)

Preceding gene: 117918861

Following gene: 117918867

Centisome position: 9.38

GC content: 50.48

Gene sequence:

>933_bases
ATGCTGCTGAATGATCTCGCACTATTTGTTCGCGTTGCCGACTGCGGCAGTATTTCGGCTGCCGCGGTCGAAATGGAACT
CTCGGCAGCATCTGCAAGCGCAGCGATTAAACGGCTTGAAAAACAACTTGATACCAGCCTTTTTGTACGTACGACCCGAA
GCCTTAGATTAACCGCACAGGGAGAGCGTTACCTTATCCATTGCCGCCGTGCCTTAAGTGATCTTGCACTCGGGGAGCAG
GCGATCGCCAGCGATAAAGGTAAAGTCTCTGGTACCTTGAGCCTCTCAGTTTCATCCGATTTTGGGCGTAACTTATTCGT
CCCTTGGCTCGATGATTTCCTGTTAGATTTTCCGCAGCTACAGGTGCGACTGCATTTGGGTGATAACATCAGCAGCTTTT
ACCACGACAAAATTGATGTCGCGGTGCGTTACGGTAAACCGCAGGACTCCAATCAGGTCGCATTTCCGATTTGCTGCGCC
GACCGATTACTATGCGCTTCACCTGAATATCTCGCCAAGTTTGGTAAACCCGAAACCTTAGAACAGTTAGCTCAGCACAA
TTGTTTGTTTTATAAACTCGATGACCGCACCCATGATCAATGGCAATTTGAGCGTGATGGCCAGGAATTTAAAATCCGCG
TGACGGGTAATCGCAGCGCCAATGATGCTGAAATTGCGCGCCGCTGGGCCGTGGCTGGTAAGGGTTTAGTGTTCAAGTCG
AGCTTAGATCTGGCGGAGGATATTATGGCTGGGCGCCTTGTGCCCTTGCTGCCCGAATATCGGGGCGAATCGGTCAATTT
ATACTTAGTGTGCCCTGGGCGTGAGCATGTCACGCCCGTGGTGCTGTTACTTCGTGAAATGCTCAGGCAACAGACTCAAG
CCTTAAGCCGTGCCCTAGCGACATACCTTAAGTCTGAAACGCAGTTTAAATAA

Upstream 100 bases:

>100_bases
GCTGGTGCCTGTACTTGTCAATGGCAACTATTGTGTGGAATATTAAAGCCTAGATAAACGGGGTAAACTTTGTAATTTTT
TCAAAGGATTTTTGAAAATC

Downstream 100 bases:

>100_bases
CAATTGAATGCGGGAATCTAAGGGAGTTCGCTGAGGTTTGATAAGTGGATTACCTTCGTGATTTCCTCTCTGAAGAGGGC
TCAACGCTCTGTGATTTAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLLNDLALFVRVADCGSISAAAVEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKVSGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICCA
DRLLCASPEYLAKFGKPETLEQLAQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGESVNLYLVCPGREHVTPVVLLLREMLRQQTQALSRALATYLKSETQFK

Sequences:

>Translated_310_residues
MLLNDLALFVRVADCGSISAAAVEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKVSGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICCA
DRLLCASPEYLAKFGKPETLEQLAQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGESVNLYLVCPGREHVTPVVLLLREMLRQQTQALSRALATYLKSETQFK
>Mature_310_residues
MLLNDLALFVRVADCGSISAAAVEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQGERYLIHCRRALSDLALGEQ
AIASDKGKVSGTLSLSVSSDFGRNLFVPWLDDFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICCA
DRLLCASPEYLAKFGKPETLEQLAQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLAEDIMAGRLVPLLPEYRGESVNLYLVCPGREHVTPVVLLLREMLRQQTQALSRALATYLKSETQFK

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=270, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=33.2179930795848, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786401, Length=254, Percent_Identity=31.8897637795276, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=30.4498269896194, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789639, Length=268, Percent_Identity=29.4776119402985, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=26.8817204301075, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786448, Length=277, Percent_Identity=28.8808664259928, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=24.2753623188406, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789173, Length=270, Percent_Identity=28.1481481481481, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI157672245, Length=237, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=21.7687074829932, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=129, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34727; Mature: 34727

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNDLALFVRVADCGSISAAAVEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQ
CCHHHEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHHEEEECCEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKVSGTLSLSVSSDFGRNLFVPWLDDFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICCADRLLCASPEYLAKFGKPETL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEEEHHCHHHCCCCHHHHHCCCCHHH
EQLAQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLAEDIMAGRLVPLLPEYRGESVNLYLVCPGREHVTPVVLLLREMLRQQTQALSRALA
CHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TYLKSETQFK
HHHHHCCCCC
>Mature Secondary Structure
MLLNDLALFVRVADCGSISAAAVEMELSAASASAAIKRLEKQLDTSLFVRTTRSLRLTAQ
CCHHHEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHHEEEECCEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKVSGTLSLSVSSDFGRNLFVPWLDDFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICCADRLLCASPEYLAKFGKPETL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEEEHHCHHHCCCCHHHHHCCCCHHH
EQLAQHNCLFYKLDDRTHDQWQFERDGQEFKIRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLAEDIMAGRLVPLLPEYRGESVNLYLVCPGREHVTPVVLLLREMLRQQTQALSRALA
CHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TYLKSETQFK
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]